levopropoxyphene-5503 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

192 genes differentially expressed following the levopropoxyphene-5503 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADGRL1 adhesion G protein-coupled receptor L1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ANAPC13 anaphase promoting complex subunit 13
ANGEL2 angel homolog 2 (Drosophila)
ANKLE2 ankyrin repeat and LEM domain containing 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
B9D2 B9 protein domain 2
BTD biotinidase
C14ORF79 chromosome 14 open reading frame 79
C1ORF54 chromosome 1 open reading frame 54
CASD1 CAS1 domain containing 1
CCNO cyclin O
CCNT2 cyclin T2
CCP110 centriolar coiled coil protein 110kDa
CD44 CD44 molecule (Indian blood group)
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CHMP6 charged multivesicular body protein 6
CLCN7 chloride channel, voltage-sensitive 7
CNTNAP2 contactin associated protein-like 2
COBLL1 cordon-bleu WH2 repeat protein-like 1
CRTC1 CREB regulated transcription coactivator 1
CYLD cylindromatosis (turban tumor syndrome)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPY19L1 dpy-19-like 1 (C. elegans)
DST dystonin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EVI5 ecotropic viral integration site 5
EVPL envoplakin
FBXO40 F-box protein 40
GAL galanin/GMAP prepropeptide
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNS glucosamine (N-acetyl)-6-sulfatase
GRB10 growth factor receptor-bound protein 10
GSTA1 glutathione S-transferase alpha 1
HSPG2 heparan sulfate proteoglycan 2
IGFBP5 insulin-like growth factor binding protein 5
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL4R interleukin 4 receptor
IPO8 importin 8
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
LAMC2 laminin, gamma 2
LEFTY1 left-right determination factor 1
LRRC61 leucine rich repeat containing 61
MCF2L MCF.2 cell line derived transforming sequence-like
MIA3 melanoma inhibitory activity family, member 3
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MOCS1 molybdenum cofactor synthesis 1
MUC3B mucin 3B, cell surface associated
NFYA nuclear transcription factor Y, alpha
NOX1 NADPH oxidase 1
NYNRIN NYN domain and retroviral integrase containing
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OSBPL2 oxysterol binding protein-like 2
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLD2 phospholipase D2
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PML promyelocytic leukemia
PRPH2 peripherin 2 (retinal degeneration, slow)
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RAD51B RAD51 paralog B
RNF39 ring finger protein 39
RORA RAR-related orphan receptor A
RRH retinal pigment epithelium-derived rhodopsin homolog
SAG S-antigen; retina and pineal gland (arrestin)
SAMD4A sterile alpha motif domain containing 4A
SAP30 Sin3A-associated protein, 30kDa
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SFTPC surfactant protein C
SGCE sarcoglycan, epsilon
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMTN smoothelin
SP1 Sp1 transcription factor
TADA2A transcriptional adaptor 2A
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TGFBR3 transforming growth factor, beta receptor III
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TREM1 triggering receptor expressed on myeloid cells 1
ZBTB22 zinc finger and BTB domain containing 22
ZNF277 zinc finger protein 277
ZNF287 zinc finger protein 287

decreased expression

Symbol Name
ACTL8 actin-like 8
ADTRP androgen-dependent TFPI-regulating protein
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARMC4 armadillo repeat containing 4
BAHD1 bromo adjacent homology domain containing 1
BTBD7 BTB (POZ) domain containing 7
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
CALCOCO1 calcium binding and coiled-coil domain 1
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDK20 cyclin-dependent kinase 20
CGREF1 cell growth regulator with EF-hand domain 1
CHKB choline kinase beta
CLDN9 claudin 9
CNPY3 canopy FGF signaling regulator 3
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRELD1 cysteine-rich with EGF-like domains 1
CRLF1 cytokine receptor-like factor 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
F2R coagulation factor II (thrombin) receptor
FAM189A2 family with sequence similarity 189, member A2
FBXO31 F-box protein 31
FGD1 FYVE, RhoGEF and PH domain containing 1
FPGS folylpolyglutamate synthase
FRMD1 FERM domain containing 1
GLRA1 glycine receptor, alpha 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BC histone cluster 1, H2bc
HOXC8 homeobox C8
IL2 interleukin 2
INO80D INO80 complex subunit D
INPPL1 inositol polyphosphate phosphatase-like 1
IRF1 interferon regulatory factor 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KRT24 keratin 24, type I
LAMP3 lysosomal-associated membrane protein 3
LIME1 Lck interacting transmembrane adaptor 1
LMBR1L limb development membrane protein 1-like
LOC390998 ribosomal protein L10 pseudogene
LPPR1 lipid phosphate phosphatase-related protein type 1
LRP5L low density lipoprotein receptor-related protein 5-like
LZTR1 leucine-zipper-like transcription regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAN2B1 mannosidase, alpha, class 2B, member 1
MAST3 microtubule associated serine/threonine kinase 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MED15 mediator complex subunit 15
MUC3A mucin 3A, cell surface associated
MXD3 MAX dimerization protein 3
MYLIP myosin regulatory light chain interacting protein
MYO1F myosin IF
NHEJ1 nonhomologous end-joining factor 1
NIPAL2 NIPA-like domain containing 2
NPFFR1 neuropeptide FF receptor 1
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PECR peroxisomal trans-2-enoyl-CoA reductase
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
QPCT glutaminyl-peptide cyclotransferase
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB4B RAB4B, member RAS oncogene family
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RIN1 Ras and Rab interactor 1
RNF126P1 ring finger protein 126 pseudogene 1
RPH3AL rabphilin 3A-like (without C2 domains)
RUSC2 RUN and SH3 domain containing 2
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SH3BGR SH3 domain binding glutamate-rich protein
SIL1 SIL1 nucleotide exchange factor
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
STK16 serine/threonine kinase 16
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TRIM36 tripartite motif containing 36
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
USP27X ubiquitin specific peptidase 27, X-linked
ZNF510 zinc finger protein 510
ZNF623 zinc finger protein 623
ZNF652 zinc finger protein 652
ZNF665 zinc finger protein 665
ZNF675 zinc finger protein 675