lipoxygenase pathway Gene Set

Dataset	GO Biological Process Annotations 2025
Category	structural or functional annotations
Type	biological process
Description	The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase. (Gene Ontology, GO_0019372)
External Link	http://amigo.geneontology.org/amigo/term/GO:0019372
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Genes

10 genes participating in the lipoxygenase pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol	Name
ALOX12	arachidonate 12-lipoxygenase
ALOX12B	arachidonate 12-lipoxygenase, 12R type
ALOX15	arachidonate 15-lipoxygenase
ALOX15B	arachidonate 15-lipoxygenase, type B
ALOX5	arachidonate 5-lipoxygenase
ALOXE3	arachidonate lipoxygenase 3
GPX1	glutathione peroxidase 1
GPX4	glutathione peroxidase 4
HPGD	hydroxyprostaglandin dehydrogenase 15-(NAD)
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)