lipodystrophy Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

196 genes co-occuring with the disease lipodystrophy in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
LMNA lamin A/C 2.76596
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 2.52928
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 2.45589
LEP leptin 2.09618
LPIN1 lipin 1 2.07487
INS insulin 1.90567
ZMPSTE24 zinc metallopeptidase STE24 1.79165
EMD emerin 1.74869
PPARG peroxisome proliferator-activated receptor gamma 1.72319
LMNB2 lamin B2 1.60234
PTRF polymerase I and transcript release factor 1.60189
CD4 CD4 molecule 1.58983
CARTPT CART prepropeptide 1.49569
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 1.40964
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 1.38123
SREBF1 sterol regulatory element binding transcription factor 1 1.32891
CIDEC cell death-inducing DFFA-like effector c 1.3145
HMGA2 high mobility group AT-hook 2 1.30925
GHRH growth hormone releasing hormone 1.17636
LPIN2 lipin 2 1.12445
INSR insulin receptor 1.0816
LPIN3 lipin 3 1.07404
PLIN1 perilipin 1 1.05723
LMNB1 lamin B1 1.04504
CAV1 caveolin 1, caveolae protein, 22kDa 1.00246
RETN resistin 0.997392
CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 0.987693
AP1S3 adaptor-related protein complex 1, sigma 3 subunit 0.985585
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 0.974221
CTDNEP1 CTD nuclear envelope phosphatase 1 0.886389
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.874509
IGF1 insulin-like growth factor 1 (somatomedin C) 0.869187
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6 0.869187
RCE1 Ras converting CAAX endopeptidase 1 0.815924
NRM nurim (nuclear envelope membrane protein) 0.811821
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 0.789672
DLK1 delta-like 1 homolog (Drosophila) 0.782707
LBR lamin B receptor 0.77207
EXOSC4 exosome component 4 0.751271
FITM2 fat storage-inducing transmembrane protein 2 0.737865
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.734217
S100B S100 calcium binding protein B 0.726929
POLG polymerase (DNA directed), gamma 0.724907
FGF21 fibroblast growth factor 21 0.715618
APOB apolipoprotein B 0.714005
LPL lipoprotein lipase 0.711587
BANF1 barrier to autointegration factor 1 0.708767
PPARA peroxisome proliferator-activated receptor alpha 0.70233
APOC3 apolipoprotein C-III 0.700321
LEMD3 LEM domain containing 3 0.688291
ADIG adipogenin 0.67113
LDLR low density lipoprotein receptor 0.669936
SIK3 SIK family kinase 3 0.661197
RBP4 retinol binding protein 4, plasma 0.658026
IL6 interleukin 6 0.651298
ART5 ADP-ribosyltransferase 5 0.643797
SYNE3 spectrin repeat containing, nuclear envelope family member 3 0.636315
FABP4 fatty acid binding protein 4, adipocyte 0.623751
ICMT isoprenylcysteine carboxyl methyltransferase 0.589001
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.583163
FBN1 fibrillin 1 0.577716
CRABP2 cellular retinoic acid binding protein 2 0.569941
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.554791
KLF3 Kruppel-like factor 3 (basic) 0.552075
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 0.545093
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.542767
IGFBP3 insulin-like growth factor binding protein 3 0.522659
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.508041
SRY sex determining region Y 0.503441
TNF tumor necrosis factor 0.501527
IL18 interleukin 18 0.501527
ADIPOQ adiponectin, C1Q and collagen domain containing 0.495029
APOA1 apolipoprotein A-I 0.494266
IRS1 insulin receptor substrate 1 0.491978
C3 complement component 3 0.487407
HRAS Harvey rat sarcoma viral oncogene homolog 0.487027
GHRL ghrelin/obestatin prepropeptide 0.479427
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 0.472982
MIR346 microRNA 346 0.466928
CAV3 caveolin 3 0.460506
PNPLA2 patatin-like phospholipase domain containing 2 0.457109
MIOX myo-inositol oxygenase 0.440914
TYROBP TYRO protein tyrosine kinase binding protein 0.438658
FNTA farnesyltransferase, CAAX box, alpha 0.436402
LMF1 lipase maturation factor 1 0.435275
ISYNA1 inositol-3-phosphate synthase 1 0.431894
PROKR1 prokineticin receptor 1 0.42289
DIO2 deiodinase, iodothyronine, type II 0.42289
CRABP1 cellular retinoic acid binding protein 1 0.413527
NAP1L1 nucleosome assembly protein 1-like 1 0.404184
LCOR ligand dependent nuclear receptor corepressor 0.399707
CD68 CD68 molecule 0.397098
WNT10B wingless-type MMTV integration site family, member 10B 0.383337
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.381481
SCARB2 scavenger receptor class B, member 2 0.380739
PPOX protoporphyrinogen oxidase 0.379997
FASN fatty acid synthase 0.378143
FAT3 FAT atypical cadherin 3 0.37629
ADRB3 adrenoceptor beta 3 0.374809
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.372587
CHURC1 churchill domain containing 1 0.36704
FAT2 FAT atypical cadherin 2 0.36704
CD36 CD36 molecule (thrombospondin receptor) 0.365193
YIPF2 Yip1 domain family, member 2 0.364454
PNPLA8 patatin-like phospholipase domain containing 8 0.358183
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.353027
SUDS3 suppressor of defective silencing 3 homolog (S. cerevisiae) 0.349717
WRN Werner syndrome, RecQ helicase-like 0.349717
PPP1R3A protein phosphatase 1, regulatory subunit 3A 0.348614
IL18BP interleukin 18 binding protein 0.347511
RANBP1 RAN binding protein 1 0.346409
ACAA2 acetyl-CoA acyltransferase 2 0.34384
SUN1 Sad1 and UNC84 domain containing 1 0.343473
OMA1 OMA1 zinc metallopeptidase 0.342739
GPAM glycerol-3-phosphate acyltransferase, mitochondrial 0.342006
EBF1 early B-cell factor 1 0.342006
AEBP1 AE binding protein 1 0.341639
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 0.332852
SH3PXD2B SH3 and PX domains 2B 0.326281
SCARB1 scavenger receptor class B, member 1 0.325552
MYF5 myogenic factor 5 0.323002
MIR186 microRNA 186 0.317909
NAMPT nicotinamide phosphoribosyltransferase 0.316819
G0S2 G0/G1 switch 2 0.309928
MATR3 matrin 3 0.309566
CRP C-reactive protein, pentraxin-related 0.304142
WNT10A wingless-type MMTV integration site family, member 10A 0.299452
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.296571
CFP complement factor properdin 0.296211
MSTN myostatin 0.295132
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.284728
ERCC8 excision repair cross-complementation group 8 0.280439
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 0.268687
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.265494
LEPR leptin receptor 0.263368
RXRG retinoid X receptor, gamma 0.262306
KLB klotho beta 0.260184
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 0.253127
COG2 component of oligomeric golgi complex 2 0.252774
HADH hydroxyacyl-CoA dehydrogenase 0.249608
GHR growth hormone receptor 0.247501
RECQL5 RecQ protein-like 5 0.247501
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 0.246448
PCSK1 proprotein convertase subtilisin/kexin type 1 0.241895
ADD1 adducin 1 (alpha) 0.238403
ACVR2B activin A receptor, type IIB 0.238054
IGFBP1 insulin-like growth factor binding protein 1 0.238054
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.235616
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.23492
ARR3 arrestin 3, retinal (X-arrestin) 0.232489
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase 0.225229
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 0.223853
SHBG sex hormone-binding globulin 0.220424
PLIN3 perilipin 3 0.220424
GK glycerol kinase 0.220424
EP300 E1A binding protein p300 0.217693
GPC3 glypican 3 0.216332
ABHD5 abhydrolase domain containing 5 0.216332
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 0.212945
DGAT2 diacylglycerol O-acyltransferase 2 0.212271
DIO3 deiodinase, iodothyronine, type III 0.205585
MYOG myogenin (myogenic factor 4) 0.204593
SREBF2 sterol regulatory element binding transcription factor 2 0.202946
PITX2 paired-like homeodomain 2 0.190786
MIRLET7D microRNA let-7d 0.187719
PIR pirin (iron-binding nuclear protein) 0.185313
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) 0.185016
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 0.182666
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.179239
LIPE lipase, hormone-sensitive 0.17896
TRIB1 tribbles pseudokinase 1 0.175411
CS citrate synthase 0.174354
ADIPOR2 adiponectin receptor 2 0.170054
GCG glucagon 0.165874
GATA2 GATA binding protein 2 0.164571
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.164359
NUP153 nucleoporin 153kDa 0.163317
APOE apolipoprotein E 0.163317
GSK3A glycogen synthase kinase 3 alpha 0.160387
MIR191 microRNA 191 0.158951
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 0.153311
MC4R melanocortin 4 receptor 0.145342
MKL1 megakaryoblastic leukemia (translocation) 1 0.143226
CTH cystathionine gamma-lyase 0.143125
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 0.142738
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 0.142414
MLXIPL MLX interacting protein-like 0.141879
RXRA retinoid X receptor, alpha 0.141749
CFD complement factor D (adipsin) 0.140061
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.139217
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.139023
CAPN10 calpain 10 0.138988
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.138056
THRB thyroid hormone receptor, beta 0.136827
CAPN3 calpain 3, (p94) 0.136664
FKTN fukutin 0.134666