lisuride-1545 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the lisuride-1545 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADAP2 ArfGAP with dual PH domains 2
ADCY7 adenylate cyclase 7
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AKAP7 A kinase (PRKA) anchor protein 7
AMPD3 adenosine monophosphate deaminase 3
ANAPC13 anaphase promoting complex subunit 13
APOC1 apolipoprotein C-I
BMP1 bone morphogenetic protein 1
BRCA2 breast cancer 2, early onset
C19ORF66 chromosome 19 open reading frame 66
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCDC40 coiled-coil domain containing 40
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CD1E CD1e molecule
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COL5A2 collagen, type V, alpha 2
CRIP1 cysteine-rich protein 1 (intestinal)
CUL4A cullin 4A
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DPF1 D4, zinc and double PHD fingers family 1
DPYSL4 dihydropyrimidinase-like 4
DST dystonin
EFNB3 ephrin-B3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ERCC2 excision repair cross-complementation group 2
FASTKD2 FAST kinase domains 2
FCMR Fc fragment of IgM receptor
FLOT1 flotillin 1
FOSL2 FOS-like antigen 2
FRY furry homolog (Drosophila)
GGT1 gamma-glutamyltransferase 1
GM2A GM2 ganglioside activator
GSAP gamma-secretase activating protein
HDAC7 histone deacetylase 7
HFE hemochromatosis
HIST1H2AL histone cluster 1, H2al
HIST1H4E histone cluster 1, H4e
IDI2-AS1 IDI2 antisense RNA 1
IFIH1 interferon induced with helicase C domain 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGHMBP2 immunoglobulin mu binding protein 2
IL5RA interleukin 5 receptor, alpha
ISG20 interferon stimulated exonuclease gene 20kDa
KIDINS220 kinase D-interacting substrate, 220kDa
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF6 Kruppel-like factor 6
KRT8 keratin 8, type II
MARK4 MAP/microtubule affinity-regulating kinase 4
MBTD1 mbt domain containing 1
MTA1 metastasis associated 1
MVD mevalonate (diphospho) decarboxylase
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit
NDRG2 NDRG family member 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NMT2 N-myristoyltransferase 2
NOX1 NADPH oxidase 1
NRSN2 neurensin 2
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PARVA parvin, alpha
PCDH12 protocadherin 12
PCDHB13 protocadherin beta 13
PDE4DIP phosphodiesterase 4D interacting protein
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PSG9 pregnancy specific beta-1-glycoprotein 9
PTGES prostaglandin E synthase
PVR poliovirus receptor
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIMS2 regulating synaptic membrane exocytosis 2
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
SCN4A sodium channel, voltage gated, type IV alpha subunit
SFXN3 sideroflexin 3
SH3BP2 SH3-domain binding protein 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SOS2 son of sevenless homolog 2 (Drosophila)
SPARCL1 SPARC-like 1 (hevin)
SRSF7 serine/arginine-rich splicing factor 7
STAC SH3 and cysteine rich domain
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYBU syntabulin (syntaxin-interacting)
SYN2 synapsin II
SYNJ2 synaptojanin 2
TBC1D19 TBC1 domain family, member 19
TEX261 testis expressed 261
TMEM120B transmembrane protein 120B
TMEM209 transmembrane protein 209
TMEM45A transmembrane protein 45A
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TUBA3C tubulin, alpha 3c
USP34 ubiquitin specific peptidase 34
WDHD1 WD repeat and HMG-box DNA binding protein 1
WIPF1 WAS/WASL interacting protein family, member 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF557 zinc finger protein 557
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ALPK1 alpha-kinase 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APLP1 amyloid beta (A4) precursor-like protein 1
ARC activity-regulated cytoskeleton-associated protein
ART1 ADP-ribosyltransferase 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C1ORF105 chromosome 1 open reading frame 105
C1ORF159 chromosome 1 open reading frame 159
C22ORF29 chromosome 22 open reading frame 29
CA5BP1 carbonic anhydrase VB pseudogene 1
CALML5 calmodulin-like 5
CAMTA2 calmodulin binding transcription activator 2
CD1A CD1a molecule
CGA glycoprotein hormones, alpha polypeptide
CHKB choline kinase beta
CNR2 cannabinoid receptor 2 (macrophage)
CRYBB2P1 crystallin, beta B2 pseudogene 1
CRYBG3 beta-gamma crystallin domain containing 3
DEAF1 DEAF1 transcription factor
EDAR ectodysplasin A receptor
EPHA2 EPH receptor A2
ETNK2 ethanolamine kinase 2
FBXO4 F-box protein 4
FER fer (fps/fes related) tyrosine kinase
FGD1 FYVE, RhoGEF and PH domain containing 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLI3 GLI family zinc finger 3
GNL1 guanine nucleotide binding protein-like 1
GRB7 growth factor receptor-bound protein 7
GRTP1 growth hormone regulated TBC protein 1
HCFC2 host cell factor C2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H4J histone cluster 1, H4j
HPN hepsin
IFI35 interferon-induced protein 35
IFNA14 interferon, alpha 14
IFT54 intraflagellar transport 54
IL2RB interleukin 2 receptor, beta
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF7 interferon regulatory factor 7
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KDM5C lysine (K)-specific demethylase 5C
KREMEN2 kringle containing transmembrane protein 2
LHX1 LIM homeobox 1
LOC257152 uncharacterized LOC257152
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LTBP2 latent transforming growth factor beta binding protein 2
MAGEF1 melanoma antigen family F1
MAST3 microtubule associated serine/threonine kinase 3
MMP2 matrix metallopeptidase 2
MSI1 musashi RNA-binding protein 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NPTX1 neuronal pentraxin I
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OSGIN1 oxidative stress induced growth inhibitor 1
PCDHGB5 protocadherin gamma subfamily B, 5
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLAC1 placenta-specific 1
PLTP phospholipid transfer protein
PMM1 phosphomannomutase 1
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PROCR protein C receptor, endothelial
PRPH peripherin
RAB30 RAB30, member RAS oncogene family
RIN2 Ras and Rab interactor 2
RPL13P5 ribosomal protein L13 pseudogene 5
RUSC2 RUN and SH3 domain containing 2
RYR1 ryanodine receptor 1 (skeletal)
S100A4 S100 calcium binding protein A4
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SPIDR scaffolding protein involved in DNA repair
SPINK4 serine peptidase inhibitor, Kazal type 4
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SULT4A1 sulfotransferase family 4A, member 1
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAZ tafazzin
TFF2 trefoil factor 2
THBS3 thrombospondin 3
THNSL2 threonine synthase-like 2 (S. cerevisiae)
THRAP3 thyroid hormone receptor associated protein 3
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNRC6B trinucleotide repeat containing 6B
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TWF2 twinfilin actin binding protein 2
ZBTB22 zinc finger and BTB domain containing 22
ZNF134 zinc finger protein 134
ZNF329 zinc finger protein 329
ZNF34 zinc finger protein 34
ZNF484 zinc finger protein 484
ZNF696 zinc finger protein 696
ZNF76 zinc finger protein 76