levobunolol-4016 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

192 genes differentially expressed following the levobunolol-4016 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACSM3 acyl-CoA synthetase medium-chain family member 3
AGFG1 ArfGAP with FG repeats 1
AKAP5 A kinase (PRKA) anchor protein 5
AKR1C4 aldo-keto reductase family 1, member C4
ALK anaplastic lymphoma receptor tyrosine kinase
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C11ORF1 chromosome 11 open reading frame 1
CA5B carbonic anhydrase VB, mitochondrial
CCL23 chemokine (C-C motif) ligand 23
CDK20 cyclin-dependent kinase 20
CEP295 centrosomal protein 295kDa
CFLAR CASP8 and FADD-like apoptosis regulator
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLCN6 chloride channel, voltage-sensitive 6
CNOT4 CCR4-NOT transcription complex, subunit 4
CNTNAP2 contactin associated protein-like 2
CPB2 carboxypeptidase B2 (plasma)
CPEB3 cytoplasmic polyadenylation element binding protein 3
CRHR2 corticotropin releasing hormone receptor 2
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DPY19L1P1 DPY19L1 pseudogene 1
DSTYK dual serine/threonine and tyrosine protein kinase
EDNRA endothelin receptor type A
ERBB4 erb-b2 receptor tyrosine kinase 4
ETV1 ets variant 1
EXOC7 exocyst complex component 7
FAM63A family with sequence similarity 63, member A
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCF1 FCF1 rRNA-processing protein
FRMD4A FERM domain containing 4A
GLG1 golgi glycoprotein 1
HIPK3 homeodomain interacting protein kinase 3
HIST1H2BO histone cluster 1, H2bo
HIST1H4D histone cluster 1, H4d
HOMER3 homer scaffolding protein 3
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IL18R1 interleukin 18 receptor 1
ING4 inhibitor of growth family, member 4
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
LDB2 LIM domain binding 2
LOC157562 uncharacterized LOC157562
LRP1 low density lipoprotein receptor-related protein 1
LRRN3 leucine rich repeat neuronal 3
MAP2K5 mitogen-activated protein kinase kinase 5
MBTD1 mbt domain containing 1
MSLN mesothelin
NAV3 neuron navigator 3
NEK1 NIMA-related kinase 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NR1H4 nuclear receptor subfamily 1, group H, member 4
NRP1 neuropilin 1
NUPR1 nuclear protein, transcriptional regulator, 1
NXF2 nuclear RNA export factor 2
PDGFA platelet-derived growth factor alpha polypeptide
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PMP2 peripheral myelin protein 2
PNLIPRP2 pancreatic lipase-related protein 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRDM2 PR domain containing 2, with ZNF domain
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PRKCI protein kinase C, iota
PTBP3 polypyrimidine tract binding protein 3
PTPN12 protein tyrosine phosphatase, non-receptor type 12
R3HDM1 R3H domain containing 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RARG retinoic acid receptor, gamma
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS5 regulator of G-protein signaling 5
RPS4Y1 ribosomal protein S4, Y-linked 1
SGSM3 small G protein signaling modulator 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
STAT2 signal transducer and activator of transcription 2, 113kDa
STON1 stonin 1
STS steroid sulfatase (microsomal), isozyme S
SYCP2 synaptonemal complex protein 2
SYNJ1 synaptojanin 1
TADA2A transcriptional adaptor 2A
TBC1D22B TBC1 domain family, member 22B
TBC1D2B TBC1 domain family, member 2B
THBD thrombomodulin
TMC6 transmembrane channel-like 6
TMEM63A transmembrane protein 63A
TMPO thymopoietin
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNPO2 transportin 2
TRA2A transformer 2 alpha homolog (Drosophila)
TRIO trio Rho guanine nucleotide exchange factor
TUBA3C tubulin, alpha 3c
VCX2 variable charge, X-linked 2
WDR55 WD repeat domain 55
ZBED4 zinc finger, BED-type containing 4
ZCCHC11 zinc finger, CCHC domain containing 11
ZNF137P zinc finger protein 137, pseudogene
ZNF225 zinc finger protein 225
ZNF589 zinc finger protein 589
ZNF75D zinc finger protein 75D
ZNF839 zinc finger protein 839

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
AGMAT agmatine ureohydrolase (agmatinase)
ALOX15B arachidonate 15-lipoxygenase, type B
APOC4 apolipoprotein C-IV
ARC activity-regulated cytoskeleton-associated protein
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BDNF brain-derived neurotrophic factor
BST1 bone marrow stromal cell antigen 1
BTF3P11 basic transcription factor 3 pseudogene 11
C5ORF42 chromosome 5 open reading frame 42
C7ORF69 chromosome 7 open reading frame 69
CCDC71 coiled-coil domain containing 71
CD79B CD79b molecule, immunoglobulin-associated beta
CGA glycoprotein hormones, alpha polypeptide
CHI3L2 chitinase 3-like 2
CIDEB cell death-inducing DFFA-like effector b
CNGB3 cyclic nucleotide gated channel beta 3
COL9A3 collagen, type IX, alpha 3
CRLF1 cytokine receptor-like factor 1
CTSF cathepsin F
CUZD1 CUB and zona pellucida-like domains 1
DAGLA diacylglycerol lipase, alpha
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
EFNA3 ephrin-A3
ENO3 enolase 3 (beta, muscle)
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ERO1LB ERO1-like beta (S. cerevisiae)
FGF3 fibroblast growth factor 3
FLT4 fms-related tyrosine kinase 4
GPR21 G protein-coupled receptor 21
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRAMD1B GRAM domain containing 1B
GRM6 glutamate receptor, metabotropic 6
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
HIST1H2BM histone cluster 1, H2bm
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IGLL1 immunoglobulin lambda-like polypeptide 1
IL17RB interleukin 17 receptor B
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IQSEC2 IQ motif and Sec7 domain 2
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KDM5C lysine (K)-specific demethylase 5C
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA1456 KIAA1456
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIRREL kin of IRRE like (Drosophila)
KRT86 keratin 86, type II
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LMTK1 lemur tail kinase 1
LY6D lymphocyte antigen 6 complex, locus D
MAGEF1 melanoma antigen family F1
MNMIP1 manchette microtubule inner protein 1
MTSS1L metastasis suppressor 1-like
MX1 MX dynamin-like GTPase 1
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NIPAL2 NIPA-like domain containing 2
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
ONECUT2 one cut homeobox 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PALMD palmdelphin
PARD6A par-6 family cell polarity regulator alpha
PARP8 poly (ADP-ribose) polymerase family, member 8
PDE8B phosphodiesterase 8B
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLXNB3 plexin B3
POLL polymerase (DNA directed), lambda
PRB3 proline-rich protein BstNI subfamily 3
RAB36 RAB36, member RAS oncogene family
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF126P1 ring finger protein 126 pseudogene 1
RPP25 ribonuclease P/MRP 25kDa subunit
SAYSD1 SAYSVFN motif domain containing 1
SCGB2A2 secretoglobin, family 2A, member 2
SLC22A14 solute carrier family 22, member 14
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SSTR4 somatostatin receptor 4
STAB2 stabilin 2
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM212 transmembrane protein 212
TPCN1 two pore segment channel 1
TTLL1 tubulin tyrosine ligase-like family member 1
UNC13A unc-13 homolog A (C. elegans)
USP19 ubiquitin specific peptidase 19
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZNF222 zinc finger protein 222