leprosy Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid. (Experimental Factor Ontology, EFO_0001054)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:1024
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Genes

25 genes associated with the disease leprosy in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
LACC1 laccase (multicopper oxidoreductase) domain containing 1 2.60034
CCDC122 coiled-coil domain containing 122 2.29514
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 2.05009
RIPK2 receptor-interacting serine-threonine kinase 2 1.8787
FILIP1 filamin A interacting protein 1 1.85353
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 1.69888
HLA-C major histocompatibility complex, class I, C 1.30111
HLA-DRA major histocompatibility complex, class II, DR alpha 1.29498
HLA-DOB major histocompatibility complex, class II, DO beta 1.28247
MATN4 matrilin 4 1.14671
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 1.12663
ALS2CL ALS2 C-terminal like 1.12405
SEPHS1 selenophosphate synthetase 1 1.09895
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 1.05914
DHDDS dehydrodolichyl diphosphate synthase 1.04977
SH3GL2 SH3-domain GRB2-like 2 1.04514
C6ORF15 chromosome 6 open reading frame 15 1.02661
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 1.00407
UPP2 uridine phosphorylase 2 1.00203
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like) 0.991255
VARS2 valyl-tRNA synthetase 2, mitochondrial 0.974321
IL23R interleukin 23 receptor 0.973885
GNG2 guanine nucleotide binding protein (G protein), gamma 2 0.951514
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 0.890183
NOD2 nucleotide-binding oligomerization domain containing 2 0.749856