lincomycin-5992 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the lincomycin-5992 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AK1 adenylate kinase 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARL1 ADP-ribosylation factor-like 1
AXIN1 axin 1
C3ORF18 chromosome 3 open reading frame 18
CA9 carbonic anhydrase IX
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCDC181 coiled-coil domain containing 181
CD177 CD177 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEP164 centrosomal protein 164kDa
CES3 carboxylesterase 3
CFAP45 cilia and flagella associated protein 45
CGA glycoprotein hormones, alpha polypeptide
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRABP1 cellular retinoic acid binding protein 1
CTNNA2 catenin (cadherin-associated protein), alpha 2
DAPK2 death-associated protein kinase 2
DCAF4 DDB1 and CUL4 associated factor 4
DOCK5 dedicator of cytokinesis 5
DOK4 docking protein 4
DSC2 desmocollin 2
DSG1 desmoglein 1
DUSP13 dual specificity phosphatase 13
DUSP9 dual specificity phosphatase 9
EDNRA endothelin receptor type A
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EPHB2 EPH receptor B2
EXO5 exonuclease 5
FLJ11292
FYB FYN binding protein
GGPS1 geranylgeranyl diphosphate synthase 1
GJA9 gap junction protein, alpha 9, 59kDa
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HFE hemochromatosis
HIPK3 homeodomain interacting protein kinase 3
HPGDS hematopoietic prostaglandin D synthase
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGHM immunoglobulin heavy constant mu
KIF13A kinesin family member 13A
KLF13 Kruppel-like factor 13
LAT2 linker for activation of T cells family, member 2
LATS1 large tumor suppressor kinase 1
LGALS4 lectin, galactoside-binding, soluble, 4
MAPK11 mitogen-activated protein kinase 11
MED25 mediator complex subunit 25
MOCS1 molybdenum cofactor synthesis 1
MTA2 metastasis associated 1 family, member 2
MUC4 mucin 4, cell surface associated
NCR2 natural cytotoxicity triggering receptor 2
NKAIN1 Na+/K+ transporting ATPase interacting 1
NNAT neuronatin
NPR1 natriuretic peptide receptor 1
NTF3 neurotrophin 3
NXPE3 neurexophilin and PC-esterase domain family, member 3
OPCML opioid binding protein/cell adhesion molecule-like
OTUD7B OTU deubiquitinase 7B
PCDHB17P protocadherin beta 17 pseudogene
PCDHB6 protocadherin beta 6
PCDHB8 protocadherin beta 8
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RASA3 RAS p21 protein activator 3
RSU1 Ras suppressor protein 1
S100A8 S100 calcium binding protein A8
SFRP1 secreted frizzled-related protein 1
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC17A2 solute carrier family 17, member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNN stannin
SOGA1 suppressor of glucose, autophagy associated 1
SRSF7 serine/arginine-rich splicing factor 7
SSX3 synovial sarcoma, X breakpoint 3
STAB2 stabilin 2
STS steroid sulfatase (microsomal), isozyme S
SUGP1 SURP and G patch domain containing 1
TAOK1 TAO kinase 1
TAS2R10 taste receptor, type 2, member 10
TNS1 tensin 1
TRIM21 tripartite motif containing 21
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
UTRN utrophin
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WIZ widely interspaced zinc finger motifs
WSCD1 WSC domain containing 1
YTHDC2 YTH domain containing 2
ZFP36L2 ZFP36 ring finger protein-like 2
ZFP64 ZFP64 zinc finger protein

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ABI3BP ABI family, member 3 (NESH) binding protein
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALAD aminolevulinate dehydratase
ALPK1 alpha-kinase 1
ALS2CL ALS2 C-terminal like
BFSP1 beaded filament structural protein 1, filensin
BMP15 bone morphogenetic protein 15
C19ORF40 chromosome 19 open reading frame 40
C7ORF69 chromosome 7 open reading frame 69
CAPG capping protein (actin filament), gelsolin-like
CAPN5 calpain 5
CARTPT CART prepropeptide
CCDC85C coiled-coil domain containing 85C
CCP110 centriolar coiled coil protein 110kDa
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CHRM3 cholinergic receptor, muscarinic 3
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CSF1R colony stimulating factor 1 receptor
CXXC4 CXXC finger protein 4
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGAT1 diacylglycerol O-acyltransferase 1
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
F8 coagulation factor VIII, procoagulant component
FAM120C family with sequence similarity 120C
GID4 GID complex subunit 4
GLI3 GLI family zinc finger 3
GRTP1 growth hormone regulated TBC protein 1
GUSBP3 glucuronidase, beta pseudogene 3
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INF2 inverted formin, FH2 and WH2 domain containing
INPPL1 inositol polyphosphate phosphatase-like 1
IQSEC2 IQ motif and Sec7 domain 2
ITPKB inositol-trisphosphate 3-kinase B
KIAA0355 KIAA0355
LINC00115 long intergenic non-protein coding RNA 115
LY6D lymphocyte antigen 6 complex, locus D
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MFAP2 microfibrillar-associated protein 2
MGC12488
MOCS3 molybdenum cofactor synthesis 3
MRAS muscle RAS oncogene homolog
MVP major vault protein
NACA2 nascent polypeptide-associated complex alpha subunit 2
NEUROD4 neuronal differentiation 4
NOD1 nucleotide-binding oligomerization domain containing 1
NUPR1 nuclear protein, transcriptional regulator, 1
ONECUT2 one cut homeobox 2
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OVOL1 ovo-like zinc finger 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHA6 protocadherin alpha 6
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POM121 POM121 transmembrane nucleoporin
PRICKLE3 prickle homolog 3 (Drosophila)
PROL1 proline rich, lacrimal 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBL1 retinoblastoma-like 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF2 ring finger protein 2
RNF43 ring finger protein 43
RPGR retinitis pigmentosa GTPase regulator
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUFY2 RUN and FYVE domain containing 2
SCAI suppressor of cancer cell invasion
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SND1-IT1 SND1 intronic transcript 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBX19 T-box 19
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THOC6 THO complex 6
TLN1 talin 1
TM6SF1 transmembrane 6 superfamily member 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRAIP TRAF interacting protein
TTBK2 tau tubulin kinase 2
UBQLN4 ubiquilin 4
VASH1 vasohibin 1
VEGFB vascular endothelial growth factor B
WDR25 WD repeat domain 25
WDR62 WD repeat domain 62
YEATS4 YEATS domain containing 4
ZFP37 ZFP37 zinc finger protein
ZNF778 zinc finger protein 778