liothyronine-2984 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the liothyronine-2984 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ADAM22 ADAM metallopeptidase domain 22
ADGRE1 adhesion G protein-coupled receptor E1
AK1 adenylate kinase 1
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANG angiogenin, ribonuclease, RNase A family, 5
ANKRD53 ankyrin repeat domain 53
AOC3 amine oxidase, copper containing 3
AREG amphiregulin
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
BCL2L1 BCL2-like 1
BDNF brain-derived neurotrophic factor
BMP7 bone morphogenetic protein 7
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C8ORF4 chromosome 8 open reading frame 4
C9ORF9 chromosome 9 open reading frame 9
CALD1 caldesmon 1
CALML3 calmodulin-like 3
CCDC28B coiled-coil domain containing 28B
CD160 CD160 molecule
CDRT1 CMT1A duplicated region transcript 1
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CRABP2 cellular retinoic acid binding protein 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXXC4 CXXC finger protein 4
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DKFZP434C153 DKFZP434C153 protein
DLK2 delta-like 2 homolog (Drosophila)
EDDM3B epididymal protein 3B
EGFR epidermal growth factor receptor
ELL2 elongation factor, RNA polymerase II, 2
EXOG endo/exonuclease (5'-3'), endonuclease G-like
FAM135A family with sequence similarity 135, member A
FDPS farnesyl diphosphate synthase
GLRB glycine receptor, beta
HOXA10 homeobox A10
HOXB3 homeobox B3
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IAPP islet amyloid polypeptide
IL22 interleukin 22
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KHK ketohexokinase (fructokinase)
KLK12 kallikrein-related peptidase 12
KLK2 kallikrein-related peptidase 2
KLK5 kallikrein-related peptidase 5
LAMB4 laminin, beta 4
LAMP1 lysosomal-associated membrane protein 1
LDHC lactate dehydrogenase C
LIMD2 LIM domain containing 2
LRP2 low density lipoprotein receptor-related protein 2
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP2K7 mitogen-activated protein kinase kinase 7
MED14 mediator complex subunit 14
MET MET proto-oncogene, receptor tyrosine kinase
MNMIP1 manchette microtubule inner protein 1
MOXD1 monooxygenase, DBH-like 1
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A
MST1 macrophage stimulating 1
NEBL nebulette
NEK11 NIMA-related kinase 11
NKX2-1 NK2 homeobox 1
NMU neuromedin U
NOL10 nucleolar protein 10
NTN1 netrin 1
NXPE4 neurexophilin and PC-esterase domain family, member 4
PAGE4 P antigen family, member 4 (prostate associated)
PLAC4 placenta-specific 4
PRB1 proline-rich protein BstNI subfamily 1
PVR poliovirus receptor
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
RBP4 retinol binding protein 4, plasma
RND1 Rho family GTPase 1
RNF25 ring finger protein 25
RRBP1 ribosome binding protein 1
SEMG2 semenogelin II
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SLC6A16 solute carrier family 6, member 16
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SORBS2 sorbin and SH3 domain containing 2
SORT1 sortilin 1
SPATA2L spermatogenesis associated 2-like
SSTR4 somatostatin receptor 4
STAB1 stabilin 1
STS steroid sulfatase (microsomal), isozyme S
SYN3 synapsin III
TACR1 tachykinin receptor 1
TADA3 transcriptional adaptor 3
TAPT1 transmembrane anterior posterior transformation 1
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TSC2 tuberous sclerosis 2
VCX2 variable charge, X-linked 2
WIZ widely interspaced zinc finger motifs
ZNF137P zinc finger protein 137, pseudogene
ZNF695 zinc finger protein 695

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AIM2 absent in melanoma 2
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ARL15 ADP-ribosylation factor-like 15
ARMCX4 armadillo repeat containing, X-linked 4
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B3GAT3 beta-1,3-glucuronyltransferase 3
BAG4 BCL2-associated athanogene 4
BSPRY B-box and SPRY domain containing
C3ORF18 chromosome 3 open reading frame 18
C6ORF47 chromosome 6 open reading frame 47
CCDC71 coiled-coil domain containing 71
CDK20 cyclin-dependent kinase 20
CDON cell adhesion associated, oncogene regulated
CLASRP CLK4-associating serine/arginine rich protein
CNN2 calponin 2
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CST1 cystatin SN
CTSD cathepsin D
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DOLK dolichol kinase
DSPP dentin sialophosphoprotein
ENO3 enolase 3 (beta, muscle)
EYA3 EYA transcriptional coactivator and phosphatase 3
FBXL7 F-box and leucine-rich repeat protein 7
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GBP2 guanylate binding protein 2, interferon-inducible
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HIST1H1D histone cluster 1, H1d
HIST1H2BI histone cluster 1, H2bi
HOXC10 homeobox C10
IBSP integrin-binding sialoprotein
IFNA14 interferon, alpha 14
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCTD7 potassium channel tetramerization domain containing 7
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KRT12 keratin 12, type I
LOC157562 uncharacterized LOC157562
LRP3 low density lipoprotein receptor-related protein 3
MAGEF1 melanoma antigen family F1
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MBNL3 muscleblind-like splicing regulator 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL1 methyltransferase like 1
MFSD11 major facilitator superfamily domain containing 11
MMP9 matrix metallopeptidase 9
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NBEAL2 neurobeachin-like 2
NCKAP1L NCK-associated protein 1-like
NMUR1 neuromedin U receptor 1
NUBP2 nucleotide binding protein 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PHC1 polyhomeotic homolog 1 (Drosophila)
POMZP3 POM121 and ZP3 fusion
PRR7 proline rich 7 (synaptic)
PYGB phosphorylase, glycogen; brain
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNF31 ring finger protein 31
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SERINC5 serine incorporator 5
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SOX12 SRY (sex determining region Y)-box 12
SPATA1 spermatogenesis associated 1
STBD1 starch binding domain 1
STK16 serine/threonine kinase 16
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBXAS1 thromboxane A synthase 1 (platelet)
TCTA T-cell leukemia translocation altered
TCTN2 tectonic family member 2
TEC tec protein tyrosine kinase
TLR8 toll-like receptor 8
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPYL2 TSPY-like 2
TTLL1 tubulin tyrosine ligase-like family member 1
VASP vasodilator-stimulated phosphoprotein
WASF3 WAS protein family, member 3
WT1-AS WT1 antisense RNA
XYLT2 xylosyltransferase II
ZC3H12A zinc finger CCCH-type containing 12A
ZC3H3 zinc finger CCCH-type containing 3
ZNF415 zinc finger protein 415
ZNF696 zinc finger protein 696
ZNF81 zinc finger protein 81