levodopa-4571 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the levodopa-4571 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ACAN aggrecan
AKR1C4 aldo-keto reductase family 1, member C4
ALDOB aldolase B, fructose-bisphosphate
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASPH aspartate beta-hydroxylase
C8A complement component 8, alpha polypeptide
CALML3 calmodulin-like 3
CD68 CD68 molecule
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CDH10 cadherin 10, type 2 (T2-cadherin)
CEP295 centrosomal protein 295kDa
CLEC4A C-type lectin domain family 4, member A
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COL2A1 collagen, type II, alpha 1
COL7A1 collagen, type VII, alpha 1
CREM cAMP responsive element modulator
CRHR2 corticotropin releasing hormone receptor 2
CSHL1 chorionic somatomammotropin hormone-like 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DPF1 D4, zinc and double PHD fingers family 1
EFCAB11 EF-hand calcium binding domain 11
ESRRG estrogen-related receptor gamma
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM110B family with sequence similarity 110, member B
FAM174B family with sequence similarity 174, member B
FAM63B family with sequence similarity 63, member B
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLJ11710 uncharacterized protein FLJ11710
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAL galanin/GMAP prepropeptide
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GGT1 gamma-glutamyltransferase 1
GLP1R glucagon-like peptide 1 receptor
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPC3 glypican 3
GPR27 G protein-coupled receptor 27
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HOXB6 homeobox B6
INSR insulin receptor
KDR kinase insert domain receptor
KIAA0485 uncharacterized LOC57235
KLHL22 kelch-like family member 22
KLK7 kallikrein-related peptidase 7
KRIT1 KRIT1, ankyrin repeat containing
LATS1 large tumor suppressor kinase 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC399491
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP2K7 mitogen-activated protein kinase kinase 7
MFAP3L microfibrillar-associated protein 3-like
MTSS1L metastasis suppressor 1-like
NCR2 natural cytotoxicity triggering receptor 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NUP54 nucleoporin 54kDa
PALM paralemmin
PAOX polyamine oxidase (exo-N4-amino)
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDCD2 programmed cell death 2
PDE4DIP phosphodiesterase 4D interacting protein
PGPEP1 pyroglutamyl-peptidase I
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLD1 phospholipase D1, phosphatidylcholine-specific
PODNL1 podocan-like 1
PRDM14 PR domain containing 14
PRSS22 protease, serine, 22
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTN pleiotrophin
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAP1GAP RAP1 GTPase activating protein
RYR2 ryanodine receptor 2 (cardiac)
S100A11 S100 calcium binding protein A11
SERHL2 serine hydrolase-like 2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMG6 SMG6 nonsense mediated mRNA decay factor
SOGA1 suppressor of glucose, autophagy associated 1
SPTB spectrin, beta, erythrocytic
ST18 suppression of tumorigenicity 18, zinc finger
STK3 serine/threonine kinase 3
SVIL supervillin
TENM1 teneurin transmembrane protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLE2 transducin-like enhancer of split 2
TMOD1 tropomodulin 1
TMPRSS4 transmembrane protease, serine 4
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOX thymocyte selection-associated high mobility group box
TP73-AS1 TP73 antisense RNA 1
TRIL TLR4 interactor with leucine-rich repeats
TUBB2B tubulin, beta 2B class IIb
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
ZBTB20 zinc finger and BTB domain containing 20
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF24 zinc finger protein 24
ZNF280B zinc finger protein 280B
ZNF286A zinc finger protein 286A
ZNF384 zinc finger protein 384
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABHD17B abhydrolase domain containing 17B
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ACYP2 acylphosphatase 2, muscle type
ADAM15 ADAM metallopeptidase domain 15
AGO4 argonaute RISC catalytic component 4
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALS2CL ALS2 C-terminal like
ANKFY1 ankyrin repeat and FYVE domain containing 1
AOC2 amine oxidase, copper containing 2 (retina-specific)
ASB7 ankyrin repeat and SOCS box containing 7
BAK1 BCL2-antagonist/killer 1
BNC2 basonuclin 2
C1ORF56 chromosome 1 open reading frame 56
C5ORF30 chromosome 5 open reading frame 30
CA5B carbonic anhydrase VB, mitochondrial
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC85C coiled-coil domain containing 85C
CES3 carboxylesterase 3
CFAP69 cilia and flagella associated protein 69
CHM choroideremia (Rab escort protein 1)
COL9A2 collagen, type IX, alpha 2
CYBRD1 cytochrome b reductase 1
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EXOC5 exocyst complex component 5
FAM186A family with sequence similarity 186, member A
FCMR Fc fragment of IgM receptor
FKBP10 FK506 binding protein 10, 65 kDa
GDAP1 ganglioside induced differentiation associated protein 1
GDAP2 ganglioside induced differentiation associated protein 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR176 G protein-coupled receptor 176
HIST1H2BM histone cluster 1, H2bm
HIST1H4A histone cluster 1, H4a
HIST2H2AA3 histone cluster 2, H2aa3
HOXA1 homeobox A1
HOXC13 homeobox C13
IL11RA interleukin 11 receptor, alpha
IMPAD1 inositol monophosphatase domain containing 1
INCENP inner centromere protein antigens 135/155kDa
KCTD20 potassium channel tetramerization domain containing 20
KIAA1107 KIAA1107
KLHL12 kelch-like family member 12
KLHL36 kelch-like family member 36
LIG4 ligase IV, DNA, ATP-dependent
LOC257152 uncharacterized LOC257152
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6D lymphocyte antigen 6 complex, locus D
LYRM9 LYR motif containing 9
MAGEA3 melanoma antigen family A3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MT1M metallothionein 1M
MYO1F myosin IF
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OVGP1 oviductal glycoprotein 1, 120kDa
PDLIM2 PDZ and LIM domain 2 (mystique)
PECR peroxisomal trans-2-enoyl-CoA reductase
PEX26 peroxisomal biogenesis factor 26
PPCS phosphopantothenoylcysteine synthetase
PPT2 palmitoyl-protein thioesterase 2
PROX1 prospero homeobox 1
PSAT1 phosphoserine aminotransferase 1
PSENEN presenilin enhancer gamma secretase subunit
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB23 RAB23, member RAS oncogene family
RAB36 RAB36, member RAS oncogene family
RCL1 RNA terminal phosphate cyclase-like 1
SAYSD1 SAYSVFN motif domain containing 1
SEC24B SEC24 family member B
SEPP1 selenoprotein P, plasma, 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3GL2 SH3-domain GRB2-like 2
SLC25A40 solute carrier family 25, member 40
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
STK16 serine/threonine kinase 16
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYNGR3 synaptogyrin 3
SYT17 synaptotagmin XVII
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TIGAR TP53 induced glycolysis regulatory phosphatase
TMEM230 transmembrane protein 230
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM25 tripartite motif containing 25
TSPAN1 tetraspanin 1
TUBA3C tubulin, alpha 3c
YIPF5 Yip1 domain family, member 5
ZNF334 zinc finger protein 334
ZNF343 zinc finger protein 343
ZNF37BP zinc finger protein 37B, pseudogene
ZNF571 zinc finger protein 571