| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the letrozole-4240 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ACTN2 | actinin, alpha 2 |
| ADCY2 | adenylate cyclase 2 (brain) |
| ADCY9 | adenylate cyclase 9 |
| AGBL3 | ATP/GTP binding protein-like 3 |
| AKAP11 | A kinase (PRKA) anchor protein 11 |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ASTN2 | astrotactin 2 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| ATXN2L | ataxin 2-like |
| ATXN7L1 | ataxin 7-like 1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BTBD18 | BTB (POZ) domain containing 18 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C18ORF25 | chromosome 18 open reading frame 25 |
| CDC14A | cell division cycle 14A |
| CFH | complement factor H |
| COL4A4 | collagen, type IV, alpha 4 |
| COL5A1 | collagen, type V, alpha 1 |
| COMMD4 | COMM domain containing 4 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EPS8L1 | EPS8-like 1 |
| FAIM2 | Fas apoptotic inhibitory molecule 2 |
| FAM49B | family with sequence similarity 49, member B |
| FBXO11 | F-box protein 11 |
| FCAR | Fc fragment of IgA receptor |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GIMAP5 | GTPase, IMAP family member 5 |
| GPATCH4 | G patch domain containing 4 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HBS1L | HBS1-like translational GTPase |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL1RN | interleukin 1 receptor antagonist |
| INHBC | inhibin, beta C |
| INO80D | INO80 complex subunit D |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLF4 | Kruppel-like factor 4 (gut) |
| KRT7 | keratin 7, type II |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MIER2 | mesoderm induction early response 1, family member 2 |
| NAV3 | neuron navigator 3 |
| NCALD | neurocalcin delta |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NNMT | nicotinamide N-methyltransferase |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NR1H4 | nuclear receptor subfamily 1, group H, member 4 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PCDH17 | protocadherin 17 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIGO | phosphatidylinositol glycan anchor biosynthesis, class O |
| PITX2 | paired-like homeodomain 2 |
| PKP4 | plakophilin 4 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLA2R1 | phospholipase A2 receptor 1, 180kDa |
| PLXNA2 | plexin A2 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RNF32 | ring finger protein 32 |
| RPS3A | ribosomal protein S3A |
| RUNX1 | runt-related transcription factor 1 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCN2A | sodium channel, voltage gated, type II alpha subunit |
| SEMG2 | semenogelin II |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SP100 | SP100 nuclear antigen |
| SRCAP | Snf2-related CREBBP activator protein |
| SUGP1 | SURP and G patch domain containing 1 |
| SYN2 | synapsin II |
| SYT17 | synaptotagmin XVII |
| TBC1D30 | TBC1 domain family, member 30 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TGM4 | transglutaminase 4 |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TLX3 | T-cell leukemia homeobox 3 |
| TMEM206 | transmembrane protein 206 |
| TNIK | TRAF2 and NCK interacting kinase |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| VPRBP | Vpr (HIV-1) binding protein |
| VPREB1 | pre-B lymphocyte 1 |
| VPS9D1 | VPS9 domain containing 1 |
| YIPF4 | Yip1 domain family, member 4 |
| ZFAND5 | zinc finger, AN1-type domain 5 |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF141 | zinc finger protein 141 |
| ZNF268 | zinc finger protein 268 |
| ZNF518A | zinc finger protein 518A |
| ZNF613 | zinc finger protein 613 |
| ZNF614 | zinc finger protein 614 |
| Symbol | Name |
|---|---|
| ACE | angiotensin I converting enzyme |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AK5 | adenylate kinase 5 |
| ALOX12 | arachidonate 12-lipoxygenase |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| AXIN1 | axin 1 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CASS4 | Cas scaffolding protein family member 4 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CDHR2 | cadherin-related family member 2 |
| CELP | carboxyl ester lipase pseudogene |
| CNN1 | calponin 1, basic, smooth muscle |
| COMP | cartilage oligomeric matrix protein |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DEAF1 | DEAF1 transcription factor |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DSPP | dentin sialophosphoprotein |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM120C | family with sequence similarity 120C |
| FGF20 | fibroblast growth factor 20 |
| FLT4 | fms-related tyrosine kinase 4 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GRM4 | glutamate receptor, metabotropic 4 |
| HAMP | hepcidin antimicrobial peptide |
| HESX1 | HESX homeobox 1 |
| HIST1H1D | histone cluster 1, H1d |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOXB2 | homeobox B2 |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| IL2 | interleukin 2 |
| IMPG1 | interphotoreceptor matrix proteoglycan 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA1549L | KIAA1549-like |
| KIF13B | kinesin family member 13B |
| KIRREL | kin of IRRE like (Drosophila) |
| KLC2 | kinesin light chain 2 |
| KLF13 | Kruppel-like factor 13 |
| KLHL36 | kelch-like family member 36 |
| KRT31 | keratin 31, type I |
| LATS1 | large tumor suppressor kinase 1 |
| LENEP | lens epithelial protein |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MGP | matrix Gla protein |
| MMP13 | matrix metallopeptidase 13 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MTSS1L | metastasis suppressor 1-like |
| MUC3A | mucin 3A, cell surface associated |
| MYO15A | myosin XVA |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NOTCH4 | notch 4 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OR10H1 | olfactory receptor, family 10, subfamily H, member 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PALM | paralemmin |
| PCDH12 | protocadherin 12 |
| PDE12 | phosphodiesterase 12 |
| PIP | prolactin-induced protein |
| PLBD1 | phospholipase B domain containing 1 |
| PLXNB3 | plexin B3 |
| PRM2 | protamine 2 |
| PRSS53 | protease, serine, 53 |
| RAB40A | RAB40A, member RAS oncogene family |
| RAPSN | receptor-associated protein of the synapse |
| RGCC | regulator of cell cycle |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SCIN | scinderin |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIX3 | SIX homeobox 3 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSBP3 | single stranded DNA binding protein 3 |
| STEAP4 | STEAP family member 4 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TBC1D22B | TBC1 domain family, member 22B |
| TLN1 | talin 1 |
| TRAIP | TRAF interacting protein |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA3C | tubulin, alpha 3c |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| ZNF280B | zinc finger protein 280B |
| ZNF76 | zinc finger protein 76 |
