ligand-gated channel activity Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
Description Catalysis of the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts. (Gene Ontology, GO_0022834)
External Link http://amigo.geneontology.org/amigo/term/GO:0022834
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Genes

17 genes performing the ligand-gated channel activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
ANXA6 annexin A6
BEST1 bestrophin 1
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CNGA3 cyclic nucleotide gated channel alpha 3
CNGB1 cyclic nucleotide gated channel beta 1
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GPRIN1 G protein regulated inducer of neurite outgrowth 1
KCNK1 potassium channel, two pore domain subfamily K, member 1
KCNK2 potassium channel, two pore domain subfamily K, member 2
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
ZACN zinc activated ligand-gated ion channel