| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the letrozole-2916 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADORA3 | adenosine A3 receptor |
| AEN | apoptosis enhancing nuclease |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| AQP9 | aquaporin 9 |
| AREG | amphiregulin |
| BIN1 | bridging integrator 1 |
| BMP7 | bone morphogenetic protein 7 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CCL8 | chemokine (C-C motif) ligand 8 |
| CD59 | CD59 molecule, complement regulatory protein |
| CD84 | CD84 molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DPYSL3 | dihydropyrimidinase-like 3 |
| ELN | elastin |
| EML2 | echinoderm microtubule associated protein like 2 |
| EMP2 | epithelial membrane protein 2 |
| FAM76A | family with sequence similarity 76, member A |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| FBXO31 | F-box protein 31 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase |
| FKBP5 | FK506 binding protein 5 |
| FLT3 | fms-related tyrosine kinase 3 |
| FPR1 | formyl peptide receptor 1 |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GAS2 | growth arrest-specific 2 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GPR107 | G protein-coupled receptor 107 |
| GSN | gelsolin |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 |
| HOXA11 | homeobox A11 |
| IGL | immunoglobulin lambda locus |
| IKZF4 | IKAROS family zinc finger 4 (Eos) |
| IL1R2 | interleukin 1 receptor, type II |
| IL1RN | interleukin 1 receptor antagonist |
| INHBC | inhibin, beta C |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 |
| ITIH4 | inter-alpha-trypsin inhibitor heavy chain family, member 4 |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| KRT86 | keratin 86, type II |
| LATS1 | large tumor suppressor kinase 1 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MTMR8 | myotubularin related protein 8 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NLRP1 | NLR family, pyrin domain containing 1 |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PAX5 | paired box 5 |
| PER1 | period circadian clock 1 |
| PGAP3 | post-GPI attachment to proteins 3 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTTG2 | pituitary tumor-transforming 2 |
| PVR | poliovirus receptor |
| RAB26 | RAB26, member RAS oncogene family |
| RGS12 | regulator of G-protein signaling 12 |
| RHOH | ras homolog family member H |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RMND5B | required for meiotic nuclear division 5 homolog B (S. cerevisiae) |
| SDC2 | syndecan 2 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SLAMF1 | signaling lymphocytic activation molecule family member 1 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SMAD3 | SMAD family member 3 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TGFB1 | transforming growth factor, beta 1 |
| THAP3 | THAP domain containing, apoptosis associated protein 3 |
| THBS1 | thrombospondin 1 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM51 | transmembrane protein 51 |
| TMOD1 | tropomodulin 1 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TSC22D3 | TSC22 domain family, member 3 |
| ZBTB16 | zinc finger and BTB domain containing 16 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| AOAH | acyloxyacyl hydrolase (neutrophil) |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| B3GNT1 | |
| BAG3 | BCL2-associated athanogene 3 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BBS1 | Bardet-Biedl syndrome 1 |
| CCDC69 | coiled-coil domain containing 69 |
| CCDC88C | coiled-coil domain containing 88C |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD37 | CD37 molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHMP6 | charged multivesicular body protein 6 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CSAD | cysteine sulfinic acid decarboxylase |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DEFB1 | defensin, beta 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FANCF | Fanconi anemia, complementation group F |
| FPGS | folylpolyglutamate synthase |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GID4 | GID complex subunit 4 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GPR85 | G protein-coupled receptor 85 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL1B | interleukin 1, beta |
| ITPKC | inositol-trisphosphate 3-kinase C |
| JUNB | jun B proto-oncogene |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KIF21B | kinesin family member 21B |
| KIF24 | kinesin family member 24 |
| KIF3B | kinesin family member 3B |
| KPTN | kaptin (actin binding protein) |
| LNPEP | leucyl/cystinyl aminopeptidase |
| MAP1S | microtubule-associated protein 1S |
| MAP3K11 | mitogen-activated protein kinase kinase kinase 11 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MED22 | mediator complex subunit 22 |
| METTL8 | methyltransferase like 8 |
| MIR22HG | MIR22 host gene |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| MX1 | MX dynamin-like GTPase 1 |
| MXD3 | MAX dimerization protein 3 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NLK | nemo-like kinase |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PRR4 | proline rich 4 (lacrimal) |
| PSKH1 | protein serine kinase H1 |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RFPL1S | RFPL1 antisense RNA 1 |
| RIN1 | Ras and Rab interactor 1 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| SNHG20 | small nucleolar RNA host gene 20 |
| SYCP2 | synaptonemal complex protein 2 |
| TESK1 | testis-specific kinase 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THBS3 | thrombospondin 3 |
| THOP1 | thimet oligopeptidase 1 |
| TLN1 | talin 1 |
| TMEM104 | transmembrane protein 104 |
| TMEM115 | transmembrane protein 115 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TRABD | TraB domain containing |
| TRIM36 | tripartite motif containing 36 |
| TROAP | trophinin associated protein |
| USB1 | U6 snRNA biogenesis 1 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| VCPKMT | valosin containing protein lysine (K) methyltransferase |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF408 | zinc finger protein 408 |
| ZNF623 | zinc finger protein 623 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A |
