lidoflazine-5804 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the lidoflazine-5804 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACSS3 acyl-CoA synthetase short-chain family member 3
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
AFF1 AF4/FMR2 family, member 1
AKAP5 A kinase (PRKA) anchor protein 5
ALK anaplastic lymphoma receptor tyrosine kinase
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARSD arylsulfatase D
ASMT acetylserotonin O-methyltransferase
BCL6 B-cell CLL/lymphoma 6
C1S complement component 1, s subcomponent
C7ORF69 chromosome 7 open reading frame 69
C9ORF9 chromosome 9 open reading frame 9
CA5B carbonic anhydrase VB, mitochondrial
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CADM4 cell adhesion molecule 4
CARD14 caspase recruitment domain family, member 14
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CASQ2 calsequestrin 2 (cardiac muscle)
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD177 CD177 molecule
CD209 CD209 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLCN7 chloride channel, voltage-sensitive 7
COL9A2 collagen, type IX, alpha 2
CRP C-reactive protein, pentraxin-related
CRYGD crystallin, gamma D
CXCR6 chemokine (C-X-C motif) receptor 6
CXORF21 chromosome X open reading frame 21
DDIT3 DNA-damage-inducible transcript 3
DFNB31 deafness, autosomal recessive 31
DOCK6 dedicator of cytokinesis 6
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELL elongation factor RNA polymerase II
FLT3LG fms-related tyrosine kinase 3 ligand
FLT4 fms-related tyrosine kinase 4
FOXN3 forkhead box N3
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GK glycerol kinase
GK3P glycerol kinase 3 pseudogene
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPNMB glycoprotein (transmembrane) nmb
GPR85 G protein-coupled receptor 85
GRIK5 glutamate receptor, ionotropic, kainate 5
HFE hemochromatosis
HLA-DMB major histocompatibility complex, class II, DM beta
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IL36A interleukin 36, alpha
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KLF4 Kruppel-like factor 4 (gut)
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAMA4 laminin, alpha 4
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC1720 dihydrofolate reductase pseudogene
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAPK14 mitogen-activated protein kinase 14
MFAP3 microfibrillar-associated protein 3
MMP25 matrix metallopeptidase 25
MUC5B mucin 5B, oligomeric mucus/gel-forming
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OR1F1 olfactory receptor, family 1, subfamily F, member 1
PAPPA2 pappalysin 2
PDGFA platelet-derived growth factor alpha polypeptide
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PID1 phosphotyrosine interaction domain containing 1
PIPOX pipecolic acid oxidase
PLCL2 phospholipase C-like 2
PRKCQ protein kinase C, theta
RAD51B RAD51 paralog B
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RPL35A ribosomal protein L35a
RPS4Y1 ribosomal protein S4, Y-linked 1
RSU1 Ras suppressor protein 1
SARM1 sterile alpha and TIR motif containing 1
SCARF1 scavenger receptor class F, member 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SIGLEC8 sialic acid binding Ig-like lectin 8
SIX3 SIX homeobox 3
STK17A serine/threonine kinase 17a
SYNGR3 synaptogyrin 3
TAGLN3 transgelin 3
TFEB transcription factor EB
THBS4 thrombospondin 4
TRD T cell receptor delta locus
VWA5A von Willebrand factor A domain containing 5A
ZBTB18 zinc finger and BTB domain containing 18
ZC2HC1C zinc finger, C2HC-type containing 1C
ZER1 zyg-11 related, cell cycle regulator
ZNF516 zinc finger protein 516
ZNF613 zinc finger protein 613
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
AGMAT agmatine ureohydrolase (agmatinase)
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BAHCC1 BAH domain and coiled-coil containing 1
BET1L Bet1 golgi vesicular membrane trafficking protein-like
CA5BP1 carbonic anhydrase VB pseudogene 1
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CEP295 centrosomal protein 295kDa
CFAP45 cilia and flagella associated protein 45
CISH cytokine inducible SH2-containing protein
CLCA1 chloride channel accessory 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CRYBA2 crystallin, beta A2
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DNAH7 dynein, axonemal, heavy chain 7
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EGR2 early growth response 2
ELP6 elongator acetyltransferase complex subunit 6
EXOC6B exocyst complex component 6B
FAM204A family with sequence similarity 204, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FAT4 FAT atypical cadherin 4
FBXL7 F-box and leucine-rich repeat protein 7
FER fer (fps/fes related) tyrosine kinase
FRS3 fibroblast growth factor receptor substrate 3
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR19 G protein-coupled receptor 19
GPR27 G protein-coupled receptor 27
GPX2 glutathione peroxidase 2
HIST1H1D histone cluster 1, H1d
HIST1H3C histone cluster 1, H3c
HSPA1L heat shock 70kDa protein 1-like
IFNA14 interferon, alpha 14
IFNA17 interferon, alpha 17
IPO8 importin 8
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KIAA1549L KIAA1549-like
KRT75 keratin 75, type II
LAMC3 laminin, gamma 3
LOC100287590 uncharacterized LOC100287590
LRP2 low density lipoprotein receptor-related protein 2
LRRC61 leucine rich repeat containing 61
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYRM9 LYR motif containing 9
LZTS3 leucine zipper, putative tumor suppressor family member 3
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MMRN2 multimerin 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NKX3-2 NK3 homeobox 2
NOL12 nucleolar protein 12
NOTCH1 notch 1
NTSR1 neurotensin receptor 1 (high affinity)
ODF2 outer dense fiber of sperm tails 2
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PDE8B phosphodiesterase 8B
PHF14 PHD finger protein 14
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PODXL2 podocalyxin-like 2
PRAMEF11 PRAME family member 11
PRPH peripherin
PTDSS2 phosphatidylserine synthase 2
RAD54L2 RAD54-like 2 (S. cerevisiae)
RETN resistin
RGS19 regulator of G-protein signaling 19
RIN1 Ras and Rab interactor 1
RNF2 ring finger protein 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SAMD9 sterile alpha motif domain containing 9
SCHIP1 schwannomin interacting protein 1
SGK2 serum/glucocorticoid regulated kinase 2
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SP1 Sp1 transcription factor
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STRN striatin, calmodulin binding protein
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
THRB thyroid hormone receptor, beta
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM2 transmembrane protein 2
TMEM209 transmembrane protein 209
TMEM53 transmembrane protein 53
TPCN1 two pore segment channel 1
TRABD TraB domain containing
UGT8 UDP glycosyltransferase 8
VEZT vezatin, adherens junctions transmembrane protein
ZNF205 zinc finger protein 205
ZNF358 zinc finger protein 358
ZNF428 zinc finger protein 428
ZNF667 zinc finger protein 667
ZNF671 zinc finger protein 671
ZNF74 zinc finger protein 74
ZNF76 zinc finger protein 76