lethality Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

79 genes co-occuring with the biological term lethality in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ANTXR2 anthrax toxin receptor 2
APOE apolipoprotein E
ARFRP1 ADP-ribosylation factor related protein 1
ARL1 ADP-ribosylation factor-like 1
ATR ATR serine/threonine kinase
ATXN1 ataxin 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BDNF brain-derived neurotrophic factor
BLM Bloom syndrome, RecQ helicase-like
BMP4 bone morphogenetic protein 4
BRCA2 breast cancer 2, early onset
CBS cystathionine-beta-synthase
CCNE1 cyclin E1
CDK1 cyclin-dependent kinase 1
CDK5 cyclin-dependent kinase 5
CHEK1 checkpoint kinase 1
CRP C-reactive protein, pentraxin-related
CSPP1 centrosome and spindle pole associated protein 1
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTSB cathepsin B
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EGFR epidermal growth factor receptor
EMILIN1 elastin microfibril interfacer 1
EMILIN2 elastin microfibril interfacer 2
ERCC6 excision repair cross-complementation group 6
FAM20C family with sequence similarity 20, member C
FOXN3 forkhead box N3
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GATA2 GATA binding protein 2
HCCS holocytochrome c synthase
HHEX hematopoietically expressed homeobox
HOXA13 homeobox A13
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1B heat shock 70kDa protein 1B
HTRA2 HtrA serine peptidase 2
IL18 interleukin 18
IL1RN interleukin 1 receptor antagonist
IL24 interleukin 24
IL32 interleukin 32
IL7 interleukin 7
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding)
KRT1 keratin 1, type II
KRT18 keratin 18, type I
LRP6 low density lipoprotein receptor-related protein 6
MGMT O-6-methylguanine-DNA methyltransferase
MOB1A MOB kinase activator 1A
MOSPD3 motile sperm domain containing 3
MT-ND3 NADH dehydrogenase, subunit 3 (complex I)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
NAPRT nicotinate phosphoribosyltransferase
NFE2L2 nuclear factor, erythroid 2-like 2
NFIA nuclear factor I/A
NSDHL NAD(P) dependent steroid dehydrogenase-like
PARP1 poly (ADP-ribose) polymerase 1
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PLAU plasminogen activator, urokinase
RAD51 RAD51 recombinase
RAD9A RAD9 homolog A (S. pombe)
RTEL1 regulator of telomere elongation helicase 1
SAE1 SUMO1 activating enzyme subunit 1
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPINT2 serine peptidase inhibitor, Kunitz type, 2
TARDBP TAR DNA binding protein
TNF tumor necrosis factor
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TP73 tumor protein p73
UBA2 ubiquitin-like modifier activating enzyme 2
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6