levocabastine-2948 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the levocabastine-2948 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADTRP androgen-dependent TFPI-regulating protein
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ANKH ANKH inorganic pyrophosphate transport regulator
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APOC1 apolipoprotein C-I
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
BEGAIN brain-enriched guanylate kinase-associated
BEST1 bestrophin 1
BTN3A1 butyrophilin, subfamily 3, member A1
C3ORF18 chromosome 3 open reading frame 18
C3ORF52 chromosome 3 open reading frame 52
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CEP41 centrosomal protein 41kDa
CLCN4 chloride channel, voltage-sensitive 4
CNPY4 canopy FGF signaling regulator 4
COPZ2 coatomer protein complex, subunit zeta 2
CREM cAMP responsive element modulator
DCAF15 DDB1 and CUL4 associated factor 15
DEFB1 defensin, beta 1
DMRT1 doublesex and mab-3 related transcription factor 1
DVL1 dishevelled segment polarity protein 1
EED embryonic ectoderm development
EFNA3 ephrin-A3
EHD1 EH-domain containing 1
EMP1 epithelial membrane protein 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EXD3 exonuclease 3'-5' domain containing 3
EXOC7 exocyst complex component 7
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM214B family with sequence similarity 214, member B
FBXL18 F-box and leucine-rich repeat protein 18
FCAR Fc fragment of IgA receptor
FCMR Fc fragment of IgM receptor
FER fer (fps/fes related) tyrosine kinase
GABARAPL1 GABA(A) receptor-associated protein like 1
GFOD2 glucose-fructose oxidoreductase domain containing 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GM2A GM2 ganglioside activator
HDLBP high density lipoprotein binding protein
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HNMT histamine N-methyltransferase
HOXA5 homeobox A5
HYAL2 hyaluronoglucosaminidase 2
IMPG2 interphotoreceptor matrix proteoglycan 2
ING2 inhibitor of growth family, member 2
INPP5J inositol polyphosphate-5-phosphatase J
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KLHL28 kelch-like family member 28
KRT81 keratin 81, type II
LEFTY2 left-right determination factor 2
MAP3K7CL MAP3K7 C-terminal like
MCM3AP minichromosome maintenance complex component 3 associated protein
METRN meteorin, glial cell differentiation regulator
MR1 major histocompatibility complex, class I-related
MTCL1 microtubule crosslinking factor 1
MYOZ3 myozenin 3
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NPHP1 nephronophthisis 1 (juvenile)
PARP12 poly (ADP-ribose) polymerase family, member 12
PDLIM2 PDZ and LIM domain 2 (mystique)
PDLIM5 PDZ and LIM domain 5
PEX3 peroxisomal biogenesis factor 3
PIAS2 protein inhibitor of activated STAT, 2
PLCB2 phospholipase C, beta 2
PLCD1 phospholipase C, delta 1
PODNL1 podocan-like 1
PODXL2 podocalyxin-like 2
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PTEN phosphatase and tensin homolog
PYGB phosphorylase, glycogen; brain
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAD51B RAD51 paralog B
RASAL2 RAS protein activator like 2
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RTEL1 regulator of telomere elongation helicase 1
SCARB2 scavenger receptor class B, member 2
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SGSM3 small G protein signaling modulator 3
SLAMF7 SLAM family member 7
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SPINK5 serine peptidase inhibitor, Kazal type 5
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SV2C synaptic vesicle glycoprotein 2C
TAS2R1 taste receptor, type 2, member 1
TFEB transcription factor EB
TIGD6 tigger transposable element derived 6
TLDC1 TBC/LysM-associated domain containing 1
TMEM19 transmembrane protein 19
TRADD TNFRSF1A-associated via death domain
TRMT61A tRNA methyltransferase 61A
UCN urocortin
UGCG UDP-glucose ceramide glucosyltransferase
ZNF219 zinc finger protein 219
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
AIM2 absent in melanoma 2
ANKRD40 ankyrin repeat domain 40
ARMC7 armadillo repeat containing 7
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BAG4 BCL2-associated athanogene 4
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRPF1 bromodomain and PHD finger containing, 1
CDK3 cyclin-dependent kinase 3
CDKL3 cyclin-dependent kinase-like 3
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLGN calmegin
CMTR1 cap methyltransferase 1
COQ6 coenzyme Q6 monooxygenase
CORO7 coronin 7
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNMBP dynamin binding protein
DOLK dolichol kinase
DSE dermatan sulfate epimerase
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ERAL1 Era-like 12S mitochondrial rRNA chaperone 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGL2 fibrinogen-like 2
FHL3 four and a half LIM domains 3
FMO4 flavin containing monooxygenase 4
GEM GTP binding protein overexpressed in skeletal muscle
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GPATCH2 G patch domain containing 2
GPR27 G protein-coupled receptor 27
GSTM2 glutathione S-transferase mu 2 (muscle)
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HHLA3 HERV-H LTR-associating 3
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BJ histone cluster 1, H2bj
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific
HP haptoglobin
HSPA1L heat shock 70kDa protein 1-like
IFI6 interferon, alpha-inducible protein 6
IP6K1 inositol hexakisphosphate kinase 1
IRF2 interferon regulatory factor 2
IRF9 interferon regulatory factor 9
ISOC2 isochorismatase domain containing 2
JUNB jun B proto-oncogene
KCNK5 potassium channel, two pore domain subfamily K, member 5
KDM7A lysine (K)-specific demethylase 7A
KIF13B kinesin family member 13B
KPTN kaptin (actin binding protein)
LINS lines homolog (Drosophila)
LMNB2 lamin B2
LZTR1 leucine-zipper-like transcription regulator 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MMP2 matrix metallopeptidase 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL44 mitochondrial ribosomal protein L44
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MVD mevalonate (diphospho) decarboxylase
MX2 MX dynamin-like GTPase 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NABP2 nucleic acid binding protein 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NPIPB3 nuclear pore complex interacting protein family, member B3
NUBPL nucleotide binding protein-like
PECR peroxisomal trans-2-enoyl-CoA reductase
PGM1 phosphoglucomutase 1
PHACTR1 phosphatase and actin regulator 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PNPLA6 patatin-like phospholipase domain containing 6
POM121 POM121 transmembrane nucleoporin
POMZP3 POM121 and ZP3 fusion
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
RAB33B RAB33B, member RAS oncogene family
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF113A ring finger protein 113A
RNF122 ring finger protein 122
RPUSD2 RNA pseudouridylate synthase domain containing 2
RUSC2 RUN and SH3 domain containing 2
SCAMP4 secretory carrier membrane protein 4
SCD5 stearoyl-CoA desaturase 5
STBD1 starch binding domain 1
STX17 syntaxin 17
SYNC syncoilin, intermediate filament protein
THEM6 thioesterase superfamily member 6
TTC33 tetratricopeptide repeat domain 33
VASP vasodilator-stimulated phosphoprotein
WDR33 WD repeat domain 33
WDR44 WD repeat domain 44
XPC xeroderma pigmentosum, complementation group C
ZNF304 zinc finger protein 304
ZNF37BP zinc finger protein 37B, pseudogene
ZNF408 zinc finger protein 408
ZNF480 zinc finger protein 480
ZNF552 zinc finger protein 552
ZNF574 zinc finger protein 574