| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the levobunolol-4134 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACPP | acid phosphatase, prostate |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADCK2 | aarF domain containing kinase 2 |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATN1 | atrophin 1 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide |
| ATXN2L | ataxin 2-like |
| BMP4 | bone morphogenetic protein 4 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CALML3 | calmodulin-like 3 |
| CARD10 | caspase recruitment domain family, member 10 |
| CARD14 | caspase recruitment domain family, member 14 |
| CD58 | CD58 molecule |
| CD8A | CD8a molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDK18 | cyclin-dependent kinase 18 |
| CDK2 | cyclin-dependent kinase 2 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLTA | clathrin, light chain A |
| COL1A1 | collagen, type I, alpha 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| ETV5 | ets variant 5 |
| FAM171A1 | family with sequence similarity 171, member A1 |
| FBXO2 | F-box protein 2 |
| FGF16 | fibroblast growth factor 16 |
| GDPD2 | glycerophosphodiester phosphodiesterase domain containing 2 |
| GHRHR | growth hormone releasing hormone receptor |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GPR15 | G protein-coupled receptor 15 |
| GPR85 | G protein-coupled receptor 85 |
| GYPB | glycophorin B (MNS blood group) |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M |
| HPX | hemopexin |
| HRH1 | histamine receptor H1 |
| IL2RB | interleukin 2 receptor, beta |
| KIAA1107 | KIAA1107 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT8 | keratin 8, type II |
| LIG3 | ligase III, DNA, ATP-dependent |
| LIMCH1 | LIM and calponin homology domains 1 |
| LIMK1 | LIM domain kinase 1 |
| LMF2 | lipase maturation factor 2 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MIP | major intrinsic protein of lens fiber |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MR1 | major histocompatibility complex, class I-related |
| MX2 | MX dynamin-like GTPase 2 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NCOR2 | nuclear receptor corepressor 2 |
| NPFF | neuropeptide FF-amide peptide precursor |
| OGG1 | 8-oxoguanine DNA glycosylase |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PLAC4 | placenta-specific 4 |
| PLLP | plasmolipin |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RECQL5 | RecQ protein-like 5 |
| RGS10 | regulator of G-protein signaling 10 |
| RHEB | Ras homolog enriched in brain |
| RIN1 | Ras and Rab interactor 1 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SAMD4A | sterile alpha motif domain containing 4A |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SERHL2 | serine hydrolase-like 2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SIK2 | salt-inducible kinase 2 |
| SLC39A9 | solute carrier family 39, member 9 |
| SOAT2 | sterol O-acyltransferase 2 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TBXA2R | thromboxane A2 receptor |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TLR2 | toll-like receptor 2 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TMOD1 | tropomodulin 1 |
| TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| UMPS | uridine monophosphate synthetase |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| ACTL8 | actin-like 8 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CBX8 | chromobox homolog 8 |
| CCDC130 | coiled-coil domain containing 130 |
| CCDC71 | coiled-coil domain containing 71 |
| CCDC9 | coiled-coil domain containing 9 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CD83 | CD83 molecule |
| CDHR2 | cadherin-related family member 2 |
| CHM | choroideremia (Rab escort protein 1) |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CLCA1 | chloride channel accessory 1 |
| CNTNAP1 | contactin associated protein 1 |
| CUEDC1 | CUE domain containing 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DENND5B | DENN/MADD domain containing 5B |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EN2 | engrailed homeobox 2 |
| EPX | eosinophil peroxidase |
| ERCC2 | excision repair cross-complementation group 2 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FUZ | fuzzy planar cell polarity protein |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GPR3 | G protein-coupled receptor 3 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC11 | histone deacetylase 11 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BN | histone cluster 1, H2bn |
| HMOX1 | heme oxygenase 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KRT83 | keratin 83, type II |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LTC4S | leukotriene C4 synthase |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NLRX1 | NLR family member X1 |
| NPY4R | neuropeptide Y receptor Y4 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCDHGB6 | protocadherin gamma subfamily B, 6 |
| PDE8B | phosphodiesterase 8B |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PROL1 | proline rich, lacrimal 1 |
| PRR14L | proline rich 14-like |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RFXAP | regulatory factor X-associated protein |
| RGS20 | regulator of G-protein signaling 20 |
| RLN1 | relaxin 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF122 | ring finger protein 122 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC16A4 | solute carrier family 16, member 4 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STAB2 | stabilin 2 |
| TBX19 | T-box 19 |
| TBX3 | T-box 3 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TEP1 | telomerase-associated protein 1 |
| TNS2 | tensin 2 |
| VASH1 | vasohibin 1 |
| VASP | vasodilator-stimulated phosphoprotein |
| VEGFB | vascular endothelial growth factor B |
| WDR78 | WD repeat domain 78 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF280A | zinc finger protein 280A |
| ZNF304 | zinc finger protein 304 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF41 | zinc finger protein 41 |
