leukoencephalopathy Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description This term describes abnormality of the white matter of the cerebrum resulting from damage to the myelin sheaths of nerve cells. (Human Phenotype Ontology, HP_0002352)
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Genes

33 genes co-occuring with the biological term leukoencephalopathy in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AARS2 alanyl-tRNA synthetase 2, mitochondrial
APOPT1 apoptogenic 1, mitochondrial
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CLCN2 chloride channel, voltage-sensitive 2
CSF1R colony stimulating factor 1 receptor
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
EARS2 glutamyl-tRNA synthetase 2, mitochondrial
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
GCDH glutaryl-CoA dehydrogenase
HEPACAM hepatic and glial cell adhesion molecule
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HTRA1 HtrA serine peptidase 1
JAG1 jagged 1
LMNB1 lamin B1
LPA lipoprotein, Lp(a)
MARS2 methionyl-tRNA synthetase 2, mitochondrial
MCL1 myeloid cell leukemia 1
MECP2 methyl CpG binding protein 2
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
NOTCH3 notch 3
PDCD1 programmed cell death 1
POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
RNASET2 ribonuclease T2
SDHAF1 succinate dehydrogenase complex assembly factor 1
SELL selectin L
TUBB4A tubulin, beta 4A class IVa
XCL1 chemokine (C motif) ligand 1