linear Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

159 genes co-occuring with the biological term linear in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2A adenosine A2a receptor
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRB1 adrenoceptor beta 1
AFM afamin
AHI1 Abelson helper integration site 1
ALB albumin
APOA1 apolipoprotein A-I
APOC2 apolipoprotein C-II
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AQP4 aquaporin 4
AR androgen receptor
BCL2 B-cell CLL/lymphoma 2
BMP2 bone morphogenetic protein 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
C1QC complement component 1, q subcomponent, C chain
CALB2 calbindin 2
CALCA calcitonin-related polypeptide alpha
CASC5 cancer susceptibility candidate 5
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CASKIN1 CASK interacting protein 1
CASQ2 calsequestrin 2 (cardiac muscle)
CCL2 chemokine (C-C motif) ligand 2
CDC42 cell division cycle 42
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CETN2 centrin, EF-hand protein, 2
CETP cholesteryl ester transfer protein, plasma
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHGA chromogranin A
CHRM3 cholinergic receptor, muscarinic 3
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COL4A5 collagen, type IV, alpha 5
COMT catechol-O-methyltransferase
COX7B cytochrome c oxidase subunit VIIb
CP ceruloplasmin (ferroxidase)
CRP C-reactive protein, pentraxin-related
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DAAM1 dishevelled associated activator of morphogenesis 1
DEFB103B defensin, beta 103B
DIAPH1 diaphanous-related formin 1
DLG4 discs, large homolog 4 (Drosophila)
DMPK dystrophia myotonica-protein kinase
DNMBP dynamin binding protein
DSG1 desmoglein 1
DSG3 desmoglein 3
EGFR epidermal growth factor receptor
EIF4A2 eukaryotic translation initiation factor 4A2
ESR2 estrogen receptor 2 (ER beta)
FASLG Fas ligand (TNF superfamily, member 6)
FDX1 ferredoxin 1
FDXR ferredoxin reductase
FGF10 fibroblast growth factor 10
FGF2 fibroblast growth factor 2 (basic)
FLII flightless I homolog (Drosophila)
FOXO1 forkhead box O1
FTO fat mass and obesity associated
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GC group-specific component (vitamin D binding protein)
GCH1 GTP cyclohydrolase 1
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HBA1 hemoglobin, alpha 1
HCCS holocytochrome c synthase
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGA2 high mobility group AT-hook 2
HRAS Harvey rat sarcoma viral oncogene homolog
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL6 interleukin 6
INPPL1 inositol polyphosphate phosphatase-like 1
ISL1 ISL LIM homeobox 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KLK3 kallikrein-related peptidase 3
LCAT lecithin-cholesterol acyltransferase
LEP leptin
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MC4R melanocortin 4 receptor
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MGMT O-6-methylguanine-DNA methyltransferase
MIR143 microRNA 143
MIR145 microRNA 145
MIR146A microRNA 146a
MIR155 microRNA 155
MLXIPL MLX interacting protein-like
MOG myelin oligodendrocyte glycoprotein
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC5B mucin 5B, oligomeric mucus/gel-forming
NAMPT nicotinamide phosphoribosyltransferase
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPPB natriuretic peptide B
NPPC natriuretic peptide C
NRG1 neuregulin 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OTULIN OTU deubiquitinase with linear linkage specificity
PILRA paired immunoglobin-like type 2 receptor alpha
PLAU plasminogen activator, urokinase
POC5 POC5 centriolar protein
PON1 paraoxonase 1
PRSS50 protease, serine, 50
PTBP1 polypyrimidine tract binding protein 1
PTH parathyroid hormone
PTHLH parathyroid hormone-like hormone
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RET ret proto-oncogene
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNF31 ring finger protein 31
SCN9A sodium channel, voltage gated, type IX alpha subunit
SETD8 SET domain containing (lysine methyltransferase) 8
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SORT1 sortilin 1
SOST sclerostin
TERF2 telomeric repeat binding factor 2
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TLN1 talin 1
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
UBC ubiquitin C
UBD ubiquitin D
UBE2L3 ubiquitin-conjugating enzyme E2L 3
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VKORC1 vitamin K epoxide reductase complex, subunit 1
WNT4 wingless-type MMTV integration site family, member 4
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa