leukocyte Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Any of the blood cells that are colorless, lack hemoglobin, contain a nucleus, and include the lymphocytes, monocytes, neutrophils, eosinophils, and basophils. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000751)
Similar Terms
Downloads & Tools

Genes

339 genes co-occuring with the biological term leukocyte in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE2 angiotensin I converting enzyme 2
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACKR2 atypical chemokine receptor 2
ACTN1 actinin, alpha 1
ACTN4 actinin, alpha 4
ADAM10 ADAM metallopeptidase domain 10
ADAM15 ADAM metallopeptidase domain 15
ADAM17 ADAM metallopeptidase domain 17
ADAM28 ADAM metallopeptidase domain 28
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADGRE5 adhesion G protein-coupled receptor E5
ADGRG6 adhesion G protein-coupled receptor G6
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB2 adrenoceptor beta 2, surface
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
ALCAM activated leukocyte cell adhesion molecule
AMICA1 adhesion molecule, interacts with CXADR antigen 1
ANXA1 annexin A1
ANXA8 annexin A8
AOC3 amine oxidase, copper containing 3
APOE apolipoprotein E
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
AZU1 azurocidin 1
BACE1 beta-site APP-cleaving enzyme 1
BDKRB1 bradykinin receptor B1
BSG basigin (Ok blood group)
BTC betacellulin
CALR calreticulin
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CCL7 chemokine (C-C motif) ligand 7
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR4 chemokine (C-C motif) receptor 4
CD14 CD14 molecule
CD1B CD1b molecule
CD300LF CD300 molecule-like family member f
CD36 CD36 molecule (thrombospondin receptor)
CD38 CD38 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD47 CD47 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD80 CD80 molecule
CD83 CD83 molecule
CD9 CD9 molecule
CD93 CD93 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CERK ceramide kinase
CFB complement factor B
CFP complement factor properdin
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRM3 cholinergic receptor, muscarinic 3
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CIITA class II, major histocompatibility complex, transactivator
COMT catechol-O-methyltransferase
CORO1A coronin, actin binding protein, 1A
CPB2 carboxypeptidase B2 (plasma)
CPN1 carboxypeptidase N, polypeptide 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRP C-reactive protein, pentraxin-related
CRYAB crystallin, alpha B
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSK c-src tyrosine kinase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTSG cathepsin G
CTSS cathepsin S
CTTN cortactin
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2
CYTH1 cytohesin 1
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
ENG endoglin
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EZR ezrin
F11R F11 receptor
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FCAR Fc fragment of IgA receptor
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FERMT3 fermitin family member 3
FGD2 FYVE, RhoGEF and PH domain containing 2
FLT4 fms-related tyrosine kinase 4
FMNL1 formin-like 1
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
FPR3 formyl peptide receptor 3
GATA3 GATA binding protein 3
GLA galactosidase, alpha
GLUD1 glutamate dehydrogenase 1
GNAS GNAS complex locus
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPSM1 G-protein signaling modulator 1
GRK6 G protein-coupled receptor kinase 6
GRN granulin
GTDC1 glycosyltransferase-like domain containing 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAVCR2 hepatitis A virus cellular receptor 2
HCK HCK proto-oncogene, Src family tyrosine kinase
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-E major histocompatibility complex, class I, E
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ICAM1 intercellular adhesion molecule 1
ICAM3 intercellular adhesion molecule 3
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IDO1 indoleamine 2,3-dioxygenase 1
IDUA iduronidase, alpha-L-
IER3IP1 immediate early response 3 interacting protein 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL12A interleukin 12A
IL15 interleukin 15
IL17A interleukin 17A
IL18 interleukin 18
IL1B interleukin 1, beta
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL6 interleukin 6
ILK integrin-linked kinase
INS insulin
INSR insulin receptor
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK2 Janus kinase 2
JAM3 junctional adhesion molecule 3
JUN jun proto-oncogene
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KL klotho
KLF2 Kruppel-like factor 2
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMP2 lysosomal-associated membrane protein 2
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LCN2 lipocalin 2
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LDB2 LIM domain binding 2
LECT2 leukocyte cell-derived chemotaxin 2
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS2 lectin, galactoside-binding, soluble, 2
LGALS4 lectin, galactoside-binding, soluble, 4
LGALS9 lectin, galactoside-binding, soluble, 9
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LYZ lysozyme
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MAST4 microtubule associated serine/threonine kinase family member 4
MBOAT7 membrane bound O-acyltransferase domain containing 7
MIR31 microRNA 31
MLANA melan-A
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MSN moesin
MYH9 myosin, heavy chain 9, non-muscle
NCF1 neutrophil cytosolic factor 1
NCF1C neutrophil cytosolic factor 1C pseudogene
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH4 notch 4
NOX1 NADPH oxidase 1
NPPB natriuretic peptide B
NPPC natriuretic peptide C
NPY neuropeptide Y
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NSF N-ethylmaleimide-sensitive factor
NT5E 5'-nucleotidase, ecto (CD73)
NTN1 netrin 1
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OSMR oncostatin M receptor
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PADI2 peptidyl arginine deiminase, type II
PARVG parvin, gamma
PDIA2 protein disulfide isomerase family A, member 2
PECAM1 platelet/endothelial cell adhesion molecule 1
PI3 peptidase inhibitor 3, skin-derived
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAUR plasminogen activator, urokinase receptor
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PLG plasminogen
PLVAP plasmalemma vesicle associated protein
POMC proopiomelanocortin
PON1 paraoxonase 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRKCA protein kinase C, alpha
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTHLH parathyroid hormone-like hormone
PTK2B protein tyrosine kinase 2 beta
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRJ protein tyrosine phosphatase, receptor type, J
RAP1A RAP1A, member of RAS oncogene family
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP4 retinol binding protein 4, plasma
RDX radixin
RGMA repulsive guidance molecule family member a
RHOG ras homolog family member G
RLN1 relaxin 1
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROPN1 rhophilin associated tail protein 1
RXFP1 relaxin/insulin-like family peptide receptor 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SAA1 serum amyloid A1
SDC3 syndecan 3
SELE selectin E
SELL selectin L
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SFTPD surfactant protein D
SH3BP2 SH3-domain binding protein 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIGLEC5 sialic acid binding Ig-like lectin 5
SIPA1 signal-induced proliferation-associated 1
SIRPA signal-regulatory protein alpha
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLPI secretory leukocyte peptidase inhibitor
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNX20 sorting nexin 20
SOD1 superoxide dismutase 1, soluble
SPHK1 sphingosine kinase 1
SPN sialophorin
SPP1 secreted phosphoprotein 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STAB1 stabilin 1
SYK spleen tyrosine kinase
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TBX21 T-box 21
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
THY1 Thy-1 cell surface antigen
TLN1 talin 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TP53 tumor protein p53
TRIO trio Rho guanine nucleotide exchange factor
TXN thioredoxin
TXNIP thioredoxin interacting protein
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UMOD uromodulin
VCAM1 vascular cell adhesion molecule 1
VCAN versican
VCL vinculin
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VWF von Willebrand factor
WDR26 WD repeat domain 26
XCL1 chemokine (C motif) ligand 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XRN2 5'-3' exoribonuclease 2