| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the letrozole-7336 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| B9D2 | B9 protein domain 2 |
| BBS9 | Bardet-Biedl syndrome 9 |
| BMP1 | bone morphogenetic protein 1 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) |
| CCNT2 | cyclin T2 |
| CDC25A | cell division cycle 25A |
| CDK10 | cyclin-dependent kinase 10 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 |
| CRYGC | crystallin, gamma C |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| EVA1B | eva-1 homolog B (C. elegans) |
| EXPH5 | exophilin 5 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| FZD7 | frizzled class receptor 7 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNRHR | gonadotropin-releasing hormone receptor |
| GON4L | gon-4-like (C. elegans) |
| GPR3 | G protein-coupled receptor 3 |
| GSPT1 | G1 to S phase transition 1 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HFE | hemochromatosis |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M |
| HOXC8 | homeobox C8 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IQCK | IQ motif containing K |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAGEA3 | melanoma antigen family A3 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MED16 | mediator complex subunit 16 |
| MGAT3 | mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MMP25 | matrix metallopeptidase 25 |
| NADK | NAD kinase |
| NCKAP1 | NCK-associated protein 1 |
| NF1 | neurofibromin 1 |
| PALM | paralemmin |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PAPPA2 | pappalysin 2 |
| PLCE1 | phospholipase C, epsilon 1 |
| PLIN2 | perilipin 2 |
| PLSCR3 | phospholipid scramblase 3 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PRLR | prolactin receptor |
| PRPF18 | pre-mRNA processing factor 18 |
| PXN | paxillin |
| RAD51 | RAD51 recombinase |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RB1 | retinoblastoma 1 |
| RND1 | Rho family GTPase 1 |
| RPL13 | ribosomal protein L13 |
| S100A8 | S100 calcium binding protein A8 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SC5D | sterol-C5-desaturase |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SIRT5 | sirtuin 5 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SMR3B | submaxillary gland androgen regulated protein 3B |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SRCAP | Snf2-related CREBBP activator protein |
| SUGP1 | SURP and G patch domain containing 1 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| THBS3 | thrombospondin 3 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TTC28 | tetratricopeptide repeat domain 28 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| UROD | uroporphyrinogen decarboxylase |
| VEGFA | vascular endothelial growth factor A |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ALPK1 | alpha-kinase 1 |
| ANKRD36 | ankyrin repeat domain 36 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| APH1B | APH1B gamma secretase subunit |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARRB2 | arrestin, beta 2 |
| AXIN1 | axin 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CEP97 | centrosomal protein 97kDa |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHST10 | carbohydrate sulfotransferase 10 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLSPN | claspin |
| CUEDC1 | CUE domain containing 1 |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FAM63A | family with sequence similarity 63, member A |
| FBXO31 | F-box protein 31 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FZD4 | frizzled class receptor 4 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GLI3 | GLI family zinc finger 3 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPC3 | glypican 3 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H3B | histone cluster 1, H3b |
| HMOX1 | heme oxygenase 1 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL15RA | interleukin 15 receptor, alpha |
| IL4R | interleukin 4 receptor |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| JRKL | JRK-like |
| KIAA0355 | KIAA0355 |
| KLHL21 | kelch-like family member 21 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LAMA3 | laminin, alpha 3 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC100287590 | uncharacterized LOC100287590 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRRC61 | leucine rich repeat containing 61 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MNS1 | meiosis-specific nuclear structural 1 |
| MOSPD3 | motile sperm domain containing 3 |
| NBEAL2 | neurobeachin-like 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NHLRC2 | NHL repeat containing 2 |
| NLK | nemo-like kinase |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NRSN2 | neurensin 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| POLH | polymerase (DNA directed), eta |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PRSS22 | protease, serine, 22 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIN2 | Ras and Rab interactor 2 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SALL2 | spalt-like transcription factor 2 |
| SCAI | suppressor of cancer cell invasion |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SDC3 | syndecan 3 |
| SH2D4A | SH2 domain containing 4A |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPIDR | scaffolding protein involved in DNA repair |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| SYT17 | synaptotagmin XVII |
| TAOK1 | TAO kinase 1 |
| TDRD1 | tudor domain containing 1 |
| TMEM209 | transmembrane protein 209 |
| TNS2 | tensin 2 |
| TRAIP | TRAF interacting protein |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WWC2 | WW and C2 domain containing 2 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF250 | zinc finger protein 250 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
