levocabastine-3509 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the levocabastine-3509 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA1 actin, alpha 1, skeletal muscle
AMOT angiomotin
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARMC4 armadillo repeat containing 4
ARPIN actin-related protein 2/3 complex inhibitor
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
C8ORF44 chromosome 8 open reading frame 44
CA4 carbonic anhydrase IV
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAPN9 calpain 9
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CD6 CD6 molecule
CD83 CD83 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CES3 carboxylesterase 3
CFLAR CASP8 and FADD-like apoptosis regulator
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLIC5 chloride intracellular channel 5
COPZ2 coatomer protein complex, subunit zeta 2
CRAT carnitine O-acetyltransferase
CRTC1 CREB regulated transcription coactivator 1
DBP D site of albumin promoter (albumin D-box) binding protein
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DICER1 dicer 1, ribonuclease type III
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOPEY2 dopey family member 2
EHF ets homologous factor
EMC3 ER membrane protein complex subunit 3
EXT1 exostosin glycosyltransferase 1
FADS2 fatty acid desaturase 2
FGFR1 fibroblast growth factor receptor 1
GJA4 gap junction protein, alpha 4, 37kDa
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSTP1 glutathione S-transferase pi 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H3F histone cluster 1, H3f
HMOX1 heme oxygenase 1
ID2B inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene)
IFT140 intraflagellar transport 140
IGHMBP2 immunoglobulin mu binding protein 2
INHBA inhibin, beta A
IRF4 interferon regulatory factor 4
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KANK1 KN motif and ankyrin repeat domains 1
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LAPTM5 lysosomal protein transmembrane 5
LMAN1 lectin, mannose-binding, 1
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MX2 MX dynamin-like GTPase 2
MYRF myelin regulatory factor
NF1 neurofibromin 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUP188 nucleoporin 188kDa
OGFR opioid growth factor receptor
PDCD6 programmed cell death 6
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHEX phosphate regulating endopeptidase homolog, X-linked
PPARA peroxisome proliferator-activated receptor alpha
PQBP1 polyglutamine binding protein 1
PXDC1 PX domain containing 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB6B RAB6B, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBM12B RNA binding motif protein 12B
RFXAP regulatory factor X-associated protein
RGS2 regulator of G-protein signaling 2
RRAGD Ras-related GTP binding D
S100A13 S100 calcium binding protein A13
SDC2 syndecan 2
SDC3 syndecan 3
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SEMG2 semenogelin II
SFTPD surfactant protein D
SKIL SKI-like proto-oncogene
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC25A30 solute carrier family 25, member 30
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SOX21 SRY (sex determining region Y)-box 21
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRSF6 serine/arginine-rich splicing factor 6
STK11 serine/threonine kinase 11
TLK1 tousled-like kinase 1
TMCC2 transmembrane and coiled-coil domain family 2
TMPRSS15 transmembrane protease, serine 15
TSSK2 testis-specific serine kinase 2
UNC93B1 unc-93 homolog B1 (C. elegans)
WSB1 WD repeat and SOCS box containing 1
ZNF358 zinc finger protein 358
ZNF44 zinc finger protein 44
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACSF2 acyl-CoA synthetase family member 2
ADCY6 adenylate cyclase 6
ADGRG2 adhesion G protein-coupled receptor G2
ALPK1 alpha-kinase 1
ARMC6 armadillo repeat containing 6
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP13A2 ATPase type 13A2
BAG4 BCL2-associated athanogene 4
BAHCC1 BAH domain and coiled-coil containing 1
BCORL1 BCL6 corepressor-like 1
BPGM 2,3-bisphosphoglycerate mutase
BTBD2 BTB (POZ) domain containing 2
BTD biotinidase
C14ORF93 chromosome 14 open reading frame 93
C19ORF73 chromosome 19 open reading frame 73
CBX4 chromobox homolog 4
CCP110 centriolar coiled coil protein 110kDa
CINP cyclin-dependent kinase 2 interacting protein
CORT cortistatin
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FBXL6 F-box and leucine-rich repeat protein 6
FCHO1 FCH domain only 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
FKBP5 FK506 binding protein 5
FLT4 fms-related tyrosine kinase 4
FUZ fuzzy planar cell polarity protein
GLB1L2 galactosidase, beta 1-like 2
GLI3 GLI family zinc finger 3
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HIST1H1D histone cluster 1, H1d
HIST2H2AA3 histone cluster 2, H2aa3
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSPA1L heat shock 70kDa protein 1-like
INCENP inner centromere protein antigens 135/155kDa
IP6K2 inositol hexakisphosphate kinase 2
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
L2HGDH L-2-hydroxyglutarate dehydrogenase
LAMA5 laminin, alpha 5
LARP6 La ribonucleoprotein domain family, member 6
LHX6 LIM homeobox 6
LOC730101 uncharacterized LOC730101
LRRC20 leucine rich repeat containing 20
LRRC61 leucine rich repeat containing 61
LY6G5C lymphocyte antigen 6 complex, locus G5C
LZTFL1 leucine zipper transcription factor-like 1
MAN2B1 mannosidase, alpha, class 2B, member 1
MANBA mannosidase, beta A, lysosomal
MAPKBP1 mitogen-activated protein kinase binding protein 1
METTL2B methyltransferase like 2B
MFAP2 microfibrillar-associated protein 2
MGC12488
MSRA methionine sulfoxide reductase A
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NES nestin
NPFFR1 neuropeptide FF receptor 1
NPTX1 neuronal pentraxin I
P3H1 prolyl 3-hydroxylase 1
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PLA2G3 phospholipase A2, group III
PLD3 phospholipase D family, member 3
PNPLA6 patatin-like phospholipase domain containing 6
POPDC3 popeye domain containing 3
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRSS22 protease, serine, 22
PTDSS2 phosphatidylserine synthase 2
PTK6 protein tyrosine kinase 6
QSER1 glutamine and serine rich 1
RASL11B RAS-like, family 11, member B
RNF25 ring finger protein 25
S100A4 S100 calcium binding protein A4
SIRT6 sirtuin 6
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
STX5 syntaxin 5
STXBP2 syntaxin binding protein 2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAOK1 TAO kinase 1
TDRD1 tudor domain containing 1
TICAM1 toll-like receptor adaptor molecule 1
TMEM115 transmembrane protein 115
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TTBK2 tau tubulin kinase 2
TUBA3D tubulin, alpha 3d
UBQLN4 ubiquilin 4
UBXN6 UBX domain protein 6
VAX2 ventral anterior homeobox 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YEATS2 YEATS domain containing 2
ZNF16 zinc finger protein 16
ZNF254 zinc finger protein 254
ZNF282 zinc finger protein 282
ZNF574 zinc finger protein 574