lidocaine-1999 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the lidocaine-1999 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABI2 abl-interactor 2
ACAA2 acetyl-CoA acyltransferase 2
ACP6 acid phosphatase 6, lysophosphatidic
ADARB1 adenosine deaminase, RNA-specific, B1
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AMN amnion associated transmembrane protein
ARFIP1 ADP-ribosylation factor interacting protein 1
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ASAP1-IT1 ASAP1 intronic transcript 1
ATAT1 alpha tubulin acetyltransferase 1
BBIP1 BBSome interacting protein 1
BCL7C B-cell CLL/lymphoma 7C
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
C14ORF1 chromosome 14 open reading frame 1
CADM3 cell adhesion molecule 3
CCNT1 cyclin T1
CCT8 chaperonin containing TCP1, subunit 8 (theta)
CD37 CD37 molecule
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CFAP74 cilia and flagella associated protein 74
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CPA4 carboxypeptidase A4
CYB561 cytochrome b561
CYHR1 cysteine/histidine-rich 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DACH1 dachshund family transcription factor 1
EPX eosinophil peroxidase
ETV1 ets variant 1
FAIM2 Fas apoptotic inhibitory molecule 2
FAM63A family with sequence similarity 63, member A
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
GFOD2 glucose-fructose oxidoreductase domain containing 2
GHRHR growth hormone releasing hormone receptor
H2AFX H2A histone family, member X
HFE hemochromatosis
HIST1H1E histone cluster 1, H1e
HNF1B HNF1 homeobox B
IL22RA1 interleukin 22 receptor, alpha 1
IL9R interleukin 9 receptor
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF5A kinesin family member 5A
KMT2A lysine (K)-specific methyltransferase 2A
KRT38 keratin 38, type I
LECT1 leukocyte cell derived chemotaxin 1
LOC647070 uncharacterized LOC647070
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LUZP1 leucine zipper protein 1
MAP2K6 mitogen-activated protein kinase kinase 6
MBIP MAP3K12 binding inhibitory protein 1
MID2 midline 2
MYL10 myosin, light chain 10, regulatory
NBL1 neuroblastoma 1, DAN family BMP antagonist
NF1 neurofibromin 1
NOP16 NOP16 nucleolar protein
NOS1 nitric oxide synthase 1 (neuronal)
NPFFR1 neuropeptide FF receptor 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NRGN neurogranin (protein kinase C substrate, RC3)
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OLFML2A olfactomedin-like 2A
OVGP1 oviductal glycoprotein 1, 120kDa
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKN1 protein kinase N1
POR P450 (cytochrome) oxidoreductase
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRB1 proline-rich protein BstNI subfamily 1
PRKCH protein kinase C, eta
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGES prostaglandin E synthase
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RBM12B RNA binding motif protein 12B
RGS16 regulator of G-protein signaling 16
RPL23AP32 ribosomal protein L23a pseudogene 32
RPL37A ribosomal protein L37a
RPS11 ribosomal protein S11
RSF1 remodeling and spacing factor 1
RUNDC3A RUN domain containing 3A
SEC31B SEC31 homolog B (S. cerevisiae)
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SRPK2 SRSF protein kinase 2
STRN4 striatin, calmodulin binding protein 4
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAS2R1 taste receptor, type 2, member 1
TMEM97 transmembrane protein 97
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
VAC14 Vac14 homolog (S. cerevisiae)
YLPM1 YLP motif containing 1
ZCCHC24 zinc finger, CCHC domain containing 24
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZMYND8 zinc finger, MYND-type containing 8
ZNF473 zinc finger protein 473

decreased expression

Symbol Name
AGO1 argonaute RISC catalytic component 1
ANAPC1 anaphase promoting complex subunit 1
APH1A APH1A gamma secretase subunit
APOC2 apolipoprotein C-II
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ASB13 ankyrin repeat and SOCS box containing 13
ASB6 ankyrin repeat and SOCS box containing 6
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
B3GNT1
BCL7B B-cell CLL/lymphoma 7B
BTNL3 butyrophilin-like 3
C11ORF48
C2ORF42 chromosome 2 open reading frame 42
CARD9 caspase recruitment domain family, member 9
CCDC9 coiled-coil domain containing 9
CCL2 chemokine (C-C motif) ligand 2
CDK5 cyclin-dependent kinase 5
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CRIPT cysteine-rich PDZ-binding protein
CRY1 cryptochrome circadian clock 1
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
FAM192A family with sequence similarity 192, member A
FHL3 four and a half LIM domains 3
GBAP1 glucosidase, beta, acid pseudogene 1
GBP2 guanylate binding protein 2, interferon-inducible
GLRX5 glutaredoxin 5
GMCL1 germ cell-less, spermatogenesis associated 1
GMEB1 glucocorticoid modulatory element binding protein 1
GMPPB GDP-mannose pyrophosphorylase B
GPATCH2 G patch domain containing 2
GPS1 G protein pathway suppressor 1
GSR glutathione reductase
H2BFS H2B histone family, member S (pseudogene)
HIRA histone cell cycle regulator
IFI30 interferon, gamma-inducible protein 30
ILKAP integrin-linked kinase-associated serine/threonine phosphatase
ITGAV integrin, alpha V
KIAA0196 KIAA0196
KIFC1 kinesin family member C1
KIZ kizuna centrosomal protein
KPTN kaptin (actin binding protein)
KRI1 KRI1 homolog (S. cerevisiae)
LGALS3 lectin, galactoside-binding, soluble, 3
LIAS lipoic acid synthetase
LRRK1 leucine-rich repeat kinase 1
MECR mitochondrial trans-2-enoyl-CoA reductase
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MRPL28 mitochondrial ribosomal protein L28
MT1HL1 metallothionein 1H-like 1
MYO19 myosin XIX
NABP2 nucleic acid binding protein 2
NADSYN1 NAD synthetase 1
NECAP2 NECAP endocytosis associated 2
NELFE negative elongation factor complex member E
NHEJ1 nonhomologous end-joining factor 1
NOL12 nucleolar protein 12
NUBP2 nucleotide binding protein 2
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PAK1IP1 PAK1 interacting protein 1
PIEZO1 piezo-type mechanosensitive ion channel component 1
PISD phosphatidylserine decarboxylase
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PNRC1 proline-rich nuclear receptor coactivator 1
POGK pogo transposable element with KRAB domain
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PTBP2 polypyrimidine tract binding protein 2
PYCR1 pyrroline-5-carboxylate reductase 1
RAB20 RAB20, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RIOK2 RIO kinase 2
RNF144A ring finger protein 144A
RNF220 ring finger protein 220
RNMTL1 RNA methyltransferase like 1
RRAGA Ras-related GTP binding A
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SH3GL1 SH3-domain GRB2-like 1
SKI SKI proto-oncogene
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLPI secretory leukocyte peptidase inhibitor
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TAC3 tachykinin 3
TERT telomerase reverse transcriptase
TMEM115 transmembrane protein 115
TMEM127 transmembrane protein 127
TMEM184B transmembrane protein 184B
TMEM251 transmembrane protein 251
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TRAIP TRAF interacting protein
U2AF1 U2 small nuclear RNA auxiliary factor 1
USB1 U6 snRNA biogenesis 1
YIPF1 Yip1 domain family, member 1
YPEL5 yippee-like 5 (Drosophila)
ZNF212 zinc finger protein 212
ZNF432 zinc finger protein 432
ZPR1 ZPR1 zinc finger