lidoflazine-3201 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the lidoflazine-3201 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ANTXR1 anthrax toxin receptor 1
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGAP33 Rho GTPase activating protein 33
ATG10 autophagy related 10
AZU1 azurocidin 1
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BLVRA biliverdin reductase A
C10ORF12 chromosome 10 open reading frame 12
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC71 coiled-coil domain containing 71
CCRL2 chemokine (C-C motif) receptor-like 2
CEP295 centrosomal protein 295kDa
CES1 carboxylesterase 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPNE7 copine VII
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CST4 cystatin S
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DDO D-aspartate oxidase
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DSPP dentin sialophosphoprotein
DUSP10 dual specificity phosphatase 10
EPYC epiphycan
ERP44 endoplasmic reticulum protein 44
FBN2 fibrillin 2
FGF1 fibroblast growth factor 1 (acidic)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GRM7 glutamate receptor, metabotropic 7
GSDMB gasdermin B
HAMP hepcidin antimicrobial peptide
HIST2H2AA3 histone cluster 2, H2aa3
HNF4A hepatocyte nuclear factor 4, alpha
HOXB3 homeobox B3
ICAM1 intercellular adhesion molecule 1
ING4 inhibitor of growth family, member 4
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDM5B lysine (K)-specific demethylase 5B
KLRB1 killer cell lectin-like receptor subfamily B, member 1
LARP7 La ribonucleoprotein domain family, member 7
LDHAL6B lactate dehydrogenase A-like 6B
LIG3 ligase III, DNA, ATP-dependent
MBD3 methyl-CpG binding domain protein 3
MED31 mediator complex subunit 31
MERTK MER proto-oncogene, tyrosine kinase
NCOR2 nuclear receptor corepressor 2
NEFM neurofilament, medium polypeptide
NME5 NME/NM23 family member 5
NPR3 natriuretic peptide receptor 3
NRP2 neuropilin 2
OSMR oncostatin M receptor
PCDH12 protocadherin 12
PDLIM5 PDZ and LIM domain 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PIGR polymeric immunoglobulin receptor
PIWIL2 piwi-like RNA-mediated gene silencing 2
PLG plasminogen
PLLP plasmolipin
PLTP phospholipid transfer protein
PRB3 proline-rich protein BstNI subfamily 3
PRSS21 protease, serine, 21 (testisin)
PSD4 pleckstrin and Sec7 domain containing 4
PTGDR2 prostaglandin D2 receptor 2
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RPL35A ribosomal protein L35a
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
SAMD4A sterile alpha motif domain containing 4A
SCN2B sodium channel, voltage gated, type II beta subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT5 sirtuin 5
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
STAT5A signal transducer and activator of transcription 5A
STEAP4 STEAP family member 4
STOM stomatin
STS steroid sulfatase (microsomal), isozyme S
TCF12 transcription factor 12
TCP10L t-complex 10-like
TFR2 transferrin receptor 2
TMPRSS6 transmembrane protease, serine 6
TRPC3 transient receptor potential cation channel, subfamily C, member 3
UBOX5 U-box domain containing 5
YBX3 Y box binding protein 3
ZBTB7A zinc finger and BTB domain containing 7A
ZFAND5 zinc finger, AN1-type domain 5
ZNF208 zinc finger protein 208
ZNF814 zinc finger protein 814

decreased expression

Symbol Name
ADCK4 aarF domain containing kinase 4
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ANXA2P3 annexin A2 pseudogene 3
AOC2 amine oxidase, copper containing 2 (retina-specific)
ART1 ADP-ribosyltransferase 1
C11ORF80 chromosome 11 open reading frame 80
C2ORF27A chromosome 2 open reading frame 27A
C7ORF43 chromosome 7 open reading frame 43
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAMKV CaM kinase-like vesicle-associated
CARF calcium responsive transcription factor
CCNK cyclin K
CD53 CD53 molecule
CD82 CD82 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHRM3 cholinergic receptor, muscarinic 3
CLCN5 chloride channel, voltage-sensitive 5
CLIC2 chloride intracellular channel 2
CXCR2 chemokine (C-X-C motif) receptor 2
DENND4A DENN/MADD domain containing 4A
DENND5B DENN/MADD domain containing 5B
EMID1 EMI domain containing 1
EPHA2 EPH receptor A2
ERCC2 excision repair cross-complementation group 2
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGL1 fibrinogen-like 1
FLCN folliculin
FLJ21369 uncharacterized protein FLJ21369
FLRT3 fibronectin leucine rich transmembrane protein 3
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GAMT guanidinoacetate N-methyltransferase
GBP2 guanylate binding protein 2, interferon-inducible
GEMIN8 gem (nuclear organelle) associated protein 8
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPX1 glutathione peroxidase 1
HIST1H2BI histone cluster 1, H2bi
HSPA1L heat shock 70kDa protein 1-like
HYAL3 hyaluronoglucosaminidase 3
IDI2-AS1 IDI2 antisense RNA 1
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCTD7 potassium channel tetramerization domain containing 7
KRTAP2-4 keratin associated protein 2-4
LATS1 large tumor suppressor kinase 1
LDHB lactate dehydrogenase B
LPAR4 lysophosphatidic acid receptor 4
LYZ lysozyme
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MATK megakaryocyte-associated tyrosine kinase
MCC mutated in colorectal cancers
MCOLN1 mucolipin 1
MPO myeloperoxidase
MUC3A mucin 3A, cell surface associated
NDRG1 N-myc downstream regulated 1
NEK11 NIMA-related kinase 11
NLRX1 NLR family member X1
NNAT neuronatin
NRSN2 neurensin 2
NSD1 nuclear receptor binding SET domain protein 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OVGP1 oviductal glycoprotein 1, 120kDa
PACS1 phosphofurin acidic cluster sorting protein 1
PADI1 peptidyl arginine deiminase, type I
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PSAT1 phosphoserine aminotransferase 1
PVRL3 poliovirus receptor-related 3
RAD54L2 RAD54-like 2 (S. cerevisiae)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RELN reelin
RNF122 ring finger protein 122
RNF43 ring finger protein 43
SCNN1B sodium channel, non voltage gated 1 beta subunit
SLC12A8 solute carrier family 12, member 8
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SRGN serglycin
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUN2 Sad1 and UNC84 domain containing 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D17 TBC1 domain family, member 17
TCP10 t-complex 10
TMEM180 transmembrane protein 180
TPCN1 two pore segment channel 1
ULBP2 UL16 binding protein 2
VIM vimentin
WDR62 WD repeat domain 62
WDR91 WD repeat domain 91
WLS wntless Wnt ligand secretion mediator
WNT10B wingless-type MMTV integration site family, member 10B
ZBTB39 zinc finger and BTB domain containing 39
ZNF137P zinc finger protein 137, pseudogene
ZNF230 zinc finger protein 230
ZNF304 zinc finger protein 304
ZSCAN2 zinc finger and SCAN domain containing 2