| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the lisinopril-2371 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM12 | ADAM metallopeptidase domain 12 |
| ALOX12 | arachidonate 12-lipoxygenase |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| AMN | amnion associated transmembrane protein |
| ANGPTL2 | angiopoietin-like 2 |
| ATRNL1 | attractin-like 1 |
| ATXN2L | ataxin 2-like |
| AURKA | aurora kinase A |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| C14ORF105 | chromosome 14 open reading frame 105 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD5 | CD5 molecule |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CFAP69 | cilia and flagella associated protein 69 |
| CIB2 | calcium and integrin binding family member 2 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNTLN | centlein, centrosomal protein |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| E2F1 | E2F transcription factor 1 |
| EFNA3 | ephrin-A3 |
| EPHB4 | EPH receptor B4 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 |
| ESR1 | estrogen receptor 1 |
| FAM127B | family with sequence similarity 127, member B |
| FBXO22 | F-box protein 22 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FOXG1 | forkhead box G1 |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| GPM6B | glycoprotein M6B |
| GPR153 | G protein-coupled receptor 153 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRM7 | glutamate receptor, metabotropic 7 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HOXA11 | homeobox A11 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IDS | iduronate 2-sulfatase |
| IFI6 | interferon, alpha-inducible protein 6 |
| ING1 | inhibitor of growth family, member 1 |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLF12 | Kruppel-like factor 12 |
| KLK7 | kallikrein-related peptidase 7 |
| KYNU | kynureninase |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MED14 | mediator complex subunit 14 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MUC8 | mucin 8 |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NEBL | nebulette |
| NEK9 | NIMA-related kinase 9 |
| NUDT7 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
| NXPH3 | neurexophilin 3 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PDGFD | platelet derived growth factor D |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PDZK1 | PDZ domain containing 1 |
| PLK4 | polo-like kinase 4 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RBM34 | RNA binding motif protein 34 |
| RECQL5 | RecQ protein-like 5 |
| RGS3 | regulator of G-protein signaling 3 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RUFY3 | RUN and FYVE domain containing 3 |
| RUNX1 | runt-related transcription factor 1 |
| SAA3P | serum amyloid A3 pseudogene |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SHB | Src homology 2 domain containing adaptor protein B |
| SHOX2 | short stature homeobox 2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPHK2 | sphingosine kinase 2 |
| ST7L | suppression of tumorigenicity 7 like |
| STAB1 | stabilin 1 |
| TEX40 | testis expressed 40 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| TUBA3C | tubulin, alpha 3c |
| ULK2 | unc-51 like autophagy activating kinase 2 |
| ZNF34 | zinc finger protein 34 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| AEN | apoptosis enhancing nuclease |
| AKTIP | AKT interacting protein |
| ALPK1 | alpha-kinase 1 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APH1B | APH1B gamma secretase subunit |
| ARSB | arylsulfatase B |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BCORL1 | BCL6 corepressor-like 1 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CA11 | carbonic anhydrase XI |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CAPN5 | calpain 5 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC176 | coiled-coil domain containing 176 |
| CD82 | CD82 molecule |
| CDA | cytidine deaminase |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CEL | carboxyl ester lipase |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CSF1R | colony stimulating factor 1 receptor |
| DENND1C | DENN/MADD domain containing 1C |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| FAM102A | family with sequence similarity 102, member A |
| FAM163A | family with sequence similarity 163, member A |
| FAM184A | family with sequence similarity 184, member A |
| FBRS | fibrosin |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FGGY | FGGY carbohydrate kinase domain containing |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPR27 | G protein-coupled receptor 27 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HCFC2 | host cell factor C2 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HIST1H1E | histone cluster 1, H1e |
| HOPX | HOP homeobox |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IER3 | immediate early response 3 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| IRF7 | interferon regulatory factor 7 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAGEF1 | melanoma antigen family F1 |
| MREG | melanoregulin |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MXD3 | MAX dimerization protein 3 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCS1 | neuronal calcium sensor 1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCYOX1 | prenylcysteine oxidase 1 |
| PDZD7 | PDZ domain containing 7 |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma |
| PKN1 | protein kinase N1 |
| PLS1 | plastin 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRR4 | proline rich 4 (lacrimal) |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB33B | RAB33B, member RAS oncogene family |
| RFXAP | regulatory factor X-associated protein |
| RNF122 | ring finger protein 122 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SHPK | sedoheptulokinase |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC38A6 | solute carrier family 38, member 6 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| STEAP3 | STEAP family member 3, metalloreductase |
| STXBP1 | syntaxin binding protein 1 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| TGM5 | transglutaminase 5 |
| TMEM110 | transmembrane protein 110 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM160 | transmembrane protein 160 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 |
| UBXN6 | UBX domain protein 6 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF747 | zinc finger protein 747 |
