levomepromazine-4723 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the levomepromazine-4723 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANGEL2 angel homolog 2 (Drosophila)
ANKH ANKH inorganic pyrophosphate transport regulator
APOE apolipoprotein E
ARTN artemin
BDKRB2 bradykinin receptor B2
BHLHE40 basic helix-loop-helix family, member e40
BMP1 bone morphogenetic protein 1
BTG2 BTG family, member 2
C10ORF95 chromosome 10 open reading frame 95
C11ORF16 chromosome 11 open reading frame 16
C1QL1 complement component 1, q subcomponent-like 1
CCNG2 cyclin G2
CEMIP cell migration inducing protein, hyaluronan binding
CFLAR CASP8 and FADD-like apoptosis regulator
COL5A1 collagen, type V, alpha 1
CREM cAMP responsive element modulator
CRYBB2P1 crystallin, beta B2 pseudogene 1
CSF1 colony stimulating factor 1 (macrophage)
CTBS chitobiase, di-N-acetyl-
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DIXDC1 DIX domain containing 1
DNA2 DNA replication helicase/nuclease 2
DPP4 dipeptidyl-peptidase 4
EFNB3 ephrin-B3
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
FAS Fas cell surface death receptor
FDPS farnesyl diphosphate synthase
FLCN folliculin
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GAS7 growth arrest-specific 7
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GRB10 growth factor receptor-bound protein 10
GULP1 GULP, engulfment adaptor PTB domain containing 1
HIF3A hypoxia inducible factor 3, alpha subunit
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IL1B interleukin 1, beta
IL5RA interleukin 5 receptor, alpha
IMPG1 interphotoreceptor matrix proteoglycan 1
INCENP inner centromere protein antigens 135/155kDa
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KAT5 K(lysine) acetyltransferase 5
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCTD7 potassium channel tetramerization domain containing 7
KDM5A lysine (K)-specific demethylase 5A
KIAA1109 KIAA1109
KLF2 Kruppel-like factor 2
KLHL24 kelch-like family member 24
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LAMA4 laminin, alpha 4
LAMP1 lysosomal-associated membrane protein 1
LGALS8 lectin, galactoside-binding, soluble, 8
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MMP3 matrix metallopeptidase 3
NCKIPSD NCK interacting protein with SH3 domain
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME5 NME/NM23 family member 5
ONECUT2 one cut homeobox 2
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHGB5 protocadherin gamma subfamily B, 5
PCNX pecanex homolog (Drosophila)
PHF20 PHD finger protein 20
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPARG peroxisome proliferator-activated receptor gamma
PRKCH protein kinase C, eta
QKI QKI, KH domain containing, RNA binding
RAB11B RAB11B, member RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RASAL2 RAS protein activator like 2
RDH8 retinol dehydrogenase 8 (all-trans)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPGR retinitis pigmentosa GTPase regulator
RPS3A ribosomal protein S3A
SAP30 Sin3A-associated protein, 30kDa
SCAND2P SCAN domain containing 2 pseudogene
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLPI secretory leukocyte peptidase inhibitor
SOAT1 sterol O-acyltransferase 1
SRD5A3 steroid 5 alpha-reductase 3
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TEX14 testis expressed 14
TMPRSS4 transmembrane protease, serine 4
TRA T cell receptor alpha locus
UBTD1 ubiquitin domain containing 1
UHRF1BP1L UHRF1 binding protein 1-like
VEZT vezatin, adherens junctions transmembrane protein
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
VWA5A von Willebrand factor A domain containing 5A
ZFHX2 zinc finger homeobox 2
ZNF606 zinc finger protein 606
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACBD4 acyl-CoA binding domain containing 4
ADAM23 ADAM metallopeptidase domain 23
AGMAT agmatine ureohydrolase (agmatinase)
ALS2CL ALS2 C-terminal like
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARID3B AT rich interactive domain 3B (BRIGHT-like)
C14ORF79 chromosome 14 open reading frame 79
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CDHR2 cadherin-related family member 2
CDK6 cyclin-dependent kinase 6
CDON cell adhesion associated, oncogene regulated
CENPO centromere protein O
CLCN6 chloride channel, voltage-sensitive 6
CPNE7 copine VII
CPTP ceramide-1-phosphate transfer protein
CSF1R colony stimulating factor 1 receptor
CTIF CBP80/20-dependent translation initiation factor
DNALI1 dynein, axonemal, light intermediate chain 1
DOC2A double C2-like domains, alpha
DUSP8 dual specificity phosphatase 8
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV4 ets variant 4
FAM184A family with sequence similarity 184, member A
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP10 FK506 binding protein 10, 65 kDa
GLI3 GLI family zinc finger 3
GNA14 guanine nucleotide binding protein (G protein), alpha 14
HAMP hepcidin antimicrobial peptide
HDAC4 histone deacetylase 4
HIST1H2AK histone cluster 1, H2ak
HIST1H2BN histone cluster 1, H2bn
HIST1H2BO histone cluster 1, H2bo
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA6 homeobox A6
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL12B interleukin 12B
IL2 interleukin 2
ITGB7 integrin, beta 7
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIF21B kinesin family member 21B
KLHL26 kelch-like family member 26
KRT14 keratin 14, type I
LRP3 low density lipoprotein receptor-related protein 3
MAP1S microtubule-associated protein 1S
MTA2 metastasis associated 1 family, member 2
MYLK myosin light chain kinase
NEUROD1 neuronal differentiation 1
NEUROD4 neuronal differentiation 4
NFE2L3 nuclear factor, erythroid 2-like 3
NLRX1 NLR family member X1
NOL10 nucleolar protein 10
NPR3 natriuretic peptide receptor 3
NUP62CL nucleoporin 62kDa C-terminal like
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAIP2B poly(A) binding protein interacting protein 2B
PARPBP PARP1 binding protein
PDE12 phosphodiesterase 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PGPEP1 pyroglutamyl-peptidase I
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRSS53 protease, serine, 53
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RHOBTB2 Rho-related BTB domain containing 2
RNF121 ring finger protein 121
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPAP1 RNA polymerase II associated protein 1
RUSC2 RUN and SH3 domain containing 2
S100A2 S100 calcium binding protein A2
SAYSD1 SAYSVFN motif domain containing 1
SERGEF secretion regulating guanine nucleotide exchange factor
SNTA1 syntrophin, alpha 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STEAP4 STEAP family member 4
SYNC syncoilin, intermediate filament protein
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TICAM1 toll-like receptor adaptor molecule 1
TMC5 transmembrane channel-like 5
TMEM121 transmembrane protein 121
TMEM8B transmembrane protein 8B
TTLL1 tubulin tyrosine ligase-like family member 1
TUBB2B tubulin, beta 2B class IIb
ZNF480 zinc finger protein 480
ZNF701 zinc finger protein 701
ZNF747 zinc finger protein 747