levopropoxyphene-3543 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the levopropoxyphene-3543 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCK2 aarF domain containing kinase 2
ADGRF5 adhesion G protein-coupled receptor F5
AGFG2 ArfGAP with FG repeats 2
ALCAM activated leukocyte cell adhesion molecule
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALS2CL ALS2 C-terminal like
ANPEP alanyl (membrane) aminopeptidase
ARMC8 armadillo repeat containing 8
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BAAT bile acid CoA:amino acid N-acyltransferase
BHLHE41 basic helix-loop-helix family, member e41
BTD biotinidase
C10ORF12 chromosome 10 open reading frame 12
C14ORF93 chromosome 14 open reading frame 93
CAPN10 calpain 10
CARD9 caspase recruitment domain family, member 9
CCDC64 coiled-coil domain containing 64
CD34 CD34 molecule
CD58 CD58 molecule
CD6 CD6 molecule
CD83 CD83 molecule
CDC14A cell division cycle 14A
CYLD cylindromatosis (turban tumor syndrome)
DACH1 dachshund family transcription factor 1
DBF4B DBF4 zinc finger B
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DMXL2 Dmx-like 2
DOCK4 dedicator of cytokinesis 4
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPF1 D4, zinc and double PHD fingers family 1
FAM184A family with sequence similarity 184, member A
FANCA Fanconi anemia, complementation group A
FGD1 FYVE, RhoGEF and PH domain containing 1
GLDC glycine dehydrogenase (decarboxylating)
GLP1R glucagon-like peptide 1 receptor
GOSR2 golgi SNAP receptor complex member 2
GRK5 G protein-coupled receptor kinase 5
GRM3 glutamate receptor, metabotropic 3
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HEG1 heart development protein with EGF-like domains 1
HIC2 hypermethylated in cancer 2
HIST1H3F histone cluster 1, H3f
IFT27 intraflagellar transport 27
IGSF6 immunoglobulin superfamily, member 6
IL11 interleukin 11
IL1B interleukin 1, beta
IL6R interleukin 6 receptor
INHBE inhibin, beta E
KIAA1107 KIAA1107
KRAS Kirsten rat sarcoma viral oncogene homolog
MAK male germ cell-associated kinase
MALL mal, T-cell differentiation protein-like
MALT1 MALT1 paracaspase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MRPL41 mitochondrial ribosomal protein L41
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NFX1 nuclear transcription factor, X-box binding 1
NIPAL2 NIPA-like domain containing 2
NMT2 N-myristoyltransferase 2
NPR2 natriuretic peptide receptor 2
NPR3 natriuretic peptide receptor 3
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
OSGIN1 oxidative stress induced growth inhibitor 1
PHF1 PHD finger protein 1
PIDD1 p53-induced death domain protein 1
PLAGL1 pleiomorphic adenoma gene-like 1
PP14571 uncharacterized LOC100130449
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PTPRS protein tyrosine phosphatase, receptor type, S
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RB1 retinoblastoma 1
RPL10 ribosomal protein L10
RPL23AP32 ribosomal protein L23a pseudogene 32
RPL7 ribosomal protein L7
RPS3A ribosomal protein S3A
S100A11 S100 calcium binding protein A11
SAFB2 scaffold attachment factor B2
SHARPIN SHANK-associated RH domain interactor
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLIT2 slit homolog 2 (Drosophila)
SOAT1 sterol O-acyltransferase 1
STC1 stanniocalcin 1
SYBU syntabulin (syntaxin-interacting)
SYT11 synaptotagmin XI
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB2 transforming growth factor, beta 2
TLK1 tousled-like kinase 1
TRD T cell receptor delta locus
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSHR thyroid stimulating hormone receptor
UHRF1BP1L UHRF1 binding protein 1-like
VIPR1 vasoactive intestinal peptide receptor 1
WDR1 WD repeat domain 1
WNT2B wingless-type MMTV integration site family, member 2B
ZER1 zyg-11 related, cell cycle regulator
ZNF510 zinc finger protein 510
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADGRG2 adhesion G protein-coupled receptor G2
ADTRP androgen-dependent TFPI-regulating protein
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AMT aminomethyltransferase
AP1B1 adaptor-related protein complex 1, beta 1 subunit
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARC activity-regulated cytoskeleton-associated protein
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BAHD1 bromo adjacent homology domain containing 1
BBC3 BCL2 binding component 3
BCORL1 BCL6 corepressor-like 1
C11ORF16 chromosome 11 open reading frame 16
C19ORF40 chromosome 19 open reading frame 40
C22ORF46 chromosome 22 open reading frame 46
C8ORF60 chromosome 8 open reading frame 60
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC121 coiled-coil domain containing 121
CCDC186 coiled-coil domain containing 186
CEP170B centrosomal protein 170B
CLCA1 chloride channel accessory 1
CNTFR ciliary neurotrophic factor receptor
CPSF3L cleavage and polyadenylation specific factor 3-like
CRELD1 cysteine-rich with EGF-like domains 1
CTSF cathepsin F
CUZD1 CUB and zona pellucida-like domains 1
CXCR2 chemokine (C-X-C motif) receptor 2
DAGLA diacylglycerol lipase, alpha
DPY19L1P1 DPY19L1 pseudogene 1
ELP6 elongator acetyltransferase complex subunit 6
EMID1 EMI domain containing 1
FABP6 fatty acid binding protein 6, ileal
FANCE Fanconi anemia, complementation group E
FER fer (fps/fes related) tyrosine kinase
FLJ11710 uncharacterized protein FLJ11710
FLNC filamin C, gamma
FRMD1 FERM domain containing 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLCE glucuronic acid epimerase
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPR27 G protein-coupled receptor 27
GRIP2 glutamate receptor interacting protein 2
GTPBP2 GTP binding protein 2
HELZ helicase with zinc finger
HIST1H2AK histone cluster 1, H2ak
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KDM5C lysine (K)-specific demethylase 5C
KIF13A kinesin family member 13A
KRT24 keratin 24, type I
LAMB3 laminin, beta 3
LAX1 lymphocyte transmembrane adaptor 1
LIME1 Lck interacting transmembrane adaptor 1
MRPS18C mitochondrial ribosomal protein S18C
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MXD3 MAX dimerization protein 3
MYO1F myosin IF
NCALD neurocalcin delta
NKX3-2 NK3 homeobox 2
NNAT neuronatin
NT5DC3 5'-nucleotidase domain containing 3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSMR oncostatin M receptor
PALM paralemmin
PCBP4 poly(rC) binding protein 4
PCDHB13 protocadherin beta 13
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POM121 POM121 transmembrane nucleoporin
RANBP17 RAN binding protein 17
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF126P1 ring finger protein 126 pseudogene 1
ROM1 retinal outer segment membrane protein 1
RUSC2 RUN and SH3 domain containing 2
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SLC12A9 solute carrier family 12, member 9
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
STAG3 stromal antigen 3
STARD3 StAR-related lipid transfer (START) domain containing 3
TAOK1 TAO kinase 1
TCP10 t-complex 10
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TH tyrosine hydroxylase
TMEM121 transmembrane protein 121
TOR4A torsin family 4, member A
UNC119 unc-119 homolog (C. elegans)
UPK3B uroplakin 3B
USB1 U6 snRNA biogenesis 1
USP20 ubiquitin specific peptidase 20
VASH1 vasohibin 1
VPS9D1 VPS9 domain containing 1
WDR91 WD repeat domain 91
ZNF205 zinc finger protein 205
ZNF350 zinc finger protein 350
ZNRD1-AS1 ZNRD1 antisense RNA 1