lipid metabolic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. (Gene Ontology, GO_0006629)
External Link http://amigo.geneontology.org/amigo/term/GO:0006629
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Genes

260 genes participating in the lipid metabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AASDH aminoadipate-semialdehyde dehydrogenase
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4
ABHD11 abhydrolase domain containing 11
ABHD15 abhydrolase domain containing 15
ACADL acyl-CoA dehydrogenase, long chain
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACBD4 acyl-CoA binding domain containing 4
ACBD5 acyl-CoA binding domain containing 5
ACBD7 acyl-CoA binding domain containing 7
ACD adrenocortical dysplasia homolog (mouse)
ACLY ATP citrate lyase
ACOT1 acyl-CoA thioesterase 1
ACOT11 acyl-CoA thioesterase 11
ACOT2 acyl-CoA thioesterase 2
ACOT4 acyl-CoA thioesterase 4
ACOT6 acyl-CoA thioesterase 6
ACOX1 acyl-CoA oxidase 1, palmitoyl
ACP6 acid phosphatase 6, lysophosphatidic
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACSF2 acyl-CoA synthetase family member 2
ACSF3 acyl-CoA synthetase family member 3
ACSL1 acyl-CoA synthetase long-chain family member 1
ACSL3 acyl-CoA synthetase long-chain family member 3
ACSL4 acyl-CoA synthetase long-chain family member 4
ACSS2 acyl-CoA synthetase short-chain family member 2
AGMO alkylglycerol monooxygenase
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGPS alkylglycerone phosphate synthase
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AKR1C4 aldo-keto reductase family 1, member C4
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALKBH7 alkB, alkylation repair homolog 7 (E. coli)
ALOX12 arachidonate 12-lipoxygenase
ALOX15 arachidonate 15-lipoxygenase
ALOX15B arachidonate 15-lipoxygenase, type B
ANGPTL3 angiopoietin-like 3
ANGPTL8 angiopoietin like 8
AOAH acyloxyacyl hydrolase (neutrophil)
APOA4 apolipoprotein A-IV
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
APOC1 apolipoprotein C-I
APOC4 apolipoprotein C-IV
APOD apolipoprotein D
APOF apolipoprotein F
APOL2 apolipoprotein L, 2
APOL4 apolipoprotein L, 4
APOL5 apolipoprotein L, 5
ATP5F1A ATP synthase F1 subunit alpha
AWAT1 acyl-CoA wax alcohol acyltransferase 1
AWAT2 acyl-CoA wax alcohol acyltransferase 2
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
BAAT bile acid CoA:amino acid N-acyltransferase
BCKDK branched chain ketoacid dehydrogenase kinase
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BTN2A1 butyrophilin, subfamily 2, member A1
C1D C1D nuclear receptor corepressor
CD36 CD36 molecule (thrombospondin receptor)
CEL carboxyl ester lipase
CEPT1 choline/ethanolamine phosphotransferase 1
CES1 carboxylesterase 1
CH25H cholesterol 25-hydroxylase
CHKA choline kinase alpha
CHPT1 choline phosphotransferase 1
CIDEA cell death-inducing DFFA-like effector a
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CLPS colipase, pancreatic
CLU clusterin
CPNE1 copine I
CPNE7 copine VII
CPT1A carnitine palmitoyltransferase 1A (liver)
CPT1B carnitine palmitoyltransferase 1B (muscle)
CPT1C carnitine palmitoyltransferase 1C
CROT carnitine O-octanoyltransferase
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP3A7-CYP3A51P CYP3A7-CYP3A51P readthrough
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6
DGKA diacylglycerol kinase, alpha 80kDa
DGKB diacylglycerol kinase, beta 90kDa
DGKE diacylglycerol kinase, epsilon 64kDa
DGKG diacylglycerol kinase, gamma 90kDa
DGKQ diacylglycerol kinase, theta 110kDa
DGKZ diacylglycerol kinase, zeta
DHCR24 24-dehydrocholesterol reductase
DHRS4 dehydrogenase/reductase (SDR family) member 4
DHRS9 dehydrogenase/reductase (SDR family) member 9
DOK7 docking protein 7
ECHDC3 enoyl CoA hydratase domain containing 3
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6
FA2H fatty acid 2-hydroxylase
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP6 fatty acid binding protein 6, ileal
FADS2 fatty acid desaturase 2
FADS6 fatty acid desaturase 6
FAM135A family with sequence similarity 135, member A
FAM135B family with sequence similarity 135, member B
FASN fatty acid synthase
GAL3ST1 galactose-3-O-sulfotransferase 1
GDE1 glycerophosphodiester phosphodiesterase 1
GGPS1 geranylgeranyl diphosphate synthase 1
GGT1 gamma-glutamyltransferase 1
GGT5 gamma-glutamyltransferase 5
GPAT4 glycerol-3-phosphate acyltransferase 4
GPX4 glutathione peroxidase 4
GPX5 glutathione peroxidase 5
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HSPG2 heparan sulfate proteoglycan 2
KRTAP11-1 keratin associated protein 11-1
LCAT lecithin-cholesterol acyltransferase
LDLR low density lipoprotein receptor
LEP leptin
LGALS13 lectin, galactoside-binding, soluble, 13
LIPE lipase, hormone-sensitive
LIPG lipase, endothelial
LIPH lipase, member H
LIPI lipase, member I
LIPT1 lipoyltransferase 1
LOC107987479 cytochrome P450 2D6
LPA lipoprotein, Lp(a)
LPCAT3 lysophosphatidylcholine acyltransferase 3
LPCAT4 lysophosphatidylcholine acyltransferase 4
LPIN2 lipin 2
LPL lipoprotein lipase
LRP2 low density lipoprotein receptor-related protein 2
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
MBOAT1 membrane bound O-acyltransferase domain containing 1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MBOAT4 membrane bound O-acyltransferase domain containing 4
MBOAT7 membrane bound O-acyltransferase domain containing 7
MECR mitochondrial trans-2-enoyl-CoA reductase
MGLL monoglyceride lipase
MGST2 microsomal glutathione S-transferase 2
MGST3 microsomal glutathione S-transferase 3
MLXIPL MLX interacting protein-like
MSMO1 methylsterol monooxygenase 1
MTLN mitoregulin
MTTP microsomal triglyceride transfer protein
MUSK muscle, skeletal, receptor tyrosine kinase
NAAA N-acylethanolamine acid amidase
NCEH1 neutral cholesterol ester hydrolase 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
OCRL oculocerebrorenal syndrome of Lowe
OLAH oleoyl-ACP hydrolase
OMA1 OMA1 zinc metallopeptidase
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCCA propionyl CoA carboxylase, alpha polypeptide
PCCB propionyl CoA carboxylase, beta polypeptide
PDE3A phosphodiesterase 3A, cGMP-inhibited
PER2 period circadian clock 2
PHYH phytanoyl-CoA 2-hydroxylase
PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1
PITPNA phosphatidylinositol transfer protein, alpha
PITPNB phosphatidylinositol transfer protein, beta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA1A phospholipase A1 member A
PLA2G15 phospholipase A2, group XV
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G2D phospholipase A2, group IID
PLA2G2E phospholipase A2, group IIE
PLA2G3 phospholipase A2, group III
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLA2G5 phospholipase A2, group V
PLAA phospholipase A2-activating protein
PLAAT3 phospholipase A and acyltransferase 3
PLAAT4 phospholipase A and acyltransferase 4
PLB1 phospholipase B1
PLCB2 phospholipase C, beta 2
PLCD1 phospholipase C, delta 1
PLIN1 perilipin 1
PLPP1 phospholipid phosphatase 1
PLPP2 phospholipid phosphatase 2
PLPP3 phospholipid phosphatase 3
PLPP4 phospholipid phosphatase 4
PLPP5 phospholipid phosphatase 5
PLPP6 phospholipid phosphatase 6
PLPPR1 phospholipid phosphatase related 1
PLPPR2 phospholipid phosphatase related 2
PLPPR3 phospholipid phosphatase related 3
PLPPR4 phospholipid phosphatase related 4
PLPPR5 phospholipid phosphatase related 5
PLTP phospholipid transfer protein
PM20D1 peptidase M20 domain containing 1
PNLIP pancreatic lipase
PNPLA8 patatin-like phospholipase domain containing 8
PORCN porcupine homolog (Drosophila)
PPARA peroxisome proliferator-activated receptor alpha
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPT1 palmitoyl-protein thioesterase 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PTGES2 prostaglandin E synthase 2
RBP3 retinol binding protein 3, interstitial
RDH16 retinol dehydrogenase 16 (all-trans)
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RICTOR RPTOR independent companion of MTOR, complex 2
SDR9C7 short chain dehydrogenase/reductase family 9C, member 7
SGPL1 sphingosine-1-phosphate lyase 1
SIRT2 sirtuin 2
SLC16A11 solute carrier family 16, member 11
SLC22A24 solute carrier family 22, member 24
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SOAT2 sterol O-acyltransferase 2
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
STARD3 StAR-related lipid transfer (START) domain containing 3
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
THEM4 thioesterase superfamily member 4
TIPE3 TNF alpha induced protein 8 like 3
TMEM43 transmembrane protein 43
TMEM86B transmembrane protein 86B
TPRA1 transmembrane protein, adipocyte asscociated 1
TSPO translocator protein (18kDa)
TTPA tocopherol (alpha) transfer protein
UBL4A ubiquitin-like 4A
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
ZNF202 zinc finger protein 202
ZNF670 zinc finger protein 670