| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the lidocaine-4421 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX2 | acyl-CoA oxidase 2, branched chain |
| ADAM5 | ADAM metallopeptidase domain 5 (pseudogene) |
| AKAP1 | A kinase (PRKA) anchor protein 1 |
| ANO1 | anoctamin 1, calcium activated chloride channel |
| APP | amyloid beta (A4) precursor protein |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ATG10 | autophagy related 10 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CBX2 | chromobox homolog 2 |
| CD52 | CD52 molecule |
| CEP41 | centrosomal protein 41kDa |
| COL6A1 | collagen, type VI, alpha 1 |
| COL8A2 | collagen, type VIII, alpha 2 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CTNS | cystinosin, lysosomal cystine transporter |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DENND3 | DENN/MADD domain containing 3 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DOK5 | docking protein 5 |
| DYM | dymeclin |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FAM105A | family with sequence similarity 105, member A |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FHL1 | four and a half LIM domains 1 |
| GAS7 | growth arrest-specific 7 |
| GM2A | GM2 ganglioside activator |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR161 | G protein-coupled receptor 161 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRPR | gastrin-releasing peptide receptor |
| GSPT1 | G1 to S phase transition 1 |
| HAND1 | heart and neural crest derivatives expressed 1 |
| HEMK1 | HemK methyltransferase family member 1 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HOXA11 | homeobox A11 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL21 | interleukin 21 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| LAT2 | linker for activation of T cells family, member 2 |
| LIMK1 | LIM domain kinase 1 |
| MAG | myelin associated glycoprotein |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| METTL16 | methyltransferase like 16 |
| MLXIP | MLX interacting protein |
| NDRG2 | NDRG family member 2 |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NPY | neuropeptide Y |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PARP11 | poly (ADP-ribose) polymerase family, member 11 |
| PCBP3 | poly(rC) binding protein 3 |
| PCDHA5 | protocadherin alpha 5 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHTF2 | putative homeodomain transcription factor 2 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| RBBP9 | retinoblastoma binding protein 9 |
| RHBDL1 | rhomboid, veinlet-like 1 (Drosophila) |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RUNX1 | runt-related transcription factor 1 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SECTM1 | secreted and transmembrane 1 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SNCAIP | synuclein, alpha interacting protein |
| SOAT2 | sterol O-acyltransferase 2 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| STAB2 | stabilin 2 |
| STK4 | serine/threonine kinase 4 |
| TECPR2 | tectonin beta-propeller repeat containing 2 |
| TMEM63A | transmembrane protein 63A |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TPM3 | tropomyosin 3 |
| TTC39A | tetratricopeptide repeat domain 39A |
| USP29 | ubiquitin specific peptidase 29 |
| UTF1 | undifferentiated embryonic cell transcription factor 1 |
| VWA5A | von Willebrand factor A domain containing 5A |
| WAPAL | wings apart-like homolog (Drosophila) |
| ZNF235 | zinc finger protein 235 |
| ZNF589 | zinc finger protein 589 |
| ZNF702P | zinc finger protein 702, pseudogene |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| BAX | BCL2-associated X protein |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CASZ1 | castor zinc finger 1 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC64 | coiled-coil domain containing 64 |
| CCNO | cyclin O |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CNTNAP1 | contactin associated protein 1 |
| CPNE7 | copine VII |
| CRYGC | crystallin, gamma C |
| CXXC4 | CXXC finger protein 4 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DGKQ | diacylglycerol kinase, theta 110kDa |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERCC2 | excision repair cross-complementation group 2 |
| GAS2 | growth arrest-specific 2 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPC3 | glypican 3 |
| GRM6 | glutamate receptor, metabotropic 6 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HHAT | hedgehog acyltransferase |
| HIRA | histone cell cycle regulator |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3F | histone cluster 1, H3f |
| HMOX1 | heme oxygenase 1 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KLHL25 | kelch-like family member 25 |
| LOXL3 | lysyl oxidase-like 3 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAOB | monoamine oxidase B |
| MAP1S | microtubule-associated protein 1S |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MEGF6 | multiple EGF-like-domains 6 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MMP3 | matrix metallopeptidase 3 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MUC3A | mucin 3A, cell surface associated |
| NEUROD1 | neuronal differentiation 1 |
| NEUROD4 | neuronal differentiation 4 |
| NKX2-5 | NK2 homeobox 5 |
| NKX3-2 | NK3 homeobox 2 |
| NOTCH4 | notch 4 |
| NPR3 | natriuretic peptide receptor 3 |
| NPY4R | neuropeptide Y receptor Y4 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| NYNRIN | NYN domain and retroviral integrase containing |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PCDHB12 | protocadherin beta 12 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDZD2 | PDZ domain containing 2 |
| PHOX2A | paired-like homeobox 2a |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RORC | RAR-related orphan receptor C |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| TAOK1 | TAO kinase 1 |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TEP1 | telomerase-associated protein 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TNNI3 | troponin I type 3 (cardiac) |
| TPSG1 | tryptase gamma 1 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSGA10 | testis specific, 10 |
| UPP1 | uridine phosphorylase 1 |
| VIM | vimentin |
| WDR33 | WD repeat domain 33 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XDH | xanthine dehydrogenase |
| XYLT2 | xylosyltransferase II |
| ZNF652 | zinc finger protein 652 |
| ZNF721 | zinc finger protein 721 |
