leukotriene biosynthetic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid. (Gene Ontology, GO_0019370)
External Link http://amigo.geneontology.org/amigo/term/GO:0019370
Similar Terms
Downloads & Tools

Genes

18 genes participating in the leukotriene biosynthetic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
GGT1 gamma-glutamyltransferase 1
GGT5 gamma-glutamyltransferase 5
GGT6 gamma-glutamyltransferase 6
GGT7 gamma-glutamyltransferase 7
GGTA1 glycoprotein alpha-galactosyltransferase 1 (inactive)
GGTLC1 gamma-glutamyltransferase light chain 1
GGTLC2 gamma-glutamyltransferase light chain 2
GGTLC3 gamma-glutamyltransferase light chain 3
LTA4H leukotriene A4 hydrolase
LTC4S leukotriene C4 synthase
MGST2 microsomal glutathione S-transferase 2
MGST3 microsomal glutathione S-transferase 3
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G5 phospholipase A2, group V