lipopolysaccharide receptor complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated and which functions as a lipopolysaccharide (LPS) receptor that primes the innate immune response against bacterial pathogens. (Gene Ontology, GO_0046696)
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32 proteins co-occuring with the lipopolysaccharide receptor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
TLR4 toll-like receptor 4 2.1224
LY96 lymphocyte antigen 96 2.08745
TLR2 toll-like receptor 2 1.16799
IRAK2 interleukin-1 receptor-associated kinase 2 0.98927
MYD88 myeloid differentiation primary response 88 0.927013
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.841941
IRAK1 interleukin-1 receptor-associated kinase 1 0.818534
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.792396
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa 0.651729
TREM1 triggering receptor expressed on myeloid cells 1 0.555559
LBP lipopolysaccharide binding protein 0.523885
SPI1 Spi-1 proto-oncogene 0.45004
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.439333
HDAC7 histone deacetylase 7 0.420428
IRAK4 interleukin-1 receptor-associated kinase 4 0.41612
PCDH8 protocadherin 8 0.413382
TNF tumor necrosis factor 0.392001
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.354042
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.324951
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.31783
CCL2 chemokine (C-C motif) ligand 2 0.297713
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.27998
CISH cytokine inducible SH2-containing protein 0.275936
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 0.234891
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.232029
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) 0.227397
IRF6 interferon regulatory factor 6 0.210894
CCL4 chemokine (C-C motif) ligand 4 0.206082
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.169604
CD33 CD33 molecule 0.161068
IL1RL1 interleukin 1 receptor-like 1 0.160456
CD40 CD40 molecule, TNF receptor superfamily member 5 0.156513