levamisole-2257 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the levamisole-2257 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ACBD4 acyl-CoA binding domain containing 4
ACTC1 actin, alpha, cardiac muscle 1
ACVR1B activin A receptor, type IB
AKAP13 A kinase (PRKA) anchor protein 13
ANGPTL2 angiopoietin-like 2
AQP3 aquaporin 3 (Gill blood group)
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BEST2 bestrophin 2
C21ORF2 chromosome 21 open reading frame 2
CA9 carbonic anhydrase IX
CAPN9 calpain 9
CCL19 chemokine (C-C motif) ligand 19
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD3D CD3d molecule, delta (CD3-TCR complex)
CD79B CD79b molecule, immunoglobulin-associated beta
COL6A1 collagen, type VI, alpha 1
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CSF1R colony stimulating factor 1 receptor
CST8 cystatin 8 (cystatin-related epididymal specific)
CTIF CBP80/20-dependent translation initiation factor
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DBP D site of albumin promoter (albumin D-box) binding protein
DNASE2B deoxyribonuclease II beta
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ETV5 ets variant 5
ETV7 ets variant 7
EXPH5 exophilin 5
FAM110B family with sequence similarity 110, member B
FBLN1 fibulin 1
FOLR2 folate receptor 2 (fetal)
FRMPD1 FERM and PDZ domain containing 1
FST follistatin
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GJA8 gap junction protein, alpha 8, 50kDa
GLS glutaminase
GM2A GM2 ganglioside activator
GRIK1 glutamate receptor, ionotropic, kainate 1
GRM7 glutamate receptor, metabotropic 7
HBEGF heparin-binding EGF-like growth factor
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIPK3 homeodomain interacting protein kinase 3
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HLF hepatic leukemia factor
IL36G interleukin 36, gamma
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB1BP2 integrin beta 1 binding protein (melusin) 2
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIF25 kinesin family member 25
KLHL25 kelch-like family member 25
KLK8 kallikrein-related peptidase 8
LDLR low density lipoprotein receptor
LHX1 LIM homeobox 1
LMAN1 lectin, mannose-binding, 1
MBNL1 muscleblind-like splicing regulator 1
MINK1 misshapen-like kinase 1
MRC2 mannose receptor, C type 2
MTL5 metallothionein-like 5, testis-specific (tesmin)
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NPR1 natriuretic peptide receptor 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR6A1 nuclear receptor subfamily 6, group A, member 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDE10A phosphodiesterase 10A
PDE4DIP phosphodiesterase 4D interacting protein
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKP2 plakophilin 2
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PQLC3 PQ loop repeat containing 3
PRKCI protein kinase C, iota
REPS1 RALBP1 associated Eps domain containing 1
RHBG Rh family, B glycoprotein (gene/pseudogene)
RHEB Ras homolog enriched in brain
SAP30 Sin3A-associated protein, 30kDa
SCD5 stearoyl-CoA desaturase 5
SDC2 syndecan 2
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SH2D3A SH2 domain containing 3A
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SNAP25 synaptosomal-associated protein, 25kDa
SRGN serglycin
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TP53I11 tumor protein p53 inducible protein 11
TPO thyroid peroxidase
USB1 U6 snRNA biogenesis 1
ZEB1 zinc finger E-box binding homeobox 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZFP64 ZFP64 zinc finger protein
ZNF304 zinc finger protein 304

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADM adrenomedullin
AES amino-terminal enhancer of split
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARHGAP4 Rho GTPase activating protein 4
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASAP1-IT1 ASAP1 intronic transcript 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAHCC1 BAH domain and coiled-coil containing 1
C17ORF70 chromosome 17 open reading frame 70
C22ORF46 chromosome 22 open reading frame 46
C3 complement component 3
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAPN15 calpain 15
CD82 CD82 molecule
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
DGAT1 diacylglycerol O-acyltransferase 1
DNAH17 dynein, axonemal, heavy chain 17
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EFNA3 ephrin-A3
FADS2 fatty acid desaturase 2
FAM155B family with sequence similarity 155, member B
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FHOD1 formin homology 2 domain containing 1
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GMEB1 glucocorticoid modulatory element binding protein 1
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRPR gastrin-releasing peptide receptor
HIST1H1D histone cluster 1, H1d
HIST1H2BJ histone cluster 1, H2bj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA4 homeobox A4
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCTD7 potassium channel tetramerization domain containing 7
KIAA0894 KIAA0894 protein
KLHL28 kelch-like family member 28
KRT24 keratin 24, type I
LAMB3 laminin, beta 3
LINC00597 long intergenic non-protein coding RNA 597
LRRC49 leucine rich repeat containing 49
MEFV Mediterranean fever
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MVP major vault protein
MXD3 MAX dimerization protein 3
NIPAL2 NIPA-like domain containing 2
NR1D2 nuclear receptor subfamily 1, group D, member 2
NXPH4 neurexophilin 4
OSMR oncostatin M receptor
PCSK7 proprotein convertase subtilisin/kexin type 7
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLAC1 placenta-specific 1
PLD3 phospholipase D family, member 3
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
POMT2 protein-O-mannosyltransferase 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRDM16 PR domain containing 16
PTPRU protein tyrosine phosphatase, receptor type, U
PYHIN1 pyrin and HIN domain family, member 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASL11B RAS-like, family 11, member B
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RGS17 regulator of G-protein signaling 17
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP32 ribosomal protein L23a pseudogene 32
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RUNDC3B RUN domain containing 3B
S100A9 S100 calcium binding protein A9
SAYSD1 SAYSVFN motif domain containing 1
SETD1A SET domain containing 1A
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SKI SKI proto-oncogene
SMAD5 SMAD family member 5
SRPX sushi-repeat containing protein, X-linked
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TBC1D2 TBC1 domain family, member 2
TCHH trichohyalin
TIGD6 tigger transposable element derived 6
TM7SF3 transmembrane 7 superfamily member 3
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRPC5 transient receptor potential cation channel, subfamily C, member 5
UPP1 uridine phosphorylase 1
VGF VGF nerve growth factor inducible
VIM vimentin
XYLT2 xylosyltransferase II
YY2 YY2 transcription factor
ZIC3 Zic family member 3
ZNF10 zinc finger protein 10
ZNF136 zinc finger protein 136
ZNF324 zinc finger protein 324
ZNF37BP zinc finger protein 37B, pseudogene
ZNF611 zinc finger protein 611
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862