levobunolol-3354 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the levobunolol-3354 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AJAP1 adherens junctions associated protein 1
AKAP6 A kinase (PRKA) anchor protein 6
ALDOB aldolase B, fructose-bisphosphate
APOC1 apolipoprotein C-I
AQP3 aquaporin 3 (Gill blood group)
ARID1A AT rich interactive domain 1A (SWI-like)
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
C17ORF80 chromosome 17 open reading frame 80
C1ORF54 chromosome 1 open reading frame 54
C21ORF2 chromosome 21 open reading frame 2
CA5B carbonic anhydrase VB, mitochondrial
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDK12 cyclin-dependent kinase 12
CDK13 cyclin-dependent kinase 13
CERS4 ceramide synthase 4
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLCA1 chloride channel accessory 1
COL11A1 collagen, type XI, alpha 1
CREBBP CREB binding protein
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DFNB31 deafness, autosomal recessive 31
DLL3 delta-like 3 (Drosophila)
DSC2 desmocollin 2
ERCC2 excision repair cross-complementation group 2
ERP44 endoplasmic reticulum protein 44
FAM153A family with sequence similarity 153, member A
FOXG1 forkhead box G1
GK glycerol kinase
GPC3 glypican 3
GPR135 G protein-coupled receptor 135
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HEXA-AS1 HEXA antisense RNA 1
HMOX1 heme oxygenase 1
HOXA1 homeobox A1
HR hair growth associated
HSF1 heat shock transcription factor 1
IGFBP3 insulin-like growth factor binding protein 3
IL11RA interleukin 11 receptor, alpha
IL1RN interleukin 1 receptor antagonist
INHBA inhibin, beta A
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
JUN jun proto-oncogene
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KRT83 keratin 83, type II
LAT2 linker for activation of T cells family, member 2
LINC00652 long intergenic non-protein coding RNA 652
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAX MYC associated factor X
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
N4BP2L1 NEDD4 binding protein 2-like 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOX1 NADPH oxidase 1
NR2F1 nuclear receptor subfamily 2, group F, member 1
PARVB parvin, beta
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDLIM5 PDZ and LIM domain 5
PKNOX2 PBX/knotted 1 homeobox 2
PLA2G1B phospholipase A2, group IB (pancreas)
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPIA peptidylprolyl isomerase A (cyclophilin A)
PTDSS2 phosphatidylserine synthase 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTHLH parathyroid hormone-like hormone
RAB40C RAB40C, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAI2 retinoic acid induced 2
RETN resistin
RGS4 regulator of G-protein signaling 4
RHEB Ras homolog enriched in brain
RUNDC3A RUN domain containing 3A
SDS serine dehydratase
SECTM1 secreted and transmembrane 1
SERHL2 serine hydrolase-like 2
STOML1 stomatin (EPB72)-like 1
SUGP1 SURP and G patch domain containing 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYN2 synapsin II
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAT tyrosine aminotransferase
TBXA2R thromboxane A2 receptor
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TCP10 t-complex 10
TEP1 telomerase-associated protein 1
TF transferrin
THTPA thiamine triphosphatase
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TSPAN9 tetraspanin 9
USP22 ubiquitin specific peptidase 22
WDFY3 WD repeat and FYVE domain containing 3
WNT10B wingless-type MMTV integration site family, member 10B
WSB1 WD repeat and SOCS box containing 1
ZFHX4 zinc finger homeobox 4

decreased expression

Symbol Name
ACYP2 acylphosphatase 2, muscle type
ADAP2 ArfGAP with dual PH domains 2
ADTRP androgen-dependent TFPI-regulating protein
AGMAT agmatine ureohydrolase (agmatinase)
ALG12 ALG12, alpha-1,6-mannosyltransferase
APLP1 amyloid beta (A4) precursor-like protein 1
APOC4 apolipoprotein C-IV
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMCX2 armadillo repeat containing, X-linked 2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BGLAP bone gamma-carboxyglutamate (gla) protein
C17ORF53 chromosome 17 open reading frame 53
C19ORF73 chromosome 19 open reading frame 73
C1ORF105 chromosome 1 open reading frame 105
C2ORF27A chromosome 2 open reading frame 27A
C6ORF47 chromosome 6 open reading frame 47
CCDC121 coiled-coil domain containing 121
CD82 CD82 molecule
CLCN5 chloride channel, voltage-sensitive 5
CORO7 coronin 7
CTRL chymotrypsin-like
CUL9 cullin 9
CXADR coxsackie virus and adenovirus receptor
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DOC2A double C2-like domains, alpha
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
ENO3 enolase 3 (beta, muscle)
FAM53B family with sequence similarity 53, member B
FBXO2 F-box protein 2
FGD1 FYVE, RhoGEF and PH domain containing 1
FILIP1L filamin A interacting protein 1-like
GADD45G growth arrest and DNA-damage-inducible, gamma
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR27 G protein-coupled receptor 27
GREB1L growth regulation by estrogen in breast cancer-like
GSTTP1 glutathione S-transferase theta pseudogene 1
HOXA4 homeobox A4
HOXC8 homeobox C8
KCTD7 potassium channel tetramerization domain containing 7
KDM5C lysine (K)-specific demethylase 5C
LAMB3 laminin, beta 3
LAMP3 lysosomal-associated membrane protein 3
LIF leukemia inhibitory factor
LIG4 ligase IV, DNA, ATP-dependent
MAGEA6 melanoma antigen family A6
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAPK10 mitogen-activated protein kinase 10
MCOLN1 mucolipin 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTCP1 mature T-cell proliferation 1
MYOZ3 myozenin 3
N4BP3 NEDD4 binding protein 3
NPM3 nucleophosmin/nucleoplasmin 3
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OLFML2A olfactomedin-like 2A
PDE8B phosphodiesterase 8B
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
POPDC3 popeye domain containing 3
PSG4 pregnancy specific beta-1-glycoprotein 4
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RHOBTB2 Rho-related BTB domain containing 2
RNF146 ring finger protein 146
RNF208 ring finger protein 208
RNF43 ring finger protein 43
ROM1 retinal outer segment membrane protein 1
RRAGB Ras-related GTP binding B
SAYSD1 SAYSVFN motif domain containing 1
SDC3 syndecan 3
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SPON2 spondin 2, extracellular matrix protein
STK16 serine/threonine kinase 16
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBC1D2 TBC1 domain family, member 2
TCTN1 tectonic family member 1
TFF2 trefoil factor 2
THRAP3 thyroid hormone receptor associated protein 3
THRB thyroid hormone receptor, beta
TMEM180 transmembrane protein 180
TONSL tonsoku-like, DNA repair protein
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TRIM66 tripartite motif containing 66
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA3C tubulin, alpha 3c
VIPR1 vasoactive intestinal peptide receptor 1
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF124 zinc finger protein 124
ZNF134 zinc finger protein 134
ZNF358 zinc finger protein 358
ZNF37BP zinc finger protein 37B, pseudogene
ZNF442 zinc finger protein 442
ZNF446 zinc finger protein 446
ZNF747 zinc finger protein 747