leprosy Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid. (Experimental Factor Ontology, EFO_0001054)
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Genes

75 genes co-occuring with the biological term leprosy in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
APOH apolipoprotein H (beta-2-glycoprotein I)
BCL10 B-cell CLL/lymphoma 10
BTNL2 butyrophilin-like 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCDC122 coiled-coil domain containing 122
CCL11 chemokine (C-C motif) ligand 11
CD1B CD1b molecule
CD209 CD209 molecule
CFH complement factor H
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CUBN cubilin (intrinsic factor-cobalamin receptor)
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
DEFB1 defensin, beta 1
DEFB103B defensin, beta 103B
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FOXP3 forkhead box P3
GSTM1 glutathione S-transferase mu 1
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
IDO1 indoleamine 2,3-dioxygenase 1
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IL10 interleukin 10
IL12B interleukin 12B
IL12RB1 interleukin 12 receptor, beta 1
IL12RB2 interleukin 12 receptor, beta 2
IL17A interleukin 17A
IL17F interleukin 17F
IL18R1 interleukin 18 receptor 1
IL23R interleukin 23 receptor
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
IRGM immunity-related GTPase family, M
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KRT10 keratin 10, type I
LACC1 laccase (multicopper oxidoreductase) domain containing 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LGALS3 lectin, galactoside-binding, soluble, 3
LRRK2 leucine-rich repeat kinase 2
LTA lymphotoxin alpha
LTA4H leukotriene A4 hydrolase
MASP2 mannan-binding lectin serine peptidase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MICA MHC class I polypeptide-related sequence A
MIR181A1 microRNA 181a-1
MIR21 microRNA 21
MRC1 mannose receptor, C type 1
NEBL nebulette
NINJ1 ninjurin 1
NLRP1 NLR family, pyrin domain containing 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
PACRG PARK2 co-regulated
PARK2 parkin RBR E3 ubiquitin protein ligase
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB32 RAB32, member RAS oncogene family
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TGFB1 transforming growth factor, beta 1
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TOLLIP toll interacting protein
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa