| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the lisinopril-5504 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ANGPTL2 | angiopoietin-like 2 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| ARSD | arylsulfatase D |
| CABIN1 | calcineurin binding protein 1 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CCDC64 | coiled-coil domain containing 64 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CEP164 | centrosomal protein 164kDa |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLGN | calmegin |
| CORO2B | coronin, actin binding protein, 2B |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CREB5 | cAMP responsive element binding protein 5 |
| CSF1R | colony stimulating factor 1 receptor |
| CSH1 | chorionic somatomammotropin hormone 1 (placental lactogen) |
| CST6 | cystatin E/M |
| DCLK1 | doublecortin-like kinase 1 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DOCK3 | dedicator of cytokinesis 3 |
| DSC2 | desmocollin 2 |
| DST | dystonin |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EPHA1 | EPH receptor A1 |
| EVC | Ellis van Creveld protein |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FHL1 | four and a half LIM domains 1 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| FZD9 | frizzled class receptor 9 |
| GAS7 | growth arrest-specific 7 |
| GNMT | glycine N-methyltransferase |
| GPR143 | G protein-coupled receptor 143 |
| GRB10 | growth factor receptor-bound protein 10 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HYI | hydroxypyruvate isomerase (putative) |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IRS2 | insulin receptor substrate 2 |
| ISL1 | ISL LIM homeobox 1 |
| IZUMO4 | IZUMO family member 4 |
| KLF15 | Kruppel-like factor 15 |
| KLHL35 | kelch-like family member 35 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LEFTY1 | left-right determination factor 1 |
| LOC392555 | melanoma antigen family C2 pseudogene |
| LPL | lipoprotein lipase |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MLH3 | mutL homolog 3 |
| MMP13 | matrix metallopeptidase 13 |
| MTRF1L | mitochondrial translational release factor 1-like |
| NF2 | neurofibromin 2 (merlin) |
| NPHS1 | nephrosis 1, congenital, Finnish type (nephrin) |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PAX3 | paired box 3 |
| PDE12 | phosphodiesterase 12 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited |
| PER2 | period circadian clock 2 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PIPOX | pipecolic acid oxidase |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| SBF1 | SET binding factor 1 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SEMG1 | semenogelin I |
| SERHL2 | serine hydrolase-like 2 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SNX1 | sorting nexin 1 |
| SPACA1 | sperm acrosome associated 1 |
| SPAG16 | sperm associated antigen 16 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMEM63A | transmembrane protein 63A |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TRIP11 | thyroid hormone receptor interactor 11 |
| TSHB | thyroid stimulating hormone, beta |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| UPK2 | uroplakin 2 |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) |
| VARS | valyl-tRNA synthetase |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| ZNF747 | zinc finger protein 747 |
| ZNF749 | zinc finger protein 749 |
| ZNF862 | zinc finger protein 862 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| ALPK1 | alpha-kinase 1 |
| ANKRD36B | ankyrin repeat domain 36B |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARMC7 | armadillo repeat containing 7 |
| BAK1 | BCL2-antagonist/killer 1 |
| BBC3 | BCL2 binding component 3 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CASD1 | CAS1 domain containing 1 |
| CBX4 | chromobox homolog 4 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHPF | chondroitin polymerizing factor |
| CXADR | coxsackie virus and adenovirus receptor |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
| EFNA3 | ephrin-A3 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM131A | family with sequence similarity 131, member A |
| FBXO22 | F-box protein 22 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FLCN | folliculin |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HHLA3 | HERV-H LTR-associating 3 |
| HIRA | histone cell cycle regulator |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H4D | histone cluster 1, H4d |
| HMOX1 | heme oxygenase 1 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA0894 | KIAA0894 protein |
| KIZ | kizuna centrosomal protein |
| KLHL26 | kelch-like family member 26 |
| LAMA3 | laminin, alpha 3 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MED22 | mediator complex subunit 22 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| NABP2 | nucleic acid binding protein 2 |
| NCAPH | non-SMC condensin I complex, subunit H |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NLRX1 | NLR family member X1 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| NUPL2 | nucleoporin like 2 |
| ONECUT2 | one cut homeobox 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OTUD3 | OTU deubiquitinase 3 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PCBP4 | poly(rC) binding protein 4 |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PGP | phosphoglycolate phosphatase |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PKN1 | protein kinase N1 |
| PRSS8 | protease, serine, 8 |
| PSKH1 | protein serine kinase H1 |
| RANGRF | RAN guanine nucleotide release factor |
| RNF122 | ring finger protein 122 |
| SCHIP1 | schwannomin interacting protein 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMIM14 | small integral membrane protein 14 |
| SP140L | SP140 nuclear body protein-like |
| SUSD6 | sushi domain containing 6 |
| TCTA | T-cell leukemia translocation altered |
| TESK2 | testis-specific kinase 2 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TXLNA | taxilin alpha |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBQLN4 | ubiquilin 4 |
| UROS | uroporphyrinogen III synthase |
| USP18 | ubiquitin specific peptidase 18 |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| WDR19 | WD repeat domain 19 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZNF141 | zinc finger protein 141 |
| ZNF219 | zinc finger protein 219 |
| ZNF248 | zinc finger protein 248 |
| ZNF350 | zinc finger protein 350 |
| ZNF365 | zinc finger protein 365 |
| ZNF480 | zinc finger protein 480 |
| ZNF586 | zinc finger protein 586 |
| ZNF652 | zinc finger protein 652 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
