| Dataset | MPO Gene-Phenotype Associations |
| Category | disease or phenotype associations |
| Type | phenotype |
| Description | accumulation of intracellular autofluorescent material, in the form of brownish fatty pigment, in lysosomes as a normal part of senescence or aging (Mammalian Phenotype Ontology, MP_0008842) |
| External Link | http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008842 |
| Similar Terms | |
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10 gene mutations causing the lipofuscinosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
| Symbol | Name |
|---|---|
| ATP13A2 | ATPase type 13A2 |
| CCL13 | chemokine (C-C motif) ligand 13 |
| CCR2 | chemokine (C-C motif) receptor 2 |
| CERS1 | ceramide synthase 1 |
| GLMP | glycosylated lysosomal membrane protein |
| GRN | granulin |
| LRRK2 | leucine-rich repeat kinase 2 |
| NHLRC1 | NHL repeat containing E3 ubiquitin protein ligase 1 |
| PPT1 | palmitoyl-protein thioesterase 1 |
| SIRT7 | sirtuin 7 |
