levocabastine-hcl Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

575 genes differentially expressed following the levocabastine-hcl small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CYCS cytochrome c, somatic 10.1318
ACAA1 acetyl-CoA acyltransferase 1 7.79083
DYNLT3 dynein, light chain, Tctex-type 3 7.77607
MOK MOK protein kinase 7.34023
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 6.905
CASP10 caspase 10, apoptosis-related cysteine peptidase 6.05735
GLDC glycine dehydrogenase (decarboxylating) 5.81523
TARBP1 TAR (HIV-1) RNA binding protein 1 5.71438
RIPK4 receptor-interacting serine-threonine kinase 4 5.03353
C1ORF116 chromosome 1 open reading frame 116 5.00142
AMD1 adenosylmethionine decarboxylase 1 4.88366
NAP1L3 nucleosome assembly protein 1-like 3 4.86411
IKZF1 IKAROS family zinc finger 1 (Ikaros) 4.85694
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 4.76239
FBXO2 F-box protein 2 4.72292
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 4.6768
PTPRG protein tyrosine phosphatase, receptor type, G 4.62878
IL12RB2 interleukin 12 receptor, beta 2 4.60562
GPX3 glutathione peroxidase 3 4.50297
CCR6 chemokine (C-C motif) receptor 6 4.4996
USP36 ubiquitin specific peptidase 36 4.47421
THEMIS2 thymocyte selection associated family member 2 4.44623
BHMT2 betaine--homocysteine S-methyltransferase 2 4.44205
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 4.439
TIAM1 T-cell lymphoma invasion and metastasis 1 4.40315
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 4.36173
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 4.33913
TFDP3 transcription factor Dp family, member 3 4.32938
TRPV2 transient receptor potential cation channel, subfamily V, member 2 4.32926
FGF18 fibroblast growth factor 18 4.29861
TASP1 taspase, threonine aspartase, 1 4.28965
OXT oxytocin/neurophysin I prepropeptide 4.2502
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 4.23147
RCAN3 RCAN family member 3 4.22931
DNAAF5 dynein, axonemal, assembly factor 5 4.22066
GPX7 glutathione peroxidase 7 4.2139
TERT telomerase reverse transcriptase 4.19063
EIF3B eukaryotic translation initiation factor 3, subunit B 4.16432
RHOD ras homolog family member D 4.15787
GAL3ST4 galactose-3-O-sulfotransferase 4 4.14536
DKK2 dickkopf WNT signaling pathway inhibitor 2 4.12424
TRIM38 tripartite motif containing 38 4.11806
CX3CR1 chemokine (C-X3-C motif) receptor 1 4.11765
EBLN2 endogenous Bornavirus-like nucleoprotein 2 4.10095
CDCA4 cell division cycle associated 4 4.09277
IQSEC3 IQ motif and Sec7 domain 3 4.09083
EPHX2 epoxide hydrolase 2, cytoplasmic 4.05778
FKBP9 FK506 binding protein 9, 63 kDa 4.05281
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 4.04744
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 4.03393
PTPN11 protein tyrosine phosphatase, non-receptor type 11 4.02879
BEX4 brain expressed, X-linked 4 4.02724
ISYNA1 inositol-3-phosphate synthase 1 4.01472
CP ceruloplasmin (ferroxidase) 3.95852
COPZ2 coatomer protein complex, subunit zeta 2 3.93651
AKAP7 A kinase (PRKA) anchor protein 7 3.92662
LHFPL6 LHFPL tetraspan subfamily member 6 3.88575
MFAP5 microfibrillar associated protein 5 3.88449
ADCY2 adenylate cyclase 2 (brain) 3.88013
AKAP13 A kinase (PRKA) anchor protein 13 3.87748
CHI3L2 chitinase 3-like 2 3.87003
ZNF134 zinc finger protein 134 3.86966
ADAM9 ADAM metallopeptidase domain 9 3.85883
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 3.85741
HCLS1 hematopoietic cell-specific Lyn substrate 1 3.84485
LLGL2 lethal giant larvae homolog 2 (Drosophila) 3.84262
NQO2 NAD(P)H dehydrogenase, quinone 2 3.8313
CPPED1 calcineurin-like phosphoesterase domain containing 1 3.8232
SEPTIN4 septin 4 3.82307
DLEC1 deleted in lung and esophageal cancer 1 3.81731
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 3.80379
CTNND1 catenin (cadherin-associated protein), delta 1 3.80064
PLA2G5 phospholipase A2, group V 3.79654
ANGPT1 angiopoietin 1 3.77138
EIF2D eukaryotic translation initiation factor 2D 3.76924
NOL11 nucleolar protein 11 3.76379
BAHCC1 BAH domain and coiled-coil containing 1 3.75646
CTNND2 catenin (cadherin-associated protein), delta 2 3.75244
SIRPB1 signal-regulatory protein beta 1 3.72966
SKI SKI proto-oncogene 3.72376
SORBS3 sorbin and SH3 domain containing 3 3.71117
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 3.70707
SELL selectin L 3.70205
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 3.69851
CPN1 carboxypeptidase N, polypeptide 1 3.68
C2CD2 C2 calcium-dependent domain containing 2 3.67921
CCDC86 coiled-coil domain containing 86 3.67867
TPPP3 tubulin polymerization-promoting protein family member 3 3.66655
SDC4 syndecan 4 3.6658
WBP4 WW domain binding protein 4 3.66477
PKNOX2 PBX/knotted 1 homeobox 2 3.63531
PAK1IP1 PAK1 interacting protein 1 3.6257
NOP53 NOP53 ribosome biogenesis factor 3.6177
CFAP45 cilia and flagella associated protein 45 3.60623
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 3.59865
GRHL2 grainyhead-like 2 (Drosophila) 3.58325
ZNF268 zinc finger protein 268 3.57985
FSTL1 follistatin-like 1 3.57651
TNPO1 transportin 1 3.56697
RPGR retinitis pigmentosa GTPase regulator 3.56409
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 3.56375
PUS1 pseudouridylate synthase 1 3.55623
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 3.54908
IL6R interleukin 6 receptor 3.54859
OPRK1 opioid receptor, kappa 1 3.54522
GCKR glucokinase (hexokinase 4) regulator 3.54456
CYB5R3 cytochrome b5 reductase 3 3.53037
NXF2 nuclear RNA export factor 2 3.52641
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 3.523
KIAA0319 KIAA0319 3.52294
SSH3 slingshot protein phosphatase 3 3.52281
ADRB2 adrenoceptor beta 2, surface 3.50596
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 3.50466
ELOVL2 ELOVL fatty acid elongase 2 3.49924
BST1 bone marrow stromal cell antigen 1 3.48763
FXYD6 FXYD domain containing ion transport regulator 6 3.48719
POMC proopiomelanocortin 3.48348
KAZN kazrin, periplakin interacting protein 3.47441
PLSCR3 phospholipid scramblase 3 3.47407
LDB1 LIM domain binding 1 3.47124
HLA-E major histocompatibility complex, class I, E 3.46696
GCGR glucagon receptor 3.4582
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 3.45003
LIMCH1 LIM and calponin homology domains 1 3.44515
ECM2 extracellular matrix protein 2, female organ and adipocyte specific 3.44297
EPCAM epithelial cell adhesion molecule 3.42588
ELP5 elongator acetyltransferase complex subunit 5 3.41872
EPHA1 EPH receptor A1 3.41823
TRAPPC4 trafficking protein particle complex 4 3.40774
ZNF606 zinc finger protein 606 3.40485
NLRP3 NLR family, pyrin domain containing 3 3.4027
SCRG1 stimulator of chondrogenesis 1 3.39382
ASIC2 acid sensing (proton gated) ion channel 2 3.38064
MAGEA8 melanoma antigen family A8 3.38048
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 3.37643
LGALS2 lectin, galactoside-binding, soluble, 2 3.3734
RNF122 ring finger protein 122 3.37265
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 3.36764
CCL20 chemokine (C-C motif) ligand 20 3.35641
SEPHS1 selenophosphate synthetase 1 3.35457
PHACTR2 phosphatase and actin regulator 2 3.3464
UBE4A ubiquitination factor E4A 3.345
AHR aryl hydrocarbon receptor 3.33693
ACVR1B activin A receptor, type IB 3.33549
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 3.32872
LZTFL1 leucine zipper transcription factor-like 1 3.32702
CHD1L chromodomain helicase DNA binding protein 1-like 3.29786
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 3.29553
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 3.29549
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 3.29409
FICD FIC domain containing 3.29137
PPP6R2 protein phosphatase 6, regulatory subunit 2 3.29058
SLC39A14 solute carrier family 39 (zinc transporter), member 14 3.28938
DLD dihydrolipoamide dehydrogenase 3.28127
SH2D1A SH2 domain containing 1A 3.27888
MPDZ multiple PDZ domain protein 3.27794
NAMPT nicotinamide phosphoribosyltransferase 3.27207
IL15RA interleukin 15 receptor, alpha 3.26866
ZNF83 zinc finger protein 83 3.26765
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 3.26557
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 3.25959
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 3.25358
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 3.24028
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 3.23799
CLDN7 claudin 7 3.23772
RGN regucalcin 3.22115
MR1 major histocompatibility complex, class I-related 3.22081
TSHB thyroid stimulating hormone, beta 3.21698
ATXN2 ataxin 2 3.2134
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1 3.21299
STK3 serine/threonine kinase 3 3.21234
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 3.21
ELN elastin 3.20463
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 3.20429
ANAPC1 anaphase promoting complex subunit 1 3.20214
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 3.19989
WASF3 WAS protein family, member 3 3.19935
EI24 etoposide induced 2.4 3.19705
PXDC1 PX domain containing 1 3.19692
ABLIM1 actin binding LIM protein 1 3.19577
SUN1 Sad1 and UNC84 domain containing 1 3.1956
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 3.19276
PUS3 pseudouridylate synthase 3 3.19089
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 3.18892
ACTR6 ARP6 actin-related protein 6 homolog (yeast) 3.18612
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 3.18127
RAD23A RAD23 homolog A (S. cerevisiae) 3.18114
MYO6 myosin VI 3.17729
LETM1 leucine zipper-EF-hand containing transmembrane protein 1 3.17684
COL8A2 collagen, type VIII, alpha 2 3.17673
C3 complement component 3 3.17594
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 3.17484
RABGGTB Rab geranylgeranyltransferase, beta subunit 3.17289
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 3.17077
FAM149A family with sequence similarity 149, member A 3.16646
SARS2 seryl-tRNA synthetase 2, mitochondrial 3.16602
NMT2 N-myristoyltransferase 2 3.16081
YME1L1 YME1-like 1 ATPase 3.159
KIF3B kinesin family member 3B 3.15824
CNKSR1 connector enhancer of kinase suppressor of Ras 1 3.15015
DNAI7 dynein axonemal intermediate chain 7 3.14715
S1PR1 sphingosine-1-phosphate receptor 1 3.14622
AEBP1 AE binding protein 1 3.14571
TJP2 tight junction protein 2 3.14351
QKI QKI, KH domain containing, RNA binding 3.13664
PLCB2 phospholipase C, beta 2 3.13652
ECHDC3 enoyl CoA hydratase domain containing 3 3.13513
GHRHR growth hormone releasing hormone receptor 3.126
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 3.12553
CHRD chordin 3.11824
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 3.116
ERBIN erbb2 interacting protein 3.11369
NT5E 5'-nucleotidase, ecto (CD73) 3.1118
PNPO pyridoxamine 5'-phosphate oxidase 3.11146
CLIC1 chloride intracellular channel 1 3.10774
PNKP polynucleotide kinase 3'-phosphatase 3.10718
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 3.10665
FADS1 fatty acid desaturase 1 3.09985
CSPG4 chondroitin sulfate proteoglycan 4 3.09757
SRPX2 sushi-repeat containing protein, X-linked 2 3.09572
FGFR3 fibroblast growth factor receptor 3 3.09444
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 3.09301
BLTP3B bridge-like lipid transfer protein family member 3B 3.09049
CPVL carboxypeptidase, vitellogenic-like 3.08837
SP140L SP140 nuclear body protein-like 3.08761
CD1D CD1d molecule 3.08623
UBTD1 ubiquitin domain containing 1 3.08297
TSC22D2 TSC22 domain family, member 2 3.07559
TMEM100 transmembrane protein 100 3.07279
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 3.07272
NINJ2 ninjurin 2 3.07218
EZR ezrin 3.06685
PRR5 proline rich 5 (renal) 3.06189
ZBTB10 zinc finger and BTB domain containing 10 3.05729
RNF6 ring finger protein (C3H2C3 type) 6 3.04964
CASP4 caspase 4, apoptosis-related cysteine peptidase 3.0441
ZNHIT6 zinc finger, HIT-type containing 6 3.04368
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 3.03913
NLRP2 NLR family, pyrin domain containing 2 3.03906
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 3.039
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa 3.03878
FOXO1 forkhead box O1 3.03333
C1R complement component 1, r subcomponent 3.03228
RIPK2 receptor-interacting serine-threonine kinase 2 3.02902
RETREG1 reticulophagy regulator 1 3.02785
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 3.0236
GPN2 GPN-loop GTPase 2 3.02333
DNAL4 dynein, axonemal, light chain 4 3.02038
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 3.01901
LYRM9 LYR motif containing 9 3.01265
PAX3 paired box 3 3.01031
SNHG32 small nucleolar RNA host gene 32 3.0099
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 3.0075
H1-2 H1.2 linker histone, cluster member 3.00469
ATP10A ATPase, class V, type 10A 3.0025

decreased expression

Symbol Name Standardized Value
SIRT3 sirtuin 3 -9.19507
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) -8.51896
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 -7.55526
CD40 CD40 molecule, TNF receptor superfamily member 5 -7.42138
CEP57 centrosomal protein 57kDa -7.25826
PPARG peroxisome proliferator-activated receptor gamma -6.94651
CCNB2 cyclin B2 -6.90858
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -6.51648
ZNF804A zinc finger protein 804A -5.91969
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 -5.89085
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -5.87047
DCX doublecortin -5.46162
DEFA5 defensin, alpha 5, Paneth cell-specific -5.30448
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -5.25433
TBP TATA box binding protein -5.21153
AGPS alkylglycerone phosphate synthase -5.18749
CHIC2 cysteine-rich hydrophobic domain 2 -5.0876
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -5.02608
ZNF250 zinc finger protein 250 -5.02301
TMEM11 transmembrane protein 11 -4.99646
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -4.99058
LHFPL2 lipoma HMGIC fusion partner-like 2 -4.92432
QPCTL glutaminyl-peptide cyclotransferase-like -4.90304
RAB5B RAB5B, member RAS oncogene family -4.85216
GOLGA1 golgin A1 -4.7825
CLEC5A C-type lectin domain family 5, member A -4.71206
EOLA1 endothelium and lymphocyte associated ASCH domain 1 -4.65242
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -4.65217
PCP4 Purkinje cell protein 4 -4.63428
ZNF556 zinc finger protein 556 -4.63127
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha -4.62415
DEPDC1B DEP domain containing 1B -4.61183
KDM3A lysine (K)-specific demethylase 3A -4.59249
FPR3 formyl peptide receptor 3 -4.56265
DAD1 defender against cell death 1 -4.53884
SCRN3 secernin 3 -4.50544
NCF2 neutrophil cytosolic factor 2 -4.4999
FOXRED2 FAD-dependent oxidoreductase domain containing 2 -4.48589
CTSC cathepsin C -4.4667
EGF epidermal growth factor -4.46551
ARSF arylsulfatase F -4.44915
ADAM20 ADAM metallopeptidase domain 20 -4.41969
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit -4.40417
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae) -4.39775
NOL4 nucleolar protein 4 -4.37909
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -4.37689
CLTA clathrin, light chain A -4.35084
TBXA2R thromboxane A2 receptor -4.34417
EPHB2 EPH receptor B2 -4.32572
CD320 CD320 molecule -4.30686
NGDN neuroguidin, EIF4E binding protein -4.28023
CCL11 chemokine (C-C motif) ligand 11 -4.26562
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 -4.26513
TCEAL1 transcription elongation factor A (SII)-like 1 -4.20249
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 -4.1848
HK2 hexokinase 2 -4.18349
ODF1 outer dense fiber of sperm tails 1 -4.16452
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -4.13975
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) -4.12619
SCGB1D2 secretoglobin, family 1D, member 2 -4.09198
ZSCAN9 zinc finger and SCAN domain containing 9 -4.07544
PDE7B phosphodiesterase 7B -4.07274
GLE1 GLE1 RNA export mediator -4.06788
PROX1 prospero homeobox 1 -4.05675
RGS6 regulator of G-protein signaling 6 -4.04874
RORB RAR-related orphan receptor B -4.03068
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma -4.03068
ARF4 ADP-ribosylation factor 4 -4.03048
TSHZ2 teashirt zinc finger homeobox 2 -4.02301
MNDA myeloid cell nuclear differentiation antigen -4.00075
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -3.98542
UBFD1 ubiquitin family domain containing 1 -3.98506
SLF2 SMC5-SMC6 complex localization factor 2 -3.97883
BACE2 beta-site APP-cleaving enzyme 2 -3.95164
BFSP2 beaded filament structural protein 2, phakinin -3.94125
TFF3 trefoil factor 3 (intestinal) -3.94076
ATG10 autophagy related 10 -3.93623
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide -3.93469
WDHD1 WD repeat and HMG-box DNA binding protein 1 -3.92935
C11ORF68 chromosome 11 open reading frame 68 -3.92854
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) -3.9163
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 -3.91593
NR1H3 nuclear receptor subfamily 1, group H, member 3 -3.90755
TMLHE trimethyllysine hydroxylase, epsilon -3.90103
AQP9 aquaporin 9 -3.89461
HOXD10 homeobox D10 -3.88697
CSRNP3 cysteine-serine-rich nuclear protein 3 -3.88603
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 -3.8855
PPP1R9A protein phosphatase 1, regulatory subunit 9A -3.88339
TMEM45A transmembrane protein 45A -3.87814
TMEM187 transmembrane protein 187 -3.86127
TFF1 trefoil factor 1 -3.85497
LDAH lipid droplet associated hydrolase -3.85275
PRSS53 protease, serine, 53 -3.85124
MAMLD1 mastermind-like domain containing 1 -3.83598
SDAD1 SDA1 domain containing 1 -3.8339
PIGC phosphatidylinositol glycan anchor biosynthesis, class C -3.83348
STRA6 stimulated by retinoic acid 6 -3.83341
FGF23 fibroblast growth factor 23 -3.81649
RELN reelin -3.81234
AKAP5 A kinase (PRKA) anchor protein 5 -3.81162
CALR calreticulin -3.79752
EMD emerin -3.79064
LYZL6 lysozyme-like 6 -3.76934
AOPEP aminopeptidase O (putative) -3.75925
OTULINL OTU deubiquitinase with linear linkage specificity like -3.75469
CRNKL1 crooked neck pre-mRNA splicing factor 1 -3.74445
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -3.73737
TLR4 toll-like receptor 4 -3.73432
PTPRO protein tyrosine phosphatase, receptor type, O -3.73328
GUCA1A guanylate cyclase activator 1A (retina) -3.73163
ZNF589 zinc finger protein 589 -3.71374
ZNF189 zinc finger protein 189 -3.70465
ACRV1 acrosomal vesicle protein 1 -3.70362
POF1B premature ovarian failure, 1B -3.69098
PRAMEF12 PRAME family member 12 -3.6879
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase -3.68578
RBM4B RNA binding motif protein 4B -3.68375
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 -3.67969
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) -3.66787
SAMD9 sterile alpha motif domain containing 9 -3.66677
RPRM reprimo, TP53 dependent G2 arrest mediator candidate -3.65184
CAPN6 calpain 6 -3.64562
DPEP1 dipeptidase 1 (renal) -3.63926
CKS2 CDC28 protein kinase regulatory subunit 2 -3.63924
MAX MYC associated factor X -3.63843
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -3.63702
PDE10A phosphodiesterase 10A -3.63467
FFAR2 free fatty acid receptor 2 -3.63081
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -3.61632
PDE3B phosphodiesterase 3B, cGMP-inhibited -3.6144
NOX1 NADPH oxidase 1 -3.6069
CLN3 ceroid-lipofuscinosis, neuronal 3 -3.59256
IRF9 interferon regulatory factor 9 -3.58007
CCL24 chemokine (C-C motif) ligand 24 -3.56872
CST7 cystatin F (leukocystatin) -3.56845
GCA grancalcin, EF-hand calcium binding protein -3.56461
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -3.55537
SPINK4 serine peptidase inhibitor, Kazal type 4 -3.55446
FERMT1 fermitin family member 1 -3.54511
ASPHD1 aspartate beta-hydroxylase domain containing 1 -3.54267
CCRL2 chemokine (C-C motif) receptor-like 2 -3.54052
ITGB1BP1 integrin beta 1 binding protein 1 -3.53922
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -3.53206
TXNL1 thioredoxin-like 1 -3.52859
PDIA2 protein disulfide isomerase family A, member 2 -3.52151
PLEK pleckstrin -3.517
CDK5 cyclin-dependent kinase 5 -3.51142
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit -3.50033
MAP2K6 mitogen-activated protein kinase kinase 6 -3.49657
PLCB4 phospholipase C, beta 4 -3.49493
STYXL1 serine/threonine/tyrosine interacting-like 1 -3.49167
EOLA2-DT EOLA2 divergent transcript -3.49134
KLK12 kallikrein-related peptidase 12 -3.48516
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1 -3.4841
TMEM186 transmembrane protein 186 -3.47404
IGBP1 immunoglobulin (CD79A) binding protein 1 -3.46693
KIF11 kinesin family member 11 -3.46447
TACR2 tachykinin receptor 2 -3.463
RNF167 ring finger protein 167 -3.45862
SCGB2A2 secretoglobin, family 2A, member 2 -3.457
CASP2 caspase 2, apoptosis-related cysteine peptidase -3.45591
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 -3.45179
DDX25 DEAD (Asp-Glu-Ala-Asp) box helicase 25 -3.44853
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) -3.44626
ECEL1 endothelin converting enzyme-like 1 -3.44504
TRIM32 tripartite motif containing 32 -3.44396
PCCA propionyl CoA carboxylase, alpha polypeptide -3.43051
POT1 protection of telomeres 1 -3.43037
MECP2 methyl CpG binding protein 2 -3.4291
PTH2R parathyroid hormone 2 receptor -3.42859
TRAF5 TNF receptor-associated factor 5 -3.42629
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -3.42065
ADRA2C adrenoceptor alpha 2C -3.41383
MTARC1 mitochondrial amidoxime reducing component 1 -3.39231
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa -3.38778
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 -3.38499
PAN2 PAN2 poly(A) specific ribonuclease subunit -3.38421
GK3 glycerol kinase 3 -3.38376
ATP2A3 ATPase, Ca++ transporting, ubiquitous -3.38343
C1ORF105 chromosome 1 open reading frame 105 -3.37776
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1 -3.37334
CEP152 centrosomal protein 152kDa -3.37281
METTL25B methyltransferase like 25B -3.36005
IL18BP interleukin 18 binding protein -3.35914
RPA4 replication protein A4, 30kDa -3.35806
CLCN1 chloride channel, voltage-sensitive 1 -3.35361
CAPN9 calpain 9 -3.34365
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator -3.34221
CD209 CD209 molecule -3.33986
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 -3.33933
EIF3F eukaryotic translation initiation factor 3, subunit F -3.33828
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) -3.33727
UBE2I ubiquitin-conjugating enzyme E2I -3.33337
NVL nuclear VCP-like -3.32965
RAB26 RAB26, member RAS oncogene family -3.32296
GPNMB glycoprotein (transmembrane) nmb -3.32267
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 -3.31815
MRPS30 mitochondrial ribosomal protein S30 -3.3133
ODAM odontogenic, ameloblast asssociated -3.30681
PRLR prolactin receptor -3.30445
ANKZF1 ankyrin repeat and zinc finger domain containing 1 -3.30244
CCL8 chemokine (C-C motif) ligand 8 -3.2995
INPP5J inositol polyphosphate-5-phosphatase J -3.29397
PDE2A phosphodiesterase 2A, cGMP-stimulated -3.29366
OASL 2'-5'-oligoadenylate synthetase-like -3.28988
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6 -3.2881
PDE3A phosphodiesterase 3A, cGMP-inhibited -3.28622
AP1S1 adaptor-related protein complex 1, sigma 1 subunit -3.28026
ZFP2 ZFP2 zinc finger protein -3.27952
OLAH oleoyl-ACP hydrolase -3.27887
ZCCHC4 zinc finger, CCHC domain containing 4 -3.2774
PLCL2 phospholipase C-like 2 -3.27579
PRSS3 protease, serine, 3 -3.27494
EOLA2 endothelium and lymphocyte associated ASCH domain 2 -3.27278
TMPRSS11D transmembrane protease, serine 11D -3.27228
UGT8 UDP glycosyltransferase 8 -3.26168
CCR3 chemokine (C-C motif) receptor 3 -3.25462
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -3.25073
EPB41L4A erythrocyte membrane protein band 4.1 like 4A -3.2493
ANXA13 annexin A13 -3.24514
WASF1 WAS protein family, member 1 -3.24466
ANKRD17 ankyrin repeat domain 17 -3.24176
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -3.24
BAG5 BCL2-associated athanogene 5 -3.23372
INTS7 integrator complex subunit 7 -3.22723
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 -3.22702
TAGLN3 transgelin 3 -3.22539
MYL5 myosin, light chain 5, regulatory -3.22426
SPINK1 serine peptidase inhibitor, Kazal type 1 -3.2241
CTSE cathepsin E -3.21967
TXLNG taxilin gamma -3.21788
HOXD3 homeobox D3 -3.20438
SDHAF1 succinate dehydrogenase complex assembly factor 1 -3.1932
FLNA filamin A, alpha -3.19145
PEX1 peroxisomal biogenesis factor 1 -3.19036
TMEM106C transmembrane protein 106C -3.19028
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 -3.18672
APMAP adipocyte plasma membrane associated protein -3.1839
KCMF1 potassium channel modulatory factor 1 -3.18175
IFITM1 interferon induced transmembrane protein 1 -3.17948
COPS7B COP9 signalosome subunit 7B -3.17563
OGG1 8-oxoguanine DNA glycosylase -3.17299
CCDC88C coiled-coil domain containing 88C -3.17162
OXA1L oxidase (cytochrome c) assembly 1-like -3.16817
NR5A2 nuclear receptor subfamily 5, group A, member 2 -3.16726
SLAMF8 SLAM family member 8 -3.16356
MED6 mediator complex subunit 6 -3.16344
NSDHL NAD(P) dependent steroid dehydrogenase-like -3.15962
EIF5 eukaryotic translation initiation factor 5 -3.15961
LDOC1 leucine zipper, down-regulated in cancer 1 -3.15629
GLUL glutamate-ammonia ligase -3.15597
CRHR2 corticotropin releasing hormone receptor 2 -3.15283
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 -3.15048
ACSL5 acyl-CoA synthetase long-chain family member 5 -3.14214
EIF3H eukaryotic translation initiation factor 3, subunit H -3.13914
ERCC4 excision repair cross-complementation group 4 -3.136
ACIN1 apoptotic chromatin condensation inducer 1 -3.13556
RNF186 ring finger protein 186 -3.13548
ELANE elastase, neutrophil expressed -3.12839
FSHR follicle stimulating hormone receptor -3.12814
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 -3.12188
ACSBG2 acyl-CoA synthetase bubblegum family member 2 -3.11931
SSR2 signal sequence receptor, beta (translocon-associated protein beta) -3.11854
RIGI RNA sensor RIG-I -3.11402
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -3.11202
MMP12 matrix metallopeptidase 12 -3.11166
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) -3.10841
KDM4B lysine (K)-specific demethylase 4B -3.1063
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -3.10465
SH3BP1 SH3-domain binding protein 1 -3.10219
TSPAN9 tetraspanin 9 -3.10145
UBQLN3 ubiquilin 3 -3.10091
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 -3.09709
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -3.09563
FSTL4 follistatin-like 4 -3.09269
RAP2C RAP2C, member of RAS oncogene family -3.09238
CNTN6 contactin 6 -3.08859
TRIM21 tripartite motif containing 21 -3.08202
PDK1 pyruvate dehydrogenase kinase, isozyme 1 -3.08063
CEP68 centrosomal protein 68kDa -3.07948
RTRAF RNA transcription, translation and transport factor -3.07518
KCTD7 potassium channel tetramerization domain containing 7 -3.07469
CXCL11 chemokine (C-X-C motif) ligand 11 -3.07461
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -3.07398
MARCHF7 membrane associated ring-CH-type finger 7 -3.07346
GGTLC2 gamma-glutamyltransferase light chain 2 -3.06847
CLEC1B C-type lectin domain family 1, member B -3.06828
UNC13B unc-13 homolog B (C. elegans) -3.06825
ATP10B ATPase, class V, type 10B -3.06247
RABAC1 Rab acceptor 1 (prenylated) -3.05813
REG3A regenerating islet-derived 3 alpha -3.05771
CRCT1 cysteine-rich C-terminal 1 -3.05727
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -3.05335
CRISP1 cysteine-rich secretory protein 1 -3.05329
NRBP1 nuclear receptor binding protein 1 -3.05291
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -3.05174
ADCY8 adenylate cyclase 8 (brain) -3.05108
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 -3.04892
TDP1 tyrosyl-DNA phosphodiesterase 1 -3.04659
STK10 serine/threonine kinase 10 -3.04559
CLC Charcot-Leyden crystal galectin -3.03978
ADCY6 adenylate cyclase 6 -3.03731
CRH corticotropin releasing hormone -3.03635
ANO3 anoctamin 3 -3.03554
REXO5 RNA exonuclease 5 -3.0331
ZFAND6 zinc finger, AN1-type domain 6 -3.0303
IST1 increased sodium tolerance 1 homolog (yeast) -3.02703
TRAPPC14 trafficking protein particle complex subunit 14 -3.02544
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -3.02358
NCF4 neutrophil cytosolic factor 4, 40kDa -3.02314
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -3.02176
PSCA prostate stem cell antigen -3.02015
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -3.01727
DDO D-aspartate oxidase -3.01591
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 -3.01456
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 -3.01252
NUSAP1 nucleolar and spindle associated protein 1 -3.00895
POPDC2 popeye domain containing 2 -3.0013
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma -3.00105