lipoproteins Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes. (Experimental Factor Ontology, EFO_0003836)
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Genes

88 genes associated with the disease lipoproteins in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
AARS2 alanyl-tRNA synthetase 2, mitochondrial
ADD2 adducin 2 (beta)
AGBL1 ATP/GTP binding protein-like 1
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALCAM activated leukocyte cell adhesion molecule
ANKRD60 ankyrin repeat domain 60
APOA1 apolipoprotein A-I
APOC3 apolipoprotein C-III
ARID1B AT rich interactive domain 1B (SWI1-like)
ASXL3 additional sex combs like transcriptional regulator 3
ATXN1 ataxin 1
BOK BCL2-related ovarian killer
C4ORF22 chromosome 4 open reading frame 22
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CEP128 centrosomal protein 128kDa
CETP cholesteryl ester transfer protein, plasma
CNTN5 contactin 5
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CSMD1 CUB and Sushi multiple domains 1
CSMD2 CUB and Sushi multiple domains 2
CTNND2 catenin (cadherin-associated protein), delta 2
CXXC5 CXXC finger protein 5
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCHS2 dachsous cadherin-related 2
ENDOD1 endonuclease domain containing 1
EPHA8 EPH receptor A8
FABP1 fatty acid binding protein 1, liver
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FHIT fragile histidine triad
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
GATAD2B GATA zinc finger domain containing 2B
GOLGA5 golgin A5
GPM6A glycoprotein M6A
GRHL1 grainyhead-like 1 (Drosophila)
GRIK2 glutamate receptor, ionotropic, kainate 2
IGF2R insulin-like growth factor 2 receptor
IL1RAP interleukin 1 receptor accessory protein
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
ISM1 isthmin 1, angiogenesis inhibitor
KCTD16 potassium channel tetramerization domain containing 16
KDM4C lysine (K)-specific demethylase 4C
LDLR low density lipoprotein receptor
LIPC lipase, hepatic
LPA lipoprotein, Lp(a)
LPAL2 lipoprotein, Lp(a)-like 2, pseudogene
LPL lipoprotein lipase
MACROD2 MACRO domain containing 2
MAP3K4 mitogen-activated protein kinase kinase kinase 4
MCF2 MCF.2 cell line derived transforming sequence
MTTP microsomal triglyceride transfer protein
NAV2 neuron navigator 2
NFIB nuclear factor I/B
NME8 NME/NM23 family member 8
NOVA2 neuro-oncological ventral antigen 2
NRXN1 neurexin 1
NTM neurotrimin
PID1 phosphotyrosine interaction domain containing 1
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLEK pleckstrin
PLG plasminogen
PNLIP pancreatic lipase
PTK2B protein tyrosine kinase 2 beta
PTPRD protein tyrosine phosphatase, receptor type, D
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RNF43 ring finger protein 43
SDC2 syndecan 2
SEPT9 septin 9
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC44A3 solute carrier family 44, member 3
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
SNX29 sorting nexin 29
SORCS1 sortilin-related VPS10 domain containing receptor 1
SYNE3 spectrin repeat containing, nuclear envelope family member 3
THSD4 thrombospondin, type I, domain containing 4
TMEM92 transmembrane protein 92
TRIM42 tripartite motif containing 42
WDFY4 WDFY family member 4
YIPF5 Yip1 domain family, member 5
ZFC3H1 zinc finger, C3H1-type containing
ZNF385D zinc finger protein 385D
ZNF599 zinc finger protein 599