leucovorin Gene Set
Genes
8 genes differentially expressed following the leucovorin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RRP8
|
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
|
4.17252
|
|
CASK
|
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
|
3.66539
|
|
SLC35F2
|
solute carrier family 35, member F2
|
3.34586
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
3.04296
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PRORP
|
protein only RNase P catalytic subunit
|
-3.40082
|
|
OR3A2
|
olfactory receptor, family 3, subfamily A, member 2
|
-3.22963
|
|
NOS3
|
nitric oxide synthase 3 (endothelial cell)
|
-3.20227
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.20216
|