lepromatous leprosy Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A leprosy that results in early cutaneous lesions which consist of pale macules that are small, diffuse, and symmetric. This form of leprosy is characterized by hypoesthesia over extensor surfaces of the distal extremities, alopecia affecting lateral aspects of the eyebrows, saddle-nose deformity and oral lepromas. (Human Disease Ontology, DOID_10887)
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Genes

87 genes co-occuring with the disease lepromatous leprosy in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 2.32929
IL2 interleukin 2 1.41358
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.2369
IL12RB2 interleukin 12 receptor, beta 2 1.22518
LSR lipolysis stimulated lipoprotein receptor 0.986428
CD79A CD79a molecule, immunoglobulin-associated alpha 0.945354
TLR2 toll-like receptor 2 0.935385
ARHGAP44 Rho GTPase activating protein 44 0.904854
NELFCD negative elongation factor complex member C/D 0.893359
CD4 CD4 molecule 0.88434
LYZ lysozyme 0.824128
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.806488
CORO1A coronin, actin binding protein, 1A 0.787623
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.772887
SLAMF1 signaling lymphocytic activation molecule family member 1 0.746798
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 0.74436
ALB albumin 0.707559
TNF tumor necrosis factor 0.70233
PEX3 peroxisomal biogenesis factor 3 0.674713
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.573439
IL10 interleukin 10 0.532314
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 0.532314
IL2RA interleukin 2 receptor, alpha 0.522273
IFNGR1 interferon gamma receptor 1 0.498849
CD80 CD80 molecule 0.490072
DEFB103B defensin, beta 103B 0.488169
TOLLIP toll interacting protein 0.488169
IL1B interleukin 1, beta 0.469576
PEX2 peroxisomal biogenesis factor 2 0.463149
MBL2 mannose-binding lectin (protein C) 2, soluble 0.453716
C1QTNF5 C1q and tumor necrosis factor related protein 5 0.451831
PLIN2 perilipin 2 0.450701
ALPPL2 alkaline phosphatase, placental-like 2 0.412779
FCN3 ficolin (collagen/fibrinogen domain containing) 3 0.412779
ALPP alkaline phosphatase, placental 0.412405
ALPL alkaline phosphatase, liver/bone/kidney 0.411657
ACPP acid phosphatase, prostate 0.408292
ICAM1 intercellular adhesion molecule 1 0.407172
HLA-A major histocompatibility complex, class I, A 0.406425
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.403811
CD1B CD1b molecule 0.397098
SAA1 serum amyloid A1 0.38111
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 0.360395
CXCL10 chemokine (C-X-C motif) ligand 10 0.33651
CRP C-reactive protein, pentraxin-related 0.336144
BCHE butyrylcholinesterase 0.332852
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.324823
HSPE1 heat shock 10kDa protein 1 0.316092
GNG8 guanine nucleotide binding protein (G protein), gamma 8 0.312102
RNF112 ring finger protein 112 0.309204
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.305587
LDHA lactate dehydrogenase A 0.304142
LEP leptin 0.301254
MASP2 mannan-binding lectin serine peptidase 2 0.292616
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.290462
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 0.279367
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.279011
CD3D CD3d molecule, delta (CD3-TCR complex) 0.275801
RORC RAR-related orphan receptor C 0.272597
IL12RB1 interleukin 12 receptor, beta 1 0.27153
TGFB1 transforming growth factor, beta 1 0.266913
S100A10 S100 calcium binding protein A10 0.254183
IL31 interleukin 31 0.24715
LTF lactotransferrin 0.242945
IL12B interleukin 12B 0.241196
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.239799
CD68 CD68 molecule 0.236312
DEFB1 defensin, beta 1 0.235268
FOXP3 forkhead box P3 0.216332
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 0.215314
LTA lymphotoxin alpha 0.213283
SHMT1 serine hydroxymethyltransferase 1 (soluble) 0.208245
CD8B CD8b molecule 0.201308
GLB1 galactosidase, beta 1 0.196459
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 0.196139
GUSB glucuronidase, beta 0.182086
LDHC lactate dehydrogenase C 0.180652
PLIN1 perilipin 1 0.180084
KRT16 keratin 16, type I 0.177576
TLR6 toll-like receptor 6 0.174354
HLA-C major histocompatibility complex, class I, C 0.171286
PRRC2A proline-rich coiled-coil 2A 0.170789
LDHB lactate dehydrogenase B 0.169812
CD2 CD2 molecule 0.165655
S100A12 S100 calcium binding protein A12 0.165001
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.162306
TF transferrin 0.160203