| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the levodopa-1472 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY7 | adenylate cyclase 7 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| APC | adenomatous polyposis coli |
| AQP1 | aquaporin 1 (Colton blood group) |
| ATG13 | autophagy related 13 |
| BMP15 | bone morphogenetic protein 15 |
| BMP5 | bone morphogenetic protein 5 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CAPN15 | calpain 15 |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CD58 | CD58 molecule |
| CD8A | CD8a molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLMN | calmin (calponin-like, transmembrane) |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CTNS | cystinosin, lysosomal cystine transporter |
| CUL7 | cullin 7 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DFNB31 | deafness, autosomal recessive 31 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EMID1 | EMI domain containing 1 |
| ESR1 | estrogen receptor 1 |
| FADS3 | fatty acid desaturase 3 |
| FAM134B | family with sequence similarity 134, member B |
| FAM184A | family with sequence similarity 184, member A |
| FAM212B | family with sequence similarity 212, member B |
| FAM46C | family with sequence similarity 46, member C |
| FBXO11 | F-box protein 11 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FNBP1 | formin binding protein 1 |
| FOXG1 | forkhead box G1 |
| GPR137 | G protein-coupled receptor 137 |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| HDAC5 | histone deacetylase 5 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HOXC10 | homeobox C10 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IDS | iduronate 2-sulfatase |
| IGL | immunoglobulin lambda locus |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| IQCE | IQ motif containing E |
| IRS2 | insulin receptor substrate 2 |
| JMJD4 | jumonji domain containing 4 |
| KDM4C | lysine (K)-specific demethylase 4C |
| KLK1 | kallikrein 1 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MED6 | mediator complex subunit 6 |
| MID1 | midline 1 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MMP11 | matrix metallopeptidase 11 |
| MTMR1 | myotubularin related protein 1 |
| NCAN | neurocan |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRSN2 | neurensin 2 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OTUD4 | OTU deubiquitinase 4 |
| OVOL2 | ovo-like zinc finger 2 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PEX16 | peroxisomal biogenesis factor 16 |
| PGAP3 | post-GPI attachment to proteins 3 |
| PITX1 | paired-like homeodomain 1 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| RPS28 | ribosomal protein S28 |
| RUNX1 | runt-related transcription factor 1 |
| SAFB | scaffold attachment factor B |
| SIN3B | SIN3 transcription regulator family member B |
| SIRT5 | sirtuin 5 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SRRT | serrate, RNA effector molecule |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TGM2 | transglutaminase 2 |
| THBS3 | thrombospondin 3 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMEM242 | transmembrane protein 242 |
| TRBC1 | T cell receptor beta constant 1 |
| TRIM2 | tripartite motif containing 2 |
| VN1R1 | vomeronasal 1 receptor 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| YY2 | YY2 transcription factor |
| ZNF318 | zinc finger protein 318 |
| ZNF362 | zinc finger protein 362 |
| Symbol | Name |
|---|---|
| AARSD1 | alanyl-tRNA synthetase domain containing 1 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| AMPD2 | adenosine monophosphate deaminase 2 |
| ANKRD36 | ankyrin repeat domain 36 |
| ARMC6 | armadillo repeat containing 6 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCDC15 | coiled-coil domain containing 15 |
| CCDC9 | coiled-coil domain containing 9 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEP97 | centrosomal protein 97kDa |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CTAGE9 | CTAGE family, member 9 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DUSP2 | dual specificity phosphatase 2 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EPHA2 | EPH receptor A2 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| FA2H | fatty acid 2-hydroxylase |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| HDAC4 | histone deacetylase 4 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2BF | histone cluster 1, H2bf |
| HSPA2 | heat shock 70kDa protein 2 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL22 | interleukin 22 |
| IRF1 | interferon regulatory factor 1 |
| IRF6 | interferon regulatory factor 6 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| JUNB | jun B proto-oncogene |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC390998 | ribosomal protein L10 pseudogene |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MANBA | mannosidase, beta A, lysosomal |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MCC | mutated in colorectal cancers |
| MEFV | Mediterranean fever |
| MT1H | metallothionein 1H |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NKX3-2 | NK3 homeobox 2 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRR14L | proline rich 14-like |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RIN2 | Ras and Rab interactor 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF43 | ring finger protein 43 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCAMP5 | secretory carrier membrane protein 5 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SP1 | Sp1 transcription factor |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| USP36 | ubiquitin specific peptidase 36 |
| XAB2 | XPA binding protein 2 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF219 | zinc finger protein 219 |
| ZNF254 | zinc finger protein 254 |
| ZNF350 | zinc finger protein 350 |
| ZNF770 | zinc finger protein 770 |
| ZNF816 | zinc finger protein 816 |
