| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the liothyronine-3324 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM12 | ADAM metallopeptidase domain 12 |
| AGBL2 | ATP/GTP binding protein-like 2 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AMN | amnion associated transmembrane protein |
| ANGPT1 | angiopoietin 1 |
| APOL2 | apolipoprotein L, 2 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CALCR | calcitonin receptor |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
| CDK13 | cyclin-dependent kinase 13 |
| CEP112 | centrosomal protein 112kDa |
| CIB2 | calcium and integrin binding family member 2 |
| CLDN18 | claudin 18 |
| COL11A2 | collagen, type XI, alpha 2 |
| COL1A2 | collagen, type I, alpha 2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTSS | cathepsin S |
| DEAF1 | DEAF1 transcription factor |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| EPHB2 | EPH receptor B2 |
| FETUB | fetuin B |
| FKRP | fukutin related protein |
| FN1 | fibronectin 1 |
| FOXN3 | forkhead box N3 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GSN-AS1 | GSN antisense RNA 1 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HOXD11 | homeobox D11 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL23A | interleukin 23, alpha subunit p19 |
| IRF4 | interferon regulatory factor 4 |
| IRS4 | insulin receptor substrate 4 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM8 | lysine (K)-specific demethylase 8 |
| LAG3 | lymphocyte-activation gene 3 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MIR622 | microRNA 622 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MUC3B | mucin 3B, cell surface associated |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult |
| MYOZ1 | myozenin 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NME5 | NME/NM23 family member 5 |
| NOP16 | NOP16 nucleolar protein |
| NPC1 | Niemann-Pick disease, type C1 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NRG2 | neuregulin 2 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PDE10A | phosphodiesterase 10A |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PLXNC1 | plexin C1 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PRMT2IP | PRMT2 interacting protein |
| RAB6B | RAB6B, member RAS oncogene family |
| RASA3 | RAS p21 protein activator 3 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RND1 | Rho family GTPase 1 |
| SAFB2 | scaffold attachment factor B2 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| STRN | striatin, calmodulin binding protein |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TAGLN3 | transgelin 3 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TCP10L | t-complex 10-like |
| TIGD6 | tigger transposable element derived 6 |
| TK2 | thymidine kinase 2, mitochondrial |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMPRSS4 | transmembrane protease, serine 4 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TUBB7P | tubulin, beta 7, pseudogene |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| UROD | uroporphyrinogen decarboxylase |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| Symbol | Name |
|---|---|
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ALS2CL | ALS2 C-terminal like |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BCL2L2 | BCL2-like 2 |
| BCORL1 | BCL6 corepressor-like 1 |
| BMP4 | bone morphogenetic protein 4 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CCDC121 | coiled-coil domain containing 121 |
| CCNK | cyclin K |
| CCP110 | centriolar coiled coil protein 110kDa |
| CENPO | centromere protein O |
| CEP97 | centrosomal protein 97kDa |
| CHKB | choline kinase beta |
| CORO7 | coronin 7 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) |
| DUSP8 | dual specificity phosphatase 8 |
| DVL1 | dishevelled segment polarity protein 1 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| EXOC6B | exocyst complex component 6B |
| FAM46C | family with sequence similarity 46, member C |
| FAM63A | family with sequence similarity 63, member A |
| FKBP5 | FK506 binding protein 5 |
| FOXI1 | forkhead box I1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GMPR | guanosine monophosphate reductase |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC5 | histone deacetylase 5 |
| HIST1H1E | histone cluster 1, H1e |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HMHA1 | histocompatibility (minor) HA-1 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IRX4 | iroquois homeobox 4 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| JUNB | jun B proto-oncogene |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0754 | KIAA0754 |
| KIAA0894 | KIAA0894 protein |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LMBR1L | limb development membrane protein 1-like |
| LMNB1 | lamin B1 |
| MYO1D | myosin ID |
| NDE1 | nudE neurodevelopment protein 1 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDHA6 | protocadherin alpha 6 |
| PCDHA9 | protocadherin alpha 9 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PSKH1 | protein serine kinase H1 |
| RAB3D | RAB3D, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| ROM1 | retinal outer segment membrane protein 1 |
| RRAGB | Ras-related GTP binding B |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SDC3 | syndecan 3 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SYBU | syntabulin (syntaxin-interacting) |
| TBC1D2 | TBC1 domain family, member 2 |
| TMC5 | transmembrane channel-like 5 |
| TMC7 | transmembrane channel-like 7 |
| TMEM39B | transmembrane protein 39B |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| UBQLN4 | ubiquilin 4 |
| UBXN6 | UBX domain protein 6 |
| UNC119 | unc-119 homolog (C. elegans) |
| UPP1 | uridine phosphorylase 1 |
| USP20 | ubiquitin specific peptidase 20 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VEGFC | vascular endothelial growth factor C |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF35 | zinc finger protein 35 |
| ZNF573 | zinc finger protein 573 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
