| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the lidocaine-1917 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ACOT11 | acyl-CoA thioesterase 11 |
| ACTN1 | actinin, alpha 1 |
| AEN | apoptosis enhancing nuclease |
| AHCYL1 | adenosylhomocysteinase-like 1 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 |
| ATM | ATM serine/threonine kinase |
| C20ORF27 | chromosome 20 open reading frame 27 |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CNPY3 | canopy FGF signaling regulator 3 |
| COL6A1 | collagen, type VI, alpha 1 |
| CPE | carboxypeptidase E |
| CSNK1G2 | casein kinase 1, gamma 2 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DCAF7 | DDB1 and CUL4 associated factor 7 |
| DNASE2 | deoxyribonuclease II, lysosomal |
| DUS2 | dihydrouridine synthase 2 |
| DUSP6 | dual specificity phosphatase 6 |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| EPRS | glutamyl-prolyl-tRNA synthetase |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| ESRRA | estrogen-related receptor alpha |
| EXOSC2 | exosome component 2 |
| F11R | F11 receptor |
| FBXO31 | F-box protein 31 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAS8 | growth arrest-specific 8 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GMDS | GDP-mannose 4,6-dehydratase |
| GRK6 | G protein-coupled receptor kinase 6 |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa |
| HDAC5 | histone deacetylase 5 |
| HEMK1 | HemK methyltransferase family member 1 |
| HIRIP3 | HIRA interacting protein 3 |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGFLR1 | IGF-like family receptor 1 |
| IGKV1D-13 | immunoglobulin kappa variable 1D-13 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KIAA0391 | KIAA0391 |
| KIAA1549L | KIAA1549-like |
| KLF6 | Kruppel-like factor 6 |
| KLHL3 | kelch-like family member 3 |
| KNTC1 | kinetochore associated 1 |
| KPTN | kaptin (actin binding protein) |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LSM12 | LSM12 homolog (S. cerevisiae) |
| MAP6D1 | MAP6 domain containing 1 |
| MBD3 | methyl-CpG binding domain protein 3 |
| MED1 | mediator complex subunit 1 |
| METRN | meteorin, glial cell differentiation regulator |
| MINK1 | misshapen-like kinase 1 |
| MXD4 | MAX dimerization protein 4 |
| MYL10 | myosin, light chain 10, regulatory |
| MYO9A | myosin IXA |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| PALM | paralemmin |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 |
| PDZD2 | PDZ domain containing 2 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PISD | phosphatidylserine decarboxylase |
| PLCE1 | phospholipase C, epsilon 1 |
| PMM1 | phosphomannomutase 1 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| PQBP1 | polyglutamine binding protein 1 |
| PREP | prolyl endopeptidase |
| PRKAB1 | protein kinase, AMP-activated, beta 1 non-catalytic subunit |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 |
| PTGES | prostaglandin E synthase |
| PYGB | phosphorylase, glycogen; brain |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RNF121 | ring finger protein 121 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SCCPDH | saccharopine dehydrogenase (putative) |
| SCYL3 | SCY1-like 3 (S. cerevisiae) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SUGP1 | SURP and G patch domain containing 1 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| THAP3 | THAP domain containing, apoptosis associated protein 3 |
| TRIM2 | tripartite motif containing 2 |
| USB1 | U6 snRNA biogenesis 1 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| WDR46 | WD repeat domain 46 |
| WRAP53 | WD repeat containing, antisense to TP53 |
| ZFR | zinc finger RNA binding protein |
| Symbol | Name |
|---|---|
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 |
| ABHD3 | abhydrolase domain containing 3 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARMC6 | armadillo repeat containing 6 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| AZI2 | 5-azacytidine induced 2 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| BRPF1 | bromodomain and PHD finger containing, 1 |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CASZ1 | castor zinc finger 1 |
| CCDC28A | coiled-coil domain containing 28A |
| CCDC68 | coiled-coil domain containing 68 |
| CCDC9 | coiled-coil domain containing 9 |
| CETN3 | centrin, EF-hand protein, 3 |
| CHEK2 | checkpoint kinase 2 |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| CISH | cytokine inducible SH2-containing protein |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CPOX | coproporphyrinogen oxidase |
| CTSD | cathepsin D |
| DCLRE1B | DNA cross-link repair 1B |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 |
| DMTN | dematin actin binding protein |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DOCK1 | dedicator of cytokinesis 1 |
| DUSP12 | dual specificity phosphatase 12 |
| EHD3 | EH-domain containing 3 |
| FAM193B | family with sequence similarity 193, member B |
| FAM50B | family with sequence similarity 50, member B |
| FEM1C | fem-1 homolog c (C. elegans) |
| GALR3 | galanin receptor 3 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GPR27 | G protein-coupled receptor 27 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
| HOXC6 | homeobox C6 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| IER3IP1 | immediate early response 3 interacting protein 1 |
| IL15RA | interleukin 15 receptor, alpha |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0894 | KIAA0894 protein |
| LGMN | legumain |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LRRC15 | leucine rich repeat containing 15 |
| MANSC1 | MANSC domain containing 1 |
| MINA | MYC induced nuclear antigen |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MRPL19 | mitochondrial ribosomal protein L19 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| MYL12B | myosin, light chain 12B, regulatory |
| NEK4 | NIMA-related kinase 4 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| OAT | ornithine aminotransferase |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OSTF1 | osteoclast stimulating factor 1 |
| OXR1 | oxidation resistance 1 |
| PAQR3 | progestin and adipoQ receptor family member III |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PDCD10 | programmed cell death 10 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPT1 | palmitoyl-protein thioesterase 1 |
| PTER | phosphotriesterase related |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| REXO4 | REX4, RNA exonuclease 4 homolog (S. cerevisiae) |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RWDD3 | RWD domain containing 3 |
| SH2B3 | SH2B adaptor protein 3 |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC35E3 | solute carrier family 35, member E3 |
| SOAT1 | sterol O-acyltransferase 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| TEFM | transcription elongation factor, mitochondrial |
| TIPRL | TOR signaling pathway regulator |
| TMEM53 | transmembrane protein 53 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRIM32 | tripartite motif containing 32 |
| TSPAN32 | tetraspanin 32 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TXNL4B | thioredoxin-like 4B |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| WDR11 | WD repeat domain 11 |
| ZBTB11 | zinc finger and BTB domain containing 11 |
| ZNF302 | zinc finger protein 302 |
