light Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description The photoperiod and type (e.g., natural, restricted wavelength) of light exposure. (Experimental Factor Ontology, EFO_0000568)
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Genes

450 genes co-occuring with the biological term light in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACHE acetylcholinesterase (Yt blood group)
ACKR3 atypical chemokine receptor 3
ADAM33 ADAM metallopeptidase domain 33
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADORA2A adenosine A2a receptor
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AICDA activation-induced cytidine deaminase
ALB albumin
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANGPT2 angiopoietin 2
ANGPTL3 angiopoietin-like 3
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANXA2 annexin A2
APC adenomatous polyposis coli
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
AQP2 aquaporin 2 (collecting duct)
AQP4 aquaporin 4
AR androgen receptor
ARL5B ADP-ribosylation factor-like 5B
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATG5 autophagy related 5
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
B2M beta-2-microglobulin
BAX BCL2-associated X protein
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BEST1 bestrophin 1
BIN1 bridging integrator 1
BIRC5 baculoviral IAP repeat containing 5
BPIFA1 BPI fold containing family A, member 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRD7 bromodomain containing 7
BTK Bruton agammaglobulinemia tyrosine kinase
BUB3 BUB3 mitotic checkpoint protein
C3 complement component 3
CACYBP calcyclin binding protein
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALY calcyon neuron-specific vesicular protein
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAT catalase
CBX5 chromobox homolog 5
CCND1 cyclin D1
CCND2 cyclin D2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDT1 chromatin licensing and DNA replication factor 1
CDYL chromodomain protein, Y-like
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK1 checkpoint kinase 1
CIRBP cold inducible RNA binding protein
CLTA clathrin, light chain A
CLTB clathrin, light chain B
CLTC clathrin, heavy chain (Hc)
CLU clusterin
CNGB1 cyclic nucleotide gated channel beta 1
CNPY2 canopy FGF signaling regulator 2
CNTF ciliary neurotrophic factor
COMT catechol-O-methyltransferase
CREBBP CREB binding protein
CRTC1 CREB regulated transcription coactivator 1
CRY1 cryptochrome circadian clock 1
CRYAB crystallin, alpha B
CRYGD crystallin, gamma D
CRYGS crystallin, gamma S
CTAG1B cancer/testis antigen 1B
CTF1 cardiotrophin 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSD cathepsin D
CTSE cathepsin E
CTSG cathepsin G
CTTN cortactin
CUBN cubilin (intrinsic factor-cobalamin receptor)
CXCR4 chemokine (C-X-C motif) receptor 4
CXORF67 chromosome X open reading frame 67
CYBA cytochrome b-245, alpha polypeptide
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2
DAXX death-domain associated protein
DCD dermcidin
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFB103B defensin, beta 103B
DHX36 DEAH (Asp-Glu-Ala-His) box polypeptide 36
DMPK dystrophia myotonica-protein kinase
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DRAM1 DNA-damage regulated autophagy modulator 1
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
DTNBP1 dystrobrevin binding protein 1
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYNLL1 dynein, light chain, LC8-type 1
DYNLRB1 dynein, light chain, roadblock-type 1
DYNLT1 dynein, light chain, Tctex-type 1
E2F1 E2F transcription factor 1
EBF1 early B-cell factor 1
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
ELAVL1 ELAV like RNA binding protein 1
ELF5 E74-like factor 5 (ets domain transcription factor)
ELL2 elongation factor, RNA polymerase II, 2
EP300 E1A binding protein p300
ERCC2 excision repair cross-complementation group 2
ERLEC1 endoplasmic reticulum lectin 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETV6 ets variant 6
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F10 coagulation factor X
F11 coagulation factor XI
F13A1 coagulation factor XIII, A1 polypeptide
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
F9 coagulation factor IX
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBXW8 F-box and WD repeat domain containing 8
FERMT2 fermitin family member 2
FGF7 fibroblast growth factor 7
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FRAS1 Fraser extracellular matrix complex subunit 1
FTH1 ferritin, heavy polypeptide 1
FTL ferritin, light polypeptide
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GDF15 growth differentiation factor 15
GDF3 growth differentiation factor 3
GHRL ghrelin/obestatin prepropeptide
GLTSCR2 glioma tumor suppressor candidate region gene 2
GNB5 guanine nucleotide binding protein (G protein), beta 5
GRM3 glutamate receptor, metabotropic 3
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GTF2H5 general transcription factor IIH, polypeptide 5
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
HAMP hepcidin antimicrobial peptide
HBA2 hemoglobin, alpha 2
HDAC6 histone deacetylase 6
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF3A hypoxia inducible factor 3, alpha subunit
HIP1 huntingtin interacting protein 1
HIP1R huntingtin interacting protein 1 related
HMOX1 heme oxygenase 1
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HOXD10 homeobox D10
HRAS Harvey rat sarcoma viral oncogene homolog
HSPG2 heparan sulfate proteoglycan 2
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNGR2 interferon gamma receptor 2 (interferon gamma transducer 1)
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP1 insulin-like growth factor binding protein 1
IGK immunoglobulin kappa locus
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL20 interleukin 20
IL21 interleukin 21
IL2RA interleukin 2 receptor, alpha
IL33 interleukin 33
IL36G interleukin 36, gamma
IL6 interleukin 6
INS insulin
IRF3 interferon regulatory factor 3
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JUN jun proto-oncogene
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KIF11 kinesin family member 11
KIF18A kinesin family member 18A
KIF5B kinesin family member 5B
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1
KIZ kizuna centrosomal protein
KLC1 kinesin light chain 1
KLF2 Kruppel-like factor 2
KNG1 kininogen 1
KRIT1 KRIT1, ankyrin repeat containing
KRT13 keratin 13, type I
KRT17 keratin 17, type I
L1CAM L1 cell adhesion molecule
LCN1 lipocalin 1
LEPR leptin receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LIMK1 LIM domain kinase 1
LINS lines homolog (Drosophila)
LMAN1 lectin, mannose-binding, 1
LMNA lamin A/C
LPIN2 lipin 2
LRP1 low density lipoprotein receptor-related protein 1
LRP2 low density lipoprotein receptor-related protein 2
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
M6PR mannose-6-phosphate receptor (cation dependent)
MAP1A microtubule-associated protein 1A
MAP1B microtubule-associated protein 1B
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAP1LC3C microtubule-associated protein 1 light chain 3 gamma
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAPK1 mitogen-activated protein kinase 1
MAPK8 mitogen-activated protein kinase 8
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPT microtubule-associated protein tau
MBL2 mannose-binding lectin (protein C) 2, soluble
MBTD1 mbt domain containing 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGMT O-6-methylguanine-DNA methyltransferase
MID1 midline 1
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR145 microRNA 145
MIR204 microRNA 204
MIR21 microRNA 21
MIR224 microRNA 224
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPLKIP M-phase specific PLK1 interacting protein
MPRIP myosin phosphatase Rho interacting protein
MRC1 mannose receptor, C type 1
MT3 metallothionein 3
MUC1 mucin 1, cell surface associated
MYBPC1 myosin binding protein C, slow type
MYBPC3 myosin binding protein C, cardiac
MYBPH myosin binding protein H
MYH14 myosin, heavy chain 14, non-muscle
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYH9 myosin, heavy chain 9, non-muscle
MYL1 myosin, light chain 1, alkali; skeletal, fast
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
MYLIP myosin regulatory light chain interacting protein
MYLK myosin light chain kinase
MYLK2 myosin light chain kinase 2
MYLK3 myosin light chain kinase 3
MYLK4 myosin light chain kinase family, member 4
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
MYO5A myosin VA (heavy chain 12, myoxin)
NAMPT nicotinamide phosphoribosyltransferase
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCAM1 neural cell adhesion molecule 1
NCF1C neutrophil cytosolic factor 1C pseudogene
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NEFL neurofilament, light polypeptide
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NF2 neurofibromin 2 (merlin)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NGFR nerve growth factor receptor
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NR1H3 nuclear receptor subfamily 1, group H, member 3
NTF3 neurotrophin 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUAK2 NUAK family, SNF1-like kinase, 2
NUCB1 nucleobindin 1
NUMB numb homolog (Drosophila)
OCRL oculocerebrorenal syndrome of Lowe
OLFM4 olfactomedin 4
OPN1LW opsin 1 (cone pigments), long-wave-sensitive
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
OPN4 opsin 4
ORAI1 ORAI calcium release-activated calcium modulator 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PARK2 parkin RBR E3 ubiquitin protein ligase
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PEBP1 phosphatidylethanolamine binding protein 1
PER2 period circadian clock 2
PER3 period circadian clock 3
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIP4K2A phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
PLA1A phospholipase A1 member A
PLAUR plasminogen activator, urokinase receptor
PMEL premelanosome protein
POLM polymerase (DNA directed), mu
POMC proopiomelanocortin
PON2 paraoxonase 2
POU5F1 POU class 5 homeobox 1
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRDX1 peroxiredoxin 1
PRDX4 peroxiredoxin 4
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKG1 protein kinase, cGMP-dependent, type I
PRNP prion protein
PROCR protein C receptor, endothelial
PSAP prosaposin
PSEN1 presenilin 1
PTCH1 patched 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTTG1 pituitary tumor-transforming 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD9A RAD9 homolog A (S. pombe)
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RB1 retinoblastoma 1
RDH12 retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
RDH8 retinol dehydrogenase 8 (all-trans)
RECQL4 RecQ protein-like 4
REEP1 receptor accessory protein 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RGS9BP regulator of G protein signaling 9 binding protein
RHEB Ras homolog enriched in brain
RHO rhodopsin
RHOA ras homolog family member A
RHOU ras homolog family member U
RIPK2 receptor-interacting serine-threonine kinase 2
RNF113A ring finger protein 113A
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPGR retinitis pigmentosa GTPase regulator
RPS25 ribosomal protein S25
RUNX1 runt-related transcription factor 1
RYR2 ryanodine receptor 2 (cardiac)
S100A10 S100 calcium binding protein A10
S100A4 S100 calcium binding protein A4
SALL3 spalt-like transcription factor 3
SCAP SREBF chaperone
SDC1 syndecan 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SIAH2 siah E3 ubiquitin protein ligase 2
SIRPA signal-regulatory protein alpha
SIRT1 sirtuin 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SMAD7 SMAD family member 7
SMN1 survival of motor neuron 1, telomeric
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNAI2 snail family zinc finger 2
SNAP25 synaptosomal-associated protein, 25kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCB synuclein, beta
SNCG synuclein, gamma (breast cancer-specific protein 1)
SNW1 SNW domain containing 1
SOD2 superoxide dismutase 2, mitochondrial
SOX2 SRY (sex determining region Y)-box 2
SPI1 Spi-1 proto-oncogene
SQSTM1 sequestosome 1
SREBF2 sterol regulatory element binding transcription factor 2
SRPK1 SRSF protein kinase 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK11 serine/threonine kinase 11
STX4 syntaxin 4
SYK spleen tyrosine kinase
SYNE2 spectrin repeat containing, nuclear envelope 2
TARDBP TAR DNA binding protein
TBC1D24 TBC1 domain family, member 24
TBX1 T-box 1
TBX21 T-box 21
TCF3 transcription factor 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TCTE3 t-complex-associated-testis-expressed 3
TERT telomerase reverse transcriptase
TF transferrin
TFAM transcription factor A, mitochondrial
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
TIMELESS timeless circadian clock
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TMEM27 transmembrane protein 27
TMPRSS15 transmembrane protease, serine 15
TNF tumor necrosis factor
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP73 tumor protein p73
TPP1 tripeptidyl peptidase I
TRIM21 tripartite motif containing 21
TRIT1 tRNA isopentenyltransferase 1
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TTR transthyretin
VDAC1 voltage-dependent anion channel 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
VPREB1 pre-B lymphocyte 1
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
VTN vitronectin
VWF von Willebrand factor
WNK1 WNK lysine deficient protein kinase 1
WRNIP1 Werner helicase interacting protein 1
WT1 Wilms tumor 1
XIST X inactive specific transcript (non-protein coding)
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YAP1 Yes-associated protein 1