| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the lidocaine-1499 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| ACSL6 | acyl-CoA synthetase long-chain family member 6 |
| ACTN2 | actinin, alpha 2 |
| AHCYL1 | adenosylhomocysteinase-like 1 |
| ALOX15 | arachidonate 15-lipoxygenase |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ATG3 | autophagy related 3 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BIN1 | bridging integrator 1 |
| BTG2 | BTG family, member 2 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCDC57 | coiled-coil domain containing 57 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CCNO | cyclin O |
| CLEC11A | C-type lectin domain family 11, member A |
| CREB1 | cAMP responsive element binding protein 1 |
| DIEXF | digestive organ expansion factor homolog (zebrafish) |
| DLX2 | distal-less homeobox 2 |
| EHD2 | EH-domain containing 2 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
| EMID1 | EMI domain containing 1 |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| F2R | coagulation factor II (thrombin) receptor |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAAH | fatty acid amide hydrolase |
| FBLN1 | fibulin 1 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO11 | F-box protein 11 |
| FBXO21 | F-box protein 21 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FOSL1 | FOS-like antigen 1 |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| IFT27 | intraflagellar transport 27 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IGL | immunoglobulin lambda locus |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IQCG | IQ motif containing G |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIF13A | kinesin family member 13A |
| KLF9 | Kruppel-like factor 9 |
| KLHL29 | kelch-like family member 29 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LAT2 | linker for activation of T cells family, member 2 |
| LMAN1 | lectin, mannose-binding, 1 |
| LOC729164 | hCG1732469 |
| LRRC23 | leucine rich repeat containing 23 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MMP25 | matrix metallopeptidase 25 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTA2 | metastasis associated 1 family, member 2 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MZT2B | mitotic spindle organizing protein 2B |
| NDRG2 | NDRG family member 2 |
| NKRF | NFKB repressing factor |
| NRF1 | nuclear respiratory factor 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| PCDH17 | protocadherin 17 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PORCN | porcupine homolog (Drosophila) |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRA | protein tyrosine phosphatase, receptor type, A |
| RAB14 | RAB14, member RAS oncogene family |
| ROM1 | retinal outer segment membrane protein 1 |
| S100A2 | S100 calcium binding protein A2 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SDC3 | syndecan 3 |
| SELPLG | selectin P ligand |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SMAD3 | SMAD family member 3 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SRRT | serrate, RNA effector molecule |
| TAOK1 | TAO kinase 1 |
| TAOK2 | TAO kinase 2 |
| TBC1D17 | TBC1 domain family, member 17 |
| TCF12 | transcription factor 12 |
| TGFB2 | transforming growth factor, beta 2 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMPRSS3 | transmembrane protease, serine 3 |
| TWF2 | twinfilin actin binding protein 2 |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VN1R1 | vomeronasal 1 receptor 1 |
| WDR33 | WD repeat domain 33 |
| YY1 | YY1 transcription factor |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ABHD14A | abhydrolase domain containing 14A |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AZI2 | 5-azacytidine induced 2 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CAPN5 | calpain 5 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CD302 | CD302 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CEP70 | centrosomal protein 70kDa |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLK1 | CDC-like kinase 1 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CTAGE9 | CTAGE family, member 9 |
| DUSP2 | dual specificity phosphatase 2 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| FANCC | Fanconi anemia, complementation group C |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FEM1C | fem-1 homolog c (C. elegans) |
| FLJ22184 | |
| FOXN2 | forkhead box N2 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GPATCH2L | G patch domain containing 2-like |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| ICK | intestinal cell (MAK-like) kinase |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFT22 | intraflagellar transport 22 |
| IRF6 | interferon regulatory factor 6 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KIZ | kizuna centrosomal protein |
| LIN7A | lin-7 homolog A (C. elegans) |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LOC257152 | uncharacterized LOC257152 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 |
| MB | myoglobin |
| MCOLN1 | mucolipin 1 |
| MCOLN3 | mucolipin 3 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDRG4 | NDRG family member 4 |
| NKX3-2 | NK3 homeobox 2 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHA9 | protocadherin alpha 9 |
| PLA2G10 | phospholipase A2, group X |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PMCH | pro-melanin-concentrating hormone |
| PMM1 | phosphomannomutase 1 |
| PPCS | phosphopantothenoylcysteine synthetase |
| PRKCE | protein kinase C, epsilon |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PTK6 | protein tyrosine kinase 6 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF113A | ring finger protein 113A |
| RNF43 | ring finger protein 43 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| SH2B3 | SH2B adaptor protein 3 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SP1 | Sp1 transcription factor |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| SYT17 | synaptotagmin XVII |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TCTA | T-cell leukemia translocation altered |
| TDRD1 | tudor domain containing 1 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM14A | transmembrane protein 14A |
| TRAF5 | TNF receptor-associated factor 5 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TTC30A | tetratricopeptide repeat domain 30A |
| TUBA3C | tubulin, alpha 3c |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 |
| UBQLN4 | ubiquilin 4 |
| UFSP2 | UFM1-specific peptidase 2 |
| USP19 | ubiquitin specific peptidase 19 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF16 | zinc finger protein 16 |
| ZNF205 | zinc finger protein 205 |
| ZNF423 | zinc finger protein 423 |
| ZNF432 | zinc finger protein 432 |
| ZNF623 | zinc finger protein 623 |
| ZXDC | ZXD family zinc finger C |
