| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the letrozole-4824 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| AHI1 | Abelson helper integration site 1 |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ARF1 | ADP-ribosylation factor 1 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A |
| BMP5 | bone morphogenetic protein 5 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CALU | calumenin |
| CAPN7 | calpain 7 |
| CAPRIN1 | cell cycle associated protein 1 |
| CCNE2 | cyclin E2 |
| CDK2 | cyclin-dependent kinase 2 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| COMMD10 | COMM domain containing 10 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DTNA | dystrobrevin, alpha |
| ELK1 | ELK1, member of ETS oncogene family |
| ENO1 | enolase 1, (alpha) |
| FAS | Fas cell surface death receptor |
| FH | fumarate hydratase |
| FKBP1A | FK506 binding protein 1A, 12kDa |
| GDI2 | GDP dissociation inhibitor 2 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HOXA4 | homeobox A4 |
| HSF1 | heat shock transcription factor 1 |
| HSPA4 | heat shock 70kDa protein 4 |
| IDS | iduronate 2-sulfatase |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFT27 | intraflagellar transport 27 |
| IL17RC | interleukin 17 receptor C |
| ITGA6 | integrin, alpha 6 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLF4 | Kruppel-like factor 4 (gut) |
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
| LPIN1 | lipin 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MST1 | macrophage stimulating 1 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| NADK | NAD kinase |
| NLE1 | notchless homolog 1 (Drosophila) |
| NOTCH2 | notch 2 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| OCRL | oculocerebrorenal syndrome of Lowe |
| PARVA | parvin, alpha |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PCNX | pecanex homolog (Drosophila) |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PIGO | phosphatidylinositol glycan anchor biosynthesis, class O |
| POT1 | protection of telomeres 1 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PRPF4B | pre-mRNA processing factor 4B |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB35 | RAB35, member RAS oncogene family |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RNF122 | ring finger protein 122 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SEC23A | Sec23 homolog A (S. cerevisiae) |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPAG9 | sperm associated antigen 9 |
| SQLE | squalene epoxidase |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| SSBP2 | single-stranded DNA binding protein 2 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TBC1D5 | TBC1 domain family, member 5 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TFDP1 | transcription factor Dp-1 |
| TM2D1 | TM2 domain containing 1 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TOX4 | TOX high mobility group box family member 4 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) |
| VAMP3 | vesicle-associated membrane protein 3 |
| WDR1 | WD repeat domain 1 |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| WWOX | WW domain containing oxidoreductase |
| YIPF4 | Yip1 domain family, member 4 |
| ZMYND11 | zinc finger, MYND-type containing 11 |
| ZNF589 | zinc finger protein 589 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACPP | acid phosphatase, prostate |
| AFAP1 | actin filament associated protein 1 |
| ALPK1 | alpha-kinase 1 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CDON | cell adhesion associated, oncogene regulated |
| CEP97 | centrosomal protein 97kDa |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CORT | cortistatin |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| EDAR | ectodysplasin A receptor |
| EMID1 | EMI domain containing 1 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERCC2 | excision repair cross-complementation group 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM120C | family with sequence similarity 120C |
| FAM131A | family with sequence similarity 131, member A |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXO46 | F-box protein 46 |
| FLCN | folliculin |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FLJ22184 | |
| GRPR | gastrin-releasing peptide receptor |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H4D | histone cluster 1, H4d |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HMOX1 | heme oxygenase 1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| INO80D | INO80 complex subunit D |
| JMJD4 | jumonji domain containing 4 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIF13A | kinesin family member 13A |
| KLF13 | Kruppel-like factor 13 |
| KLHL29 | kelch-like family member 29 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LOXL3 | lysyl oxidase-like 3 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LTC4S | leukotriene C4 synthase |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MBTD1 | mbt domain containing 1 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MTSS1L | metastasis suppressor 1-like |
| MUC3B | mucin 3B, cell surface associated |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OLFML2A | olfactomedin-like 2A |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PRSS53 | protease, serine, 53 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RIN2 | Ras and Rab interactor 2 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF2 | ring finger protein 2 |
| RNF43 | ring finger protein 43 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPL10L | ribosomal protein L10-like |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCHIP1 | schwannomin interacting protein 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SPIDR | scaffolding protein involved in DNA repair |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCP10 | t-complex 10 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TLR5 | toll-like receptor 5 |
| TMEM212 | transmembrane protein 212 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TNS2 | tensin 2 |
| TPCN1 | two pore segment channel 1 |
| UBTD1 | ubiquitin domain containing 1 |
| UPK2 | uroplakin 2 |
| USB1 | U6 snRNA biogenesis 1 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF134 | zinc finger protein 134 |
| ZNF365 | zinc finger protein 365 |
| ZNF580 | zinc finger protein 580 |
| ZNF721 | zinc finger protein 721 |
| ZNF747 | zinc finger protein 747 |
