life Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

377 genes co-occuring with the biological term life in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ACE angiotensin I converting enzyme
ACP1 acid phosphatase 1, soluble
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ACVRL1 activin A receptor type II-like 1
ADAM33 ADAM metallopeptidase domain 33
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRBK1 adrenergic, beta, receptor kinase 1
AFP alpha-fetoprotein
AGO2 argonaute RISC catalytic component 2
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AIRE autoimmune regulator
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALPP alkaline phosphatase, placental
AMH anti-Mullerian hormone
ANGPT1 angiopoietin 1
APOA1 apolipoprotein A-I
APOD apolipoprotein D
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AQP2 aquaporin 2 (collecting duct)
ARF4 ADP-ribosylation factor 4
ARF5 ADP-ribosylation factor 5
ATRIP ATR interacting protein
AVPR1A arginine vasopressin receptor 1A
BAG1 BCL2-associated athanogene
BAG3 BCL2-associated athanogene 3
BAIAP2 BAI1-associated protein 2
BAX BCL2-associated X protein
BCAP31 B-cell receptor-associated protein 31
BDKRB2 bradykinin receptor B2
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRD4 bromodomain containing 4
BST1 bone marrow stromal cell antigen 1
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CCL11 chemokine (C-C motif) ligand 11
CCL22 chemokine (C-C motif) ligand 22
CCR10 chemokine (C-C motif) receptor 10
CCR9 chemokine (C-C motif) receptor 9
CD34 CD34 molecule
CD38 CD38 molecule
CD40LG CD40 ligand
CD81 CD81 molecule
CDC25A cell division cycle 25A
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDKL5 cyclin-dependent kinase-like 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CERS1 ceramide synthase 1
CETP cholesteryl ester transfer protein, plasma
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHAT choline O-acetyltransferase
CHEK2 checkpoint kinase 2
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLDN3 claudin 3
CLU clusterin
COCH cochlin
COL3A1 collagen, type III, alpha 1
COL4A1 collagen, type IV, alpha 1
COMT catechol-O-methyltransferase
CPT2 carnitine palmitoyltransferase 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRHR1 corticotropin releasing hormone receptor 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRP C-reactive protein, pentraxin-related
CRYAA crystallin, alpha A
CST3 cystatin C
CTSB cathepsin B
CXCL8 chemokine (C-X-C motif) ligand 8
CYBB cytochrome b-245, beta polypeptide
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
DAGLA diacylglycerol lipase, alpha
DCX doublecortin
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DHH desert hedgehog
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DIO3 deiodinase, iodothyronine, type III
DISC1 disrupted in schizophrenia 1
DLX3 distal-less homeobox 3
DNAL1 dynein, axonemal, light chain 1
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
EDN1 endothelin 1
EEF2K eukaryotic elongation factor 2 kinase
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
ENDOG endonuclease G
EPAS1 endothelial PAS domain protein 1
EPO erythropoietin
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
EXO1 exonuclease 1
F2 coagulation factor II (thrombin)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FBN1 fibrillin 1
FGF21 fibroblast growth factor 21
FGF23 fibroblast growth factor 23
FLG filaggrin
FLT3 fms-related tyrosine kinase 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FTO fat mass and obesity associated
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAL galanin/GMAP prepropeptide
GALR1 galanin receptor 1
GALR2 galanin receptor 2
GALR3 galanin receptor 3
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GDF5 growth differentiation factor 5
GDNF glial cell derived neurotrophic factor
GH1 growth hormone 1
GHR growth hormone receptor
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GJB2 gap junction protein, beta 2, 26kDa
GRHL2 grainyhead-like 2 (Drosophila)
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRP gastrin-releasing peptide
GSDMA gasdermin A
GSK3B glycogen synthase kinase 3 beta
GSR glutathione reductase
GSTP1 glutathione S-transferase pi 1
GUCA1A guanylate cyclase activator 1A (retina)
GUSB glucuronidase, beta
HBA1 hemoglobin, alpha 1
HCP5 HLA complex P5 (non-protein coding)
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC4 histone deacetylase 4
HHIP hedgehog interacting protein
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-C major histocompatibility complex, class I, C
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HNF1A HNF1 homeobox A
HNF1B HNF1 homeobox B
HNF4A hepatocyte nuclear factor 4, alpha
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HOXA5 homeobox A5
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
HSF1 heat shock transcription factor 1
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNW1 interferon, omega 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGFBP1 insulin-like growth factor binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IHH indian hedgehog
IL10 interleukin 10
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL21 interleukin 21
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL6 interleukin 6
IMPG2 interphotoreceptor matrix proteoglycan 2
INS insulin
IRF1 interferon regulatory factor 1
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JUN jun proto-oncogene
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KL klotho
KLK3 kallikrein-related peptidase 3
KRT16 keratin 16, type I
KRT19 keratin 19, type I
LDB3 LIM domain binding 3
LEP leptin
LEPQTL1 Leptin, serum levels of
LGALS3 lectin, galactoside-binding, soluble, 3
LPL lipoprotein lipase
LRP1 low density lipoprotein receptor-related protein 1
LRRK2 leucine-rich repeat kinase 2
LTA lymphotoxin alpha
MAOA monoamine oxidase A
MAP4 microtubule-associated protein 4
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAPT microtubule-associated protein tau
MAVS mitochondrial antiviral signaling protein
MC4R melanocortin 4 receptor
MECP2 methyl CpG binding protein 2
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR122 microRNA 122
MIR145 microRNA 145
MIR190A microRNA 190a
MKI67 marker of proliferation Ki-67
MOG myelin oligodendrocyte glycoprotein
MPL MPL proto-oncogene, thrombopoietin receptor
MPO myeloperoxidase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MT-TV tRNA
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTTP microsomal triglyceride transfer protein
MUTYH mutY homolog
MYBPC3 myosin binding protein C, cardiac
MYO7A myosin VIIA
NAMPT nicotinamide phosphoribosyltransferase
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCAM1 neural cell adhesion molecule 1
NCR3 natural cytotoxicity triggering receptor 3
NDRG2 NDRG family member 2
NEU1 sialidase 1 (lysosomal sialidase)
NEU3 sialidase 3 (membrane sialidase)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOTCH1 notch 1
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPPC natriuretic peptide C
NPSR1 neuropeptide S receptor 1
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NR5A1 nuclear receptor subfamily 5, group A, member 1
NTF3 neurotrophin 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OGG1 8-oxoguanine DNA glycosylase
OPRM1 opioid receptor, mu 1
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
OXT oxytocin/neurophysin I prepropeptide
OXTR oxytocin receptor
PAH phenylalanine hydroxylase
PER2 period circadian clock 2
PGM1 phosphoglucomutase 1
PICALM phosphatidylinositol binding clathrin assembly protein
PIDD1 p53-induced death domain protein 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLIN3 perilipin 3
PON1 paraoxonase 1
POU1F1 POU class 1 homeobox 1
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKCD protein kinase C, delta
PRKCH protein kinase C, eta
PRPF19 pre-mRNA processing factor 19
PSEN1 presenilin 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAB1A RAB1A, member RAS oncogene family
RAB27A RAB27A, member RAS oncogene family
RAPSN receptor-associated protein of the synapse
RARB retinoic acid receptor, beta
RBX1 ring-box 1, E3 ubiquitin protein ligase
RELN reelin
RET ret proto-oncogene
RETN resistin
RGR retinal G protein coupled receptor
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNASE3 ribonuclease, RNase A family, 3
RPE65 retinal pigment epithelium-specific protein 65kDa
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1
RPS27 ribosomal protein S27
RPS3 ribosomal protein S3
RYR1 ryanodine receptor 1 (skeletal)
RYR3 ryanodine receptor 3
SELL selectin L
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFTPC surfactant protein C
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHH sonic hedgehog
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIRT1 sirtuin 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SOD1 superoxide dismutase 1, soluble
SOX9 SRY (sex determining region Y)-box 9
SPAST spastin
SPTB spectrin, beta, erythrocytic
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SRFBP1 serum response factor binding protein 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIM2 stromal interaction molecule 2
STOM stomatin
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TBC1D20 TBC1 domain family, member 20
TCF4 transcription factor 4
TEC tec protein tyrosine kinase
TEK TEK tyrosine kinase, endothelial
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TH tyrosine hydroxylase
THBS1 thrombospondin 1
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR9 toll-like receptor 9
TMSB10 thymosin beta 10
TMSB4X thymosin beta 4, X-linked
TNF tumor necrosis factor
TNPO3 transportin 3
TOR1B torsin family 1, member B (torsin B)
TP53 tumor protein p53
TPH2 tryptophan hydroxylase 2
TPM2 tropomyosin 2 (beta)
TRAF1 TNF receptor-associated factor 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TSLP thymic stromal lymphopoietin
TTBK2 tau tubulin kinase 2
TTR transthyretin
TXNIP thioredoxin interacting protein
UBASH3A ubiquitin associated and SH3 domain containing A
UBE3A ubiquitin protein ligase E3A
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6
UMOD uromodulin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
VTRNA2-1 vault RNA 2-1
WNT1 wingless-type MMTV integration site family, member 1
WNT16 wingless-type MMTV integration site family, member 16
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZAR1 zygote arrest 1