leprosy Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid. (Experimental Factor Ontology, EFO_0001054)
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Genes

66 genes associated with the disease leprosy in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ADGB androglobin
ALS2CL ALS2 C-terminal like
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
C6ORF15 chromosome 6 open reading frame 15
C7ORF69 chromosome 7 open reading frame 69
CCDC122 coiled-coil domain containing 122
CD209 CD209 molecule
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like)
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
GNG2 guanine nucleotide binding protein (G protein), gamma 2
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IFNG interferon, gamma
IL10 interleukin 10
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
IL2 interleukin 2
IL6 interleukin 6
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR2DP1 killer cell immunoglobulin-like receptor, two domains, pseudogene 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS3 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DL3 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 3
KIR3DP1 killer cell immunoglobulin-like receptor, three domains, pseudogene 1
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
LACC1 laccase (multicopper oxidoreductase) domain containing 1
LAMA2 laminin, alpha 2
LTA lymphotoxin alpha
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MEN1 multiple endocrine neoplasia I
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
PACRG PARK2 co-regulated
PARK2 parkin RBR E3 ubiquitin protein ligase
PKD1L1 polycystic kidney disease 1 like 1
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RIPK2 receptor-interacting serine-threonine kinase 2
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TGFB1 transforming growth factor, beta 1
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
VARS2 valyl-tRNA synthetase 2, mitochondrial
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor