lisuride-1962 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the lisuride-1962 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ANGEL1 angel homolog 1 (Drosophila)
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATXN7L3B ataxin 7-like 3B
BAX BCL2-associated X protein
BCL7B B-cell CLL/lymphoma 7B
BLVRA biliverdin reductase A
CACTIN cactin, spliceosome C complex subunit
CAPNS1 calpain, small subunit 1
CCDC85C coiled-coil domain containing 85C
CCRL2 chemokine (C-C motif) receptor-like 2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHKA choline kinase alpha
CIAO1 cytosolic iron-sulfur assembly component 1
CLCC1 chloride channel CLIC-like 1
CLU clusterin
COPS7B COP9 signalosome subunit 7B
CPT2 carnitine palmitoyltransferase 2
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
DAXX death-domain associated protein
DHPS deoxyhypusine synthase
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DOCK10 dedicator of cytokinesis 10
DTNA dystrobrevin, alpha
DUSP6 dual specificity phosphatase 6
ESRRA estrogen-related receptor alpha
FBXO31 F-box protein 31
FGF1 fibroblast growth factor 1 (acidic)
FKBP8 FK506 binding protein 8, 38kDa
FOXO1 forkhead box O1
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GMCL1 germ cell-less, spermatogenesis associated 1
GRK6 G protein-coupled receptor kinase 6
H2AFY2 H2A histone family, member Y2
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
INPP5F inositol polyphosphate-5-phosphatase F
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIAA0141 KIAA0141
KRIT1 KRIT1, ankyrin repeat containing
LDB1 LIM domain binding 1
MAP4 microtubule-associated protein 4
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MNS1 meiosis-specific nuclear structural 1
NAAA N-acylethanolamine acid amidase
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NCOA3 nuclear receptor coactivator 3
NOTCH2 notch 2
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NXT2 nuclear transport factor 2-like export factor 2
OTUD4 OTU deubiquitinase 4
PAQR3 progestin and adipoQ receptor family member III
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PHKG2 phosphorylase kinase, gamma 2 (testis)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLAA phospholipase A2-activating protein
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPCS phosphopantothenoylcysteine synthetase
PREP prolyl endopeptidase
PRPF39 pre-mRNA processing factor 39
PYGB phosphorylase, glycogen; brain
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RARG retinoic acid receptor, gamma
RHOC ras homolog family member C
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RNFT2 ring finger protein, transmembrane 2
RRBP1 ribosome binding protein 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC62 SEC62 homolog (S. cerevisiae)
SEZ6L seizure related 6 homolog (mouse)-like
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC25A44 solute carrier family 25, member 44
SMG5 SMG5 nonsense mediated mRNA decay factor
SNX27 sorting nexin family member 27
SPATA5L1 spermatogenesis associated 5-like 1
SRBD1 S1 RNA binding domain 1
STK10 serine/threonine kinase 10
TCEA2 transcription elongation factor A (SII), 2
TMED2 transmembrane emp24 domain trafficking protein 2
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TPST2 tyrosylprotein sulfotransferase 2
TRIM58 tripartite motif containing 58
TSHB thyroid stimulating hormone, beta
TSKU tsukushi, small leucine rich proteoglycan
TSPYL2 TSPY-like 2
URM1 ubiquitin related modifier 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WASL Wiskott-Aldrich syndrome-like
WDR45 WD repeat domain 45
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZBTB35 zinc finger and BTB domain containing 35
ZMAT5 zinc finger, matrin-type 5
ZNF200 zinc finger protein 200
ZNF609 zinc finger protein 609
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAT1 adenosine deaminase, tRNA-specific 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ANKRD11 ankyrin repeat domain 11
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
ASB6 ankyrin repeat and SOCS box containing 6
ATP11B ATPase, class VI, type 11B
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
C11ORF49 chromosome 11 open reading frame 49
C6ORF47 chromosome 6 open reading frame 47
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDCA4 cell division cycle associated 4
CEP70 centrosomal protein 70kDa
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CNTD2 cyclin N-terminal domain containing 2
CPA2 carboxypeptidase A2 (pancreatic)
CRYL1 crystallin, lambda 1
DNM1 dynamin 1
DPH2 DPH2 homolog (S. cerevisiae)
DRD5 dopamine receptor D5
FAM134C family with sequence similarity 134, member C
FAM173A family with sequence similarity 173, member A
FAM188A family with sequence similarity 188, member A
FAM192A family with sequence similarity 192, member A
FAM193B family with sequence similarity 193, member B
FAM53C family with sequence similarity 53, member C
FXN frataxin
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLB1L2 galactosidase, beta 1-like 2
GRM6 glutamate receptor, metabotropic 6
IER3IP1 immediate early response 3 interacting protein 1
IL24 interleukin 24
JRKL JRK-like
KCTD20 potassium channel tetramerization domain containing 20
KIAA1549L KIAA1549-like
KIF20A kinesin family member 20A
KIF3A kinesin family member 3A
KLC2 kinesin light chain 2
KLHL12 kelch-like family member 12
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KPTN kaptin (actin binding protein)
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LLGL2 lethal giant larvae homolog 2 (Drosophila)
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPK3 mitogen-activated protein kinase 3
MMP9 matrix metallopeptidase 9
MRPL12 mitochondrial ribosomal protein L12
MSL1 male-specific lethal 1 homolog (Drosophila)
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NR1D2 nuclear receptor subfamily 1, group D, member 2
NRSN2 neurensin 2
OCEL1 occludin/ELL domain containing 1
OVGP1 oviductal glycoprotein 1, 120kDa
PADI1 peptidyl arginine deiminase, type I
PARG poly (ADP-ribose) glycohydrolase
PCF11 PCF11 cleavage and polyadenylation factor subunit
PMS2P5 postmeiotic segregation increased 2 pseudogene 5
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PQLC1 PQ loop repeat containing 1
PRMT3 protein arginine methyltransferase 3
PTBP2 polypyrimidine tract binding protein 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RPL23AP32 ribosomal protein L23a pseudogene 32
RPP25 ribonuclease P/MRP 25kDa subunit
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCN10A sodium channel, voltage gated, type X alpha subunit
SDCCAG3 serologically defined colon cancer antigen 3
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SFXN1 sideroflexin 1
SH2D2A SH2 domain containing 2A
SH3GL1 SH3-domain GRB2-like 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SP140L SP140 nuclear body protein-like
SYNE2 spectrin repeat containing, nuclear envelope 2
TAOK1 TAO kinase 1
TCTN2 tectonic family member 2
THAP4 THAP domain containing 4
TMEM242 transmembrane protein 242
TMEM74B transmembrane protein 74B
TOLLIP toll interacting protein
TRIM45 tripartite motif containing 45
TRPS1 trichorhinophalangeal syndrome I
TSEN2 TSEN2 tRNA splicing endonuclease subunit
URGCP upregulator of cell proliferation
VASP vasodilator-stimulated phosphoprotein
WWP2 WW domain containing E3 ubiquitin protein ligase 2
YIPF1 Yip1 domain family, member 1
ZBTB24 zinc finger and BTB domain containing 24
ZNF562 zinc finger protein 562
ZNF623 zinc finger protein 623
ZNF804A zinc finger protein 804A