levomepromazine-3440 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the levomepromazine-3440 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ADAP1 ArfGAP with dual PH domains 1
ADGRL1 adhesion G protein-coupled receptor L1
ANP32A-IT1 ANP32A intronic transcript 1
APOM apolipoprotein M
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ATP10A ATPase, class V, type 10A
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BBS9 Bardet-Biedl syndrome 9
BHLHE40 basic helix-loop-helix family, member e40
BMP7 bone morphogenetic protein 7
BST2 bone marrow stromal cell antigen 2
C1QTNF3 C1q and tumor necrosis factor related protein 3
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CAPN15 calpain 15
CCDC132 coiled-coil domain containing 132
CCNG2 cyclin G2
CFDP1 craniofacial development protein 1
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DPY19L1P1 DPY19L1 pseudogene 1
EPOR erythropoietin receptor
FGL1 fibrinogen-like 1
FH fumarate hydratase
FKBP8 FK506 binding protein 8, 38kDa
FOXN3 forkhead box N3
FPGT fucose-1-phosphate guanylyltransferase
GLRX3 glutaredoxin 3
GPR143 G protein-coupled receptor 143
HIST1H1E histone cluster 1, H1e
HIST1H4A histone cluster 1, H4a
HLA-G major histocompatibility complex, class I, G
HPS1 Hermansky-Pudlak syndrome 1
ICAM1 intercellular adhesion molecule 1
IL11 interleukin 11
INCENP inner centromere protein antigens 135/155kDa
INSIG1 insulin induced gene 1
IRF1 interferon regulatory factor 1
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
ITGB4 integrin, beta 4
ITPK1 inositol-tetrakisphosphate 1-kinase
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KIDINS220 kinase D-interacting substrate, 220kDa
KLHL24 kelch-like family member 24
LUZP1 leucine zipper protein 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBTD1 mbt domain containing 1
MED28 mediator complex subunit 28
MTRF1L mitochondrial translational release factor 1-like
MXD3 MAX dimerization protein 3
NEURL1 neuralized E3 ubiquitin protein ligase 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NR4A2 nuclear receptor subfamily 4, group A, member 2
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PGAP1 post-GPI attachment to proteins 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCD1 phospholipase C, delta 1
POPDC3 popeye domain containing 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PTGES prostaglandin E synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
QPCTL glutaminyl-peptide cyclotransferase-like
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100A11 S100 calcium binding protein A11
S100A4 S100 calcium binding protein A4
SAPCD1 suppressor APC domain containing 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SIAH1 siah E3 ubiquitin protein ligase 1
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC35E2 solute carrier family 35, member E2
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNAI2 snail family zinc finger 2
SOCS1 suppressor of cytokine signaling 1
SREBF2 sterol regulatory element binding transcription factor 2
SSH3 slingshot protein phosphatase 3
STYK1 serine/threonine/tyrosine kinase 1
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TBC1D17 TBC1 domain family, member 17
TET3 tet methylcytosine dioxygenase 3
TGM2 transglutaminase 2
TMCO1 transmembrane and coiled-coil domains 1
TMPRSS15 transmembrane protease, serine 15
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TSTA3 tissue specific transplantation antigen P35B
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
USP34 ubiquitin specific peptidase 34
WDR62 WD repeat domain 62
ZBTB48 zinc finger and BTB domain containing 48
ZCCHC11 zinc finger, CCHC domain containing 11
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF24 zinc finger protein 24

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACTL8 actin-like 8
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATAD3A ATPase family, AAA domain containing 3A
ATF7IP2 activating transcription factor 7 interacting protein 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAHCC1 BAH domain and coiled-coil containing 1
BFSP1 beaded filament structural protein 1, filensin
C17ORF80 chromosome 17 open reading frame 80
C2ORF44 chromosome 2 open reading frame 44
C5ORF45 chromosome 5 open reading frame 45
CAMTA2 calmodulin binding transcription activator 2
CCDC25 coiled-coil domain containing 25
CCDC69 coiled-coil domain containing 69
CCDC9 coiled-coil domain containing 9
CCNE1 cyclin E1
CCNL2 cyclin L2
CCP110 centriolar coiled coil protein 110kDa
CDK20 cyclin-dependent kinase 20
CENPT centromere protein T
CLUH clustered mitochondria (cluA/CLU1) homolog
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNN2 calponin 2
CST6 cystatin E/M
CXORF56 chromosome X open reading frame 56
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGAT1 diacylglycerol O-acyltransferase 1
DGKE diacylglycerol kinase, epsilon 64kDa
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DUSP13 dual specificity phosphatase 13
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EXO5 exonuclease 5
FAM131A family with sequence similarity 131, member A
FAM155B family with sequence similarity 155, member B
FBXO46 F-box protein 46
FBXW12 F-box and WD repeat domain containing 12
FMO4 flavin containing monooxygenase 4
FSTL3 follistatin-like 3 (secreted glycoprotein)
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GDAP1 ganglioside induced differentiation associated protein 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GUSBP3 glucuronidase, beta pseudogene 3
H2AFY2 H2A histone family, member Y2
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
IFI35 interferon-induced protein 35
IGFBP6 insulin-like growth factor binding protein 6
IL4R interleukin 4 receptor
INF2 inverted formin, FH2 and WH2 domain containing
IRF6 interferon regulatory factor 6
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
JMJD4 jumonji domain containing 4
KRT13 keratin 13, type I
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MED9 mediator complex subunit 9
MFSD11 major facilitator superfamily domain containing 11
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NPTX1 neuronal pentraxin I
NSD1 nuclear receptor binding SET domain protein 1
PCDHB8 protocadherin beta 8
PGPEP1 pyroglutamyl-peptidase I
PRPH peripherin
PRR15L proline rich 15-like
RANBP17 RAN binding protein 17
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPAP1 RNA polymerase II associated protein 1
RPL13P5 ribosomal protein L13 pseudogene 5
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIRT6 sirtuin 6
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX1A syntaxin 1A (brain)
TEP1 telomerase-associated protein 1
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLN1 talin 1
TRAIP TRAF interacting protein
TSPAN14 tetraspanin 14
TSPYL2 TSPY-like 2
TTC30A tetratricopeptide repeat domain 30A
TUBA3C tubulin, alpha 3c
UBE2L6 ubiquitin-conjugating enzyme E2L 6
USP27X ubiquitin specific peptidase 27, X-linked
VAX2 ventral anterior homeobox 2
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR4 WD repeat domain 4
XYLT2 xylosyltransferase II
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF446 zinc finger protein 446
ZNF652 zinc finger protein 652