levallorphan-tartrate Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

632 genes differentially expressed following the levallorphan-tartrate small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
WDR7 WD repeat domain 7 6.38383
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 5.83926
GULP1 GULP, engulfment adaptor PTB domain containing 1 5.82713
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 5.46367
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 5.38876
FMNL1 formin-like 1 5.36589
DCLRE1B DNA cross-link repair 1B 5.25719
HAT1 histone acetyltransferase 1 5.11624
GIPR gastric inhibitory polypeptide receptor 5.09145
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 5.08049
TFEC transcription factor EC 5.05423
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 5.04801
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 4.97506
LALBA lactalbumin, alpha- 4.94803
TRIM36 tripartite motif containing 36 4.87152
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 4.8028
NHEJ1 nonhomologous end-joining factor 1 4.79949
PEPD peptidase D 4.77556
CD320 CD320 molecule 4.75652
RETREG1 reticulophagy regulator 1 4.75263
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 4.74923
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 4.66204
ERCC4 excision repair cross-complementation group 4 4.59919
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 4.58202
ETV1 ets variant 1 4.58006
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 4.56424
MEGF9 multiple EGF-like-domains 9 4.54125
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 4.53505
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10 4.53249
TFB1M transcription factor B1, mitochondrial 4.52613
TBP TATA box binding protein 4.48444
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 4.4819
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 4.44704
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 4.44464
MKKS McKusick-Kaufman syndrome 4.4103
CCNE2 cyclin E2 4.39176
FSTL4 follistatin-like 4 4.38528
LGALS13 lectin, galactoside-binding, soluble, 13 4.38229
ZNF556 zinc finger protein 556 4.38125
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 4.37826
MTUS2 microtubule associated tumor suppressor candidate 2 4.35788
GRN granulin 4.31247
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 4.30752
TSKS testis-specific serine kinase substrate 4.30392
CSN3 casein kappa 4.28719
SF3B4 splicing factor 3b, subunit 4, 49kDa 4.28525
ZNF271P zinc finger protein 271, pseudogene 4.24445
PARM1 prostate androgen-regulated mucin-like protein 1 4.23607
CPNE1 copine I 4.21817
TCIM transcriptional and immune response regulator 4.20408
DAP death-associated protein 4.17796
TBC1D22B TBC1 domain family, member 22B 4.17721
CSN2 casein beta 4.17004
CRYGB crystallin, gamma B 4.16282
PPP4R4 protein phosphatase 4, regulatory subunit 4 4.13257
CLSTN2 calsyntenin 2 4.12996
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 4.12596
FSD1 fibronectin type III and SPRY domain containing 1 4.12242
FAM124B family with sequence similarity 124B 4.11682
CSN1S1 casein alpha s1 4.10752
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 4.10323
GPR75 G protein-coupled receptor 75 4.0847
MTARC1 mitochondrial amidoxime reducing component 1 4.07991
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 4.06571
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 4.05903
TGIF2 TGFB-induced factor homeobox 2 4.03773
CDCA4 cell division cycle associated 4 4.02241
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 4.01624
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 4.01207
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 4.0059
SHROOM2 shroom family member 2 4.00072
MYL10 myosin, light chain 10, regulatory 3.9718
PRKCH protein kinase C, eta 3.9704
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 3.92939
TARBP1 TAR (HIV-1) RNA binding protein 1 3.91654
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 3.90566
YIPF2 Yip1 domain family, member 2 3.9051
TGM4 transglutaminase 4 3.89827
PCDHA9 protocadherin alpha 9 3.88929
ZSWIM1 zinc finger, SWIM-type containing 1 3.86401
TSPAN1 tetraspanin 1 3.86305
CRYAA crystallin, alpha A 3.86126
IRAK3 interleukin-1 receptor-associated kinase 3 3.85229
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 3.84537
COA7 cytochrome c oxidase assembly factor 7 (putative) 3.83526
MERTK MER proto-oncogene, tyrosine kinase 3.83001
ACAT2 acetyl-CoA acetyltransferase 2 3.81892
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 3.8144
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 3.80917
GYG1 glycogenin 1 3.80491
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 3.78593
ZXDC ZXD family zinc finger C 3.78431
MPST mercaptopyruvate sulfurtransferase 3.78069
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2 3.7805
RPP38 ribonuclease P/MRP 38kDa subunit 3.7648
PDK3 pyruvate dehydrogenase kinase, isozyme 3 3.73929
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 3.73661
MAST4 microtubule associated serine/threonine kinase family member 4 3.73643
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae) 3.7312
TSHZ2 teashirt zinc finger homeobox 2 3.73003
FBXL18 F-box and leucine-rich repeat protein 18 3.72952
PSKH1 protein serine kinase H1 3.7171
IBSP integrin-binding sialoprotein 3.71065
KIF24 kinesin family member 24 3.71018
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 3.70256
KALRN kalirin, RhoGEF kinase 3.6992
NRDE2 NRDE-2, necessary for RNA interference, domain containing 3.69613
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like 3.69026
MON1B MON1 secretory trafficking family member B 3.68327
FNDC3B fibronectin type III domain containing 3B 3.67637
GPR15 G protein-coupled receptor 15 3.66966
UTRN utrophin 3.66236
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 3.66174
RIPOR2 RHO family interacting cell polarization regulator 2 3.66124
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 3.65285
STAP2 signal transducing adaptor family member 2 3.63596
SNCA synuclein, alpha (non A4 component of amyloid precursor) 3.63297
SNHG32 small nucleolar RNA host gene 32 3.63029
GTPBP8 GTP-binding protein 8 (putative) 3.6265
C2 complement component 2 3.62108
RFX1 regulatory factor X, 1 (influences HLA class II expression) 3.61393
NUCB2 nucleobindin 2 3.60882
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 3.58746
FGF23 fibroblast growth factor 23 3.58588
SIX1 SIX homeobox 1 3.57706
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 3.57455
ANKRD28 ankyrin repeat domain 28 3.57347
VANGL1 VANGL planar cell polarity protein 1 3.57212
LINC00667 long intergenic non-protein coding RNA 667 3.56391
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 3.56084
EHD3 EH-domain containing 3 3.5599
FMO4 flavin containing monooxygenase 4 3.55621
ACTR5 ARP5 actin-related protein 5 homolog (yeast) 3.5562
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 3.54676
PKM pyruvate kinase, muscle 3.54192
SCAMP2 secretory carrier membrane protein 2 3.54073
CUBN cubilin (intrinsic factor-cobalamin receptor) 3.53612
GBX1 gastrulation brain homeobox 1 3.53407
PDCD2 programmed cell death 2 3.53207
ZNF573 zinc finger protein 573 3.52825
TYMS thymidylate synthetase 3.52385
RGS3 regulator of G-protein signaling 3 3.51605
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 3.5129
KLK3 kallikrein-related peptidase 3 3.49876
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 3.49547
CYCS cytochrome c, somatic 3.4927
SLC26A2 solute carrier family 26 (anion exchanger), member 2 3.48347
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 3.47864
C6ORF62 chromosome 6 open reading frame 62 3.47543
PDZK1 PDZ domain containing 1 3.47266
GYPA glycophorin A (MNS blood group) 3.47213
PRUNE1 prune exopolyphosphatase 1 3.4694
EFNA1 ephrin-A1 3.45635
TRIM68 tripartite motif containing 68 3.45363
LOX lysyl oxidase 3.4464
TFF1 trefoil factor 1 3.44377
MICA MHC class I polypeptide-related sequence A 3.43584
RRAGD Ras-related GTP binding D 3.4285
DUT deoxyuridine triphosphatase 3.42752
RNF122 ring finger protein 122 3.42418
SAA3P serum amyloid A3 pseudogene 3.42408
SP140 SP140 nuclear body protein 3.41574
PDZD7 PDZ domain containing 7 3.41504
MPHOSPH8 M-phase phosphoprotein 8 3.41373
CALHM2 calcium homeostasis modulator 2 3.40916
EXOSC1 exosome component 1 3.39902
CYBRD1 cytochrome b reductase 1 3.39826
FASTKD5 FAST kinase domains 5 3.39608
PADI4 peptidyl arginine deiminase, type IV 3.39214
CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13 3.38574
CHSY1 chondroitin sulfate synthase 1 3.38138
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 3.37296
MPIG6B megakaryocyte and platelet inhibitory receptor G6b 3.36797
VRTN vertebrae development associated 3.3678
CGREF1 cell growth regulator with EF-hand domain 1 3.36712
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 3.36303
TRIM21 tripartite motif containing 21 3.35777
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 3.35556
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 3.35235
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 3.35163
TSPO2 translocator protein 2 3.34991
SFRP4 secreted frizzled-related protein 4 3.34736
TAAR5 trace amine associated receptor 5 3.34559
LDHC lactate dehydrogenase C 3.34426
SCTR secretin receptor 3.3401
ARG2 arginase 2 3.33577
RHCE Rh blood group, CcEe antigens 3.33432
AMPD1 adenosine monophosphate deaminase 1 3.32778
MTMR12 myotubularin related protein 12 3.32582
CLDN7 claudin 7 3.32552
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 3.32251
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 3.32004
DOK3 docking protein 3 3.31939
FANCA Fanconi anemia, complementation group A 3.31731
CCDC70 coiled-coil domain containing 70 3.31726
GPR137 G protein-coupled receptor 137 3.31564
DOC2B double C2-like domains, beta 3.31036
DIRAS3 DIRAS family, GTP-binding RAS-like 3 3.30976
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 3.3086
FRZB frizzled-related protein 3.30855
NKX3-1 NK3 homeobox 1 3.30782
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 3.30666
MAVS mitochondrial antiviral signaling protein 3.30499
AP5S1 adaptor-related protein complex 5, sigma 1 subunit 3.30324
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 3.29877
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 3.29211
NAP1L4 nucleosome assembly protein 1-like 4 3.29112
KIF17 kinesin family member 17 3.28589
PRIM1 primase, DNA, polypeptide 1 (49kDa) 3.28454
TTLL7 tubulin tyrosine ligase-like family member 7 3.28399
RNF167 ring finger protein 167 3.28226
OR10H2 olfactory receptor, family 10, subfamily H, member 2 3.27169
PPP1R9A protein phosphatase 1, regulatory subunit 9A 3.26191
OR3A1 olfactory receptor, family 3, subfamily A, member 1 3.25955
MAP2K1 mitogen-activated protein kinase kinase 1 3.25662
ICOS inducible T-cell co-stimulator 3.24851
NMRK1 nicotinamide riboside kinase 1 3.24687
TRPM8 transient receptor potential cation channel, subfamily M, member 8 3.23683
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 3.23555
EGFL7 EGF-like-domain, multiple 7 3.23435
MAN1A1 mannosidase, alpha, class 1A, member 1 3.23234
ZXDB zinc finger, X-linked, duplicated B 3.23126
YBX2 Y box binding protein 2 3.22943
AMPD2 adenosine monophosphate deaminase 2 3.22409
IQGAP2 IQ motif containing GTPase activating protein 2 3.22192
DDO D-aspartate oxidase 3.22029
ZDHHC14 zinc finger, DHHC-type containing 14 3.2194
PCNA proliferating cell nuclear antigen 3.21787
TMBIM1 transmembrane BAX inhibitor motif containing 1 3.21472
NCLN nicalin 3.21262
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 3.20947
LRP3 low density lipoprotein receptor-related protein 3 3.20493
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 3.20467
XKR8 XK, Kell blood group complex subunit-related family, member 8 3.20354
PIM2 Pim-2 proto-oncogene, serine/threonine kinase 3.20342
OLFM1 olfactomedin 1 3.20022
FOCAD focadhesin 3.19951
GSS glutathione synthetase 3.19865
PLCB2 phospholipase C, beta 2 3.19432
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B 3.19135
SYNE3 spectrin repeat containing, nuclear envelope family member 3 3.18845
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 3.18714
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 3.18217
SPHK2 sphingosine kinase 2 3.1821
LMTK1 lemur tail kinase 1 3.18102
BCL7A B-cell CLL/lymphoma 7A 3.18064
RGS14 regulator of G-protein signaling 14 3.18024
ALPL alkaline phosphatase, liver/bone/kidney 3.17651
NEB nebulin 3.17229
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 3.15869
MCM3AP-AS1 MCM3AP antisense RNA 1 3.15093
BICDL1 BICD family like cargo adaptor 1 3.14279
EFNA4 ephrin-A4 3.13896
ARID3B AT rich interactive domain 3B (BRIGHT-like) 3.13848
CAPN3 calpain 3, (p94) 3.13587
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 3.13113
GPR45 G protein-coupled receptor 45 3.11445
ENTREP2 endosomal transmembrane epsin interactor 2 3.11365
TMEM168 transmembrane protein 168 3.11337
RAB29 RAB29, member RAS oncogene family 3.11251
MIR22HG MIR22 host gene 3.1105
FAF1 Fas (TNFRSF6) associated factor 1 3.10765
MTSS1 metastasis suppressor 1 3.10682
PDK1 pyruvate dehydrogenase kinase, isozyme 1 3.10385
C1ORF56 chromosome 1 open reading frame 56 3.1006
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21 3.09644
CCT2 chaperonin containing TCP1, subunit 2 (beta) 3.09118
FAM222B family with sequence similarity 222, member B 3.08887
RNF114 ring finger protein 114 3.0882
CCT4 chaperonin containing TCP1, subunit 4 (delta) 3.08573
ELP1 elongator acetyltransferase complex subunit 1 3.08432
S1PR4 sphingosine-1-phosphate receptor 4 3.08292
NOL10 nucleolar protein 10 3.08099
PCDHA6 protocadherin alpha 6 3.07568
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 3.07237
QTRT1 queuine tRNA-ribosyltransferase 1 3.07164
PLA2G10 phospholipase A2, group X 3.07138
PRAMEF10 PRAME family member 10 3.06825
H1-6 H1.6 linker histone, cluster member 3.06639
GPA33 glycoprotein A33 (transmembrane) 3.06074
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 3.05809
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 3.05808
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa 3.05652
CARTPT CART prepropeptide 3.05576
SLF2 SMC5-SMC6 complex localization factor 2 3.0552
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 3.05518
VLDLR very low density lipoprotein receptor 3.0537
RHAG Rh-associated glycoprotein 3.05018
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 3.04975
WASHC4 WASH complex subunit 4 3.04436
TPBG trophoblast glycoprotein 3.04336
PRM2 protamine 2 3.04235
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 3.04046
SRSF5 serine/arginine-rich splicing factor 5 3.03794
FAM13C family with sequence similarity 13, member C 3.03587
CCN2 cellular communication network factor 2 3.03359
FABP1 fatty acid binding protein 1, liver 3.03205
NCF4 neutrophil cytosolic factor 4, 40kDa 3.02105
LGALS3 lectin, galactoside-binding, soluble, 3 3.02046
GFRA1 GDNF family receptor alpha 1 3.02045
ZNF165 zinc finger protein 165 3.01801
RAB22A RAB22A, member RAS oncogene family 3.01763
ATP5F1A ATP synthase F1 subunit alpha 3.01662
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 3.01633
SLCO5A1 solute carrier organic anion transporter family, member 5A1 3.01568
LHFPL2 lipoma HMGIC fusion partner-like 2 3.01185
CDV3 CDV3 homolog (mouse) 3.00822
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 3.00712
AKAP4 A kinase (PRKA) anchor protein 4 3.00401
KLF11 Kruppel-like factor 11 3.00131

decreased expression

Symbol Name Standardized Value
TERT telomerase reverse transcriptase -9.08471
SCEL sciellin -6.44074
SPOP speckle-type POZ protein -6.38907
COL4A6 collagen, type IV, alpha 6 -6.11982
DZIP1 DAZ interacting zinc finger protein 1 -5.77372
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II -5.4905
PSORS1C2 psoriasis susceptibility 1 candidate 2 -5.39511
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -5.34586
BCL7B B-cell CLL/lymphoma 7B -5.34254
TCL1B T-cell leukemia/lymphoma 1B -5.29726
NUP62CL nucleoporin 62kDa C-terminal like -5.28249
SYNM synemin, intermediate filament protein -5.26539
JPT2 Jupiter microtubule associated homolog 2 -5.24196
PSG2 pregnancy specific beta-1-glycoprotein 2 -5.23139
ANXA10 annexin A10 -5.0991
HYAL4 hyaluronoglucosaminidase 4 -5.05071
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) -4.95104
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -4.88784
RPS5 ribosomal protein S5 -4.85326
FAM149A family with sequence similarity 149, member A -4.82343
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) -4.78297
IDE insulin-degrading enzyme -4.77651
VASH1 vasohibin 1 -4.7412
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -4.72886
KRTAP1-1 keratin associated protein 1-1 -4.72193
LCE2B late cornified envelope 2B -4.70514
EI24 etoposide induced 2.4 -4.70349
HOXC4 homeobox C4 -4.68549
BTNL2 butyrophilin-like 2 -4.66679
DSP desmoplakin -4.66569
ANXA13 annexin A13 -4.62879
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) -4.59106
NSUN5 NOP2/Sun domain family, member 5 -4.51976
MTMR1 myotubularin related protein 1 -4.50742
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 -4.49724
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 -4.47912
PSME3IP1 proteasome activator subunit 3 interacting protein 1 -4.40251
KDM3B lysine (K)-specific demethylase 3B -4.33576
FXYD2 FXYD domain containing ion transport regulator 2 -4.33266
MTSS2 MTSS I-BAR domain containing 2 -4.32646
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 -4.32045
MRE11 MRE11 homolog, double strand break repair nuclease -4.29994
POPDC2 popeye domain containing 2 -4.29814
HMGB1 high mobility group box 1 -4.29676
DIPK1A divergent protein kinase domain 1A -4.2946
TRAPPC2 trafficking protein particle complex 2 -4.29348
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled -4.29329
NT5C3A 5'-nucleotidase, cytosolic IIIA -4.28855
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -4.28626
HLA-F-AS1 HLA-F antisense RNA 1 -4.28586
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -4.27636
ZNHIT1 zinc finger, HIT-type containing 1 -4.26372
USH1C Usher syndrome 1C (autosomal recessive, severe) -4.23478
ADGRL1 adhesion G protein-coupled receptor L1 -4.22592
TCL1A T-cell leukemia/lymphoma 1A -4.21178
NRXN2 neurexin 2 -4.20501
TMX2 thioredoxin-related transmembrane protein 2 -4.19716
LIMS2 LIM and senescent cell antigen-like domains 2 -4.18154
CST6 cystatin E/M -4.16934
FRG1 FSHD region gene 1 -4.16749
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) -4.1494
FGB fibrinogen beta chain -4.14106
RAD51AP1 RAD51 associated protein 1 -4.13381
PHACTR1 phosphatase and actin regulator 1 -4.11595
TRAPPC11 trafficking protein particle complex 11 -4.10843
NPR2 natriuretic peptide receptor 2 -4.09926
MED4 mediator complex subunit 4 -4.09776
COPZ2 coatomer protein complex, subunit zeta 2 -4.09622
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -4.0946
CDSN corneodesmosin -4.09192
RAMP3 receptor (G protein-coupled) activity modifying protein 3 -4.08878
FAM131B family with sequence similarity 131, member B -4.0707
RAB26 RAB26, member RAS oncogene family -4.06626
UBE2M ubiquitin-conjugating enzyme E2M -4.06595
VWA1 von Willebrand factor A domain containing 1 -4.05181
CDC16 cell division cycle 16 -4.0413
FAM168A family with sequence similarity 168, member A -4.03656
CUL4B cullin 4B -4.03334
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa -4.0294
CRIPT cysteine-rich PDZ-binding protein -4.02849
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -4.02276
OPN3 opsin 3 -4.01009
JCAD junctional cadherin 5 associated -4.00309
TRPS1 trichorhinophalangeal syndrome I -3.99346
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 -3.98947
RAB6A RAB6A, member RAS oncogene family -3.98246
CDH13 cadherin 13 -3.97292
PCCA propionyl CoA carboxylase, alpha polypeptide -3.95882
KLK13 kallikrein-related peptidase 13 -3.94584
SAR1A secretion associated, Ras related GTPase 1A -3.93639
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 -3.92251
TM4SF4 transmembrane 4 L six family member 4 -3.91818
ELOB elongin B -3.91388
ERCC5 excision repair cross-complementation group 5 -3.91169
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 -3.90142
KRT9 keratin 9, type I -3.88198
FUBP3 far upstream element (FUSE) binding protein 3 -3.88037
MDH2 malate dehydrogenase 2, NAD (mitochondrial) -3.87907
NEUROD1 neuronal differentiation 1 -3.86488
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -3.86424
RFC3 replication factor C (activator 1) 3, 38kDa -3.86107
RPS19 ribosomal protein S19 -3.84772
SULF1 sulfatase 1 -3.84581
C1ORF68 chromosome 1 open reading frame 68 -3.83787
BLNK B-cell linker -3.83351
DLX6 distal-less homeobox 6 -3.82905
CEP57 centrosomal protein 57kDa -3.82814
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 -3.82305
NCOA3 nuclear receptor coactivator 3 -3.81825
SRC SRC proto-oncogene, non-receptor tyrosine kinase -3.81443
QPCT glutaminyl-peptide cyclotransferase -3.79358
ADGRG6 adhesion G protein-coupled receptor G6 -3.79248
IK IK cytokine, down-regulator of HLA II -3.79238
STEEP1 STING1 ER exit protein 1 -3.78344
USP25 ubiquitin specific peptidase 25 -3.77816
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.76876
SIRT3 sirtuin 3 -3.76657
TBL2 transducin (beta)-like 2 -3.76327
HOXA2 homeobox A2 -3.75721
DDIT3 DNA-damage-inducible transcript 3 -3.75594
NOL8 nucleolar protein 8 -3.7521
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 -3.75118
KAT7 K(lysine) acetyltransferase 7 -3.74874
ACKR2 atypical chemokine receptor 2 -3.74447
AFD1 acrofacial dysostosis 1, Nager type -3.73944
CCDC88A coiled-coil domain containing 88A -3.72011
TCF4 transcription factor 4 -3.7077
EXPH5 exophilin 5 -3.70487
MYO16 myosin XVI -3.70246
OBI1 ORC ubiquitin ligase 1 -3.69038
NAXD NAD(P)HX dehydratase -3.6902
MARCHF6 membrane associated ring-CH-type finger 6 -3.68552
HOXB9 homeobox B9 -3.68429
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 -3.6782
ANO10 anoctamin 10 -3.67691
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit -3.67355
BCL2L2 BCL2-like 2 -3.67109
KIF11 kinesin family member 11 -3.65732
GRSF1 G-rich RNA sequence binding factor 1 -3.65069
PPP1R13B protein phosphatase 1, regulatory subunit 13B -3.6445
BEAN1 brain expressed, associated with NEDD4, 1 -3.62999
DYNC2I1 dynein 2 intermediate chain 1 -3.62862
KLK10 kallikrein-related peptidase 10 -3.62571
SPAG16 sperm associated antigen 16 -3.60907
CASD1 CAS1 domain containing 1 -3.59647
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) -3.5922
ACAA1 acetyl-CoA acyltransferase 1 -3.59212
SLC30A5 solute carrier family 30 (zinc transporter), member 5 -3.59168
KCNK7 potassium channel, two pore domain subfamily K, member 7 -3.58763
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) -3.58626
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) -3.58605
MSL3 male-specific lethal 3 homolog (Drosophila) -3.58219
SLURP1 secreted LY6/PLAUR domain containing 1 -3.56951
BORA bora, aurora kinase A activator -3.56887
ZNF423 zinc finger protein 423 -3.56026
NACA nascent polypeptide-associated complex alpha subunit -3.55992
TAS2R13 taste receptor, type 2, member 13 -3.55739
RPL4 ribosomal protein L4 -3.55587
LINC01565 long intergenic non-protein coding RNA 1565 -3.55308
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -3.54171
BAHCC1 BAH domain and coiled-coil containing 1 -3.52598
MIR124-1HG MIR124-1 host gene -3.51432
NR2F1 nuclear receptor subfamily 2, group F, member 1 -3.50737
GPATCH8 G patch domain containing 8 -3.50649
RGS7 regulator of G-protein signaling 7 -3.50183
ASIC1 acid sensing (proton gated) ion channel 1 -3.4987
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 -3.49644
QRICH1 glutamine-rich 1 -3.48992
PIH1D1 PIH1 domain containing 1 -3.47948
ADCY3 adenylate cyclase 3 -3.46695
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -3.4629
HOXC10 homeobox C10 -3.44804
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit -3.44735
NGDN neuroguidin, EIF4E binding protein -3.43828
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 -3.43819
ZNF451 zinc finger protein 451 -3.43138
PSG5 pregnancy specific beta-1-glycoprotein 5 -3.42781
KIF21B kinesin family member 21B -3.42659
PEX5 peroxisomal biogenesis factor 5 -3.42067
RUBCNL rubicon like autophagy enhancer -3.41662
PGAP1 post-GPI attachment to proteins 1 -3.416
IRGQ immunity-related GTPase family, Q -3.41123
NCR3 natural cytotoxicity triggering receptor 3 -3.40829
FAM136A family with sequence similarity 136, member A -3.40623
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 -3.4043
MYT1 myelin transcription factor 1 -3.39774
BAIAP2L2 BAI1-associated protein 2-like 2 -3.39339
LORICRIN loricrin cornified envelope precursor protein -3.37418
PCID2 PCI domain containing 2 -3.37021
MT4 metallothionein 4 -3.36631
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -3.36586
PKD1 polycystic kidney disease 1 (autosomal dominant) -3.36425
MPDZ multiple PDZ domain protein -3.3636
BMP4 bone morphogenetic protein 4 -3.35628
DCAF13 DDB1 and CUL4 associated factor 13 -3.35612
MARCKS myristoylated alanine-rich protein kinase C substrate -3.35382
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -3.34771
LEF1 lymphoid enhancer-binding factor 1 -3.3453
ERBB4 erb-b2 receptor tyrosine kinase 4 -3.33038
SAP18 Sin3A-associated protein, 18kDa -3.32869
CLDN18 claudin 18 -3.32466
FGG fibrinogen gamma chain -3.32295
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 -3.32144
PRKD1 protein kinase D1 -3.32124
MTREX Mtr4 exosome RNA helicase -3.32083
VIPR1 vasoactive intestinal peptide receptor 1 -3.31607
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -3.31548
OFD1 oral-facial-digital syndrome 1 -3.31347
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa -3.3099
TMEM156 transmembrane protein 156 -3.29966
NOTCH4 notch 4 -3.29472
IRAK1 interleukin-1 receptor-associated kinase 1 -3.28902
SLITRK2 SLIT and NTRK-like family, member 2 -3.28765
PAX5 paired box 5 -3.28742
PLA2G2F phospholipase A2, group IIF -3.28709
STYXL1 serine/threonine/tyrosine interacting-like 1 -3.28606
EXOSC8 exosome component 8 -3.28488
E4F1 E4F transcription factor 1 -3.28034
KRT38 keratin 38, type I -3.28031
MANSC1 MANSC domain containing 1 -3.27722
UFC1 ubiquitin-fold modifier conjugating enzyme 1 -3.27658
MYD88 myeloid differentiation primary response 88 -3.27554
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -3.27194
SCUBE3 signal peptide, CUB domain, EGF-like 3 -3.26975
VTCN1 V-set domain containing T cell activation inhibitor 1 -3.26689
CRCT1 cysteine-rich C-terminal 1 -3.2636
FAT4 FAT atypical cadherin 4 -3.26244
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -3.26
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -3.25837
SPRY2 sprouty homolog 2 (Drosophila) -3.25533
FGF7 fibroblast growth factor 7 -3.25212
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) -3.24331
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -3.24093
WNT5A wingless-type MMTV integration site family, member 5A -3.22541
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic -3.224
ANO1 anoctamin 1, calcium activated chloride channel -3.21574
COMMD9 COMM domain containing 9 -3.21476
BUD31 BUD31 homolog (S. cerevisiae) -3.20297
MZF1 myeloid zinc finger 1 -3.20288
AFAP1 actin filament associated protein 1 -3.19606
NSUN5P1 NOP2/Sun domain family, member 5 pseudogene 1 -3.19239
RIT2 Ras-like without CAAX 2 -3.19065
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme -3.18769
NBN nibrin -3.18713
NPEPL1 aminopeptidase-like 1 -3.18503
LCK LCK proto-oncogene, Src family tyrosine kinase -3.17732
PPARD peroxisome proliferator-activated receptor delta -3.1706
GADD45B growth arrest and DNA-damage-inducible, beta -3.1666
GHITM growth hormone inducible transmembrane protein -3.15682
BIRC7 baculoviral IAP repeat containing 7 -3.15393
ZNF506 zinc finger protein 506 -3.15097
GPR20 G protein-coupled receptor 20 -3.14717
EPN2 epsin 2 -3.14503
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase -3.14449
CACNB2 calcium channel, voltage-dependent, beta 2 subunit -3.14137
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -3.14104
LIPF lipase, gastric -3.13475
CRYGA crystallin, gamma A -3.13426
TUBGCP3 tubulin, gamma complex associated protein 3 -3.13375
WDR91 WD repeat domain 91 -3.13213
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -3.13129
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) -3.12772
PARVA parvin, alpha -3.12062
NKAPD1 NKAP domain containing 1 -3.11591
EMP2 epithelial membrane protein 2 -3.11588
RIMS1 regulating synaptic membrane exocytosis 1 -3.11366
USP39 ubiquitin specific peptidase 39 -3.11253
SRR serine racemase -3.10984
ULBP1 UL16 binding protein 1 -3.10495
DHRS3 dehydrogenase/reductase (SDR family) member 3 -3.10454
SKI SKI proto-oncogene -3.10257
IRF8 interferon regulatory factor 8 -3.10186
RAB40B RAB40B, member RAS oncogene family -3.0987
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) -3.09819
DUSP2 dual specificity phosphatase 2 -3.09745
SLC26A10P solute carrier family 26 member 10, pseudogene -3.0958
SKP1 S-phase kinase-associated protein 1 -3.09297
POF1B premature ovarian failure, 1B -3.09208
WNT3 wingless-type MMTV integration site family, member 3 -3.08507
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -3.08386
ATM ATM serine/threonine kinase -3.08289
ENDOU endonuclease, polyU-specific -3.08221
DSC1 desmocollin 1 -3.06624
GPM6B glycoprotein M6B -3.06301
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) -3.05878
EIF3H eukaryotic translation initiation factor 3, subunit H -3.05864
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -3.05827
FANCC Fanconi anemia, complementation group C -3.05791
IFNAR1 interferon (alpha, beta and omega) receptor 1 -3.05622
EREG epiregulin -3.05352
RGS11 regulator of G-protein signaling 11 -3.04991
MICALL1 MICAL-like 1 -3.04778
NTM neurotrimin -3.04751
RAMP2 receptor (G protein-coupled) activity modifying protein 2 -3.0461
RTF2 replication termination factor 2 -3.04551
TP53BP1 tumor protein p53 binding protein 1 -3.04451
CXXC4 CXXC finger protein 4 -3.03972
EPHX3 epoxide hydrolase 3 -3.03362
POGLUT2 protein O-glucosyltransferase 2 -3.03248
UNC5C unc-5 homolog C (C. elegans) -3.03017
TELO2 telomere maintenance 2 -3.02915
DMWD dystrophia myotonica, WD repeat containing -3.02879
KCMF1 potassium channel modulatory factor 1 -3.02716
DSG1 desmoglein 1 -3.02649
TFCP2 transcription factor CP2 -3.02178
PLK3 polo-like kinase 3 -3.02079
S100A7 S100 calcium binding protein A7 -3.02046
CCR7 chemokine (C-C motif) receptor 7 -3.02034
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 -3.02004
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -3.01577
ENOX1 ecto-NOX disulfide-thiol exchanger 1 -3.0156
CLCA2 chloride channel accessory 2 -3.01511
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) -3.01481
SCIN scinderin -3.01296
HNF4G hepatocyte nuclear factor 4, gamma -3.01162
SS18L2 synovial sarcoma translocation gene on chromosome 18-like 2 -3.01092
SERHL2 serine hydrolase-like 2 -3.00962
RNF170 ring finger protein 170 -3.00619
C12ORF4 chromosome 12 open reading frame 4 -3.0053
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa -3.00311
DNAH17 dynein, axonemal, heavy chain 17 -3.00247
MTMR7 myotubularin related protein 7 -3.00011